4EOU

Crystal structure of E. coli dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site

Replaces:  3UBS

Summary for 4EOU

• Entry DOI: 10.2210/pdb4eou/pdb
• Related: 1DHP 1YXC 3DU0
• Descriptor: Dihydrodipicolinate synthase, POTASSIUM ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: alpha/beta barrel, tim barrel, amino-acid biosynthesis, schiff base, lyase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P0A6L2
• Total number of polymer chains: 2
• Total formula weight: 63292.70

Authors

Boughton, B.A.,Dobson, R.C.J.,Hutton, C.A. (deposition date: 2012-04-15, release date: 2012-04-25, Last modification date: 2023-12-06)

• Primary citation: Boughton, B.A.,Dobson, R.C.,Hutton, C.A.; The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product.; Proteins, 80:2117-2122, 2012; PubMed: 22552955; DOI: 10.1002/prot.24106

Experimental method

X-RAY DIFFRACTION (2.3 Å)