7CY5
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![BU of 7cy5 by Molmil](/molmil-images/mine/7cy5) | Crystal Structure of CMD1 in complex with vitamin C | Descriptor: | ASCORBIC ACID, CITRIC ACID, FE (III) ION, ... | Authors: | Li, W, Zhang, T, Sun, M, Ding, J. | Deposit date: | 2020-09-03 | Release date: | 2020-12-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7CY4
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![BU of 7cy4 by Molmil](/molmil-images/mine/7cy4) | Crystal Structure of CMD1 in apo form | Descriptor: | CITRIC ACID, FE (III) ION, Maltodextrin-binding protein,5-methylcytosine-modifying enzyme 1 | Authors: | Li, W, Zhang, T, Sun, M, Ding, J. | Deposit date: | 2020-09-03 | Release date: | 2020-12-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1. Nat Commun, 12, 2021
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7VUX
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![BU of 7vux by Molmil](/molmil-images/mine/7vux) | Complex structure of PD1 and 609A-Fab | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | Deposit date: | 2021-11-04 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties. Mabs, 14, 2022
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7WR1
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![BU of 7wr1 by Molmil](/molmil-images/mine/7wr1) | P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain | Descriptor: | Caspase-4, OspC3 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR4
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![BU of 7wr4 by Molmil](/molmil-images/mine/7wr4) | Crystal structure of OspC3-calmodulin-caspase-4 complex | Descriptor: | Calmodulin-1, Caspase-4, OspC3 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR0
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![BU of 7wr0 by Molmil](/molmil-images/mine/7wr0) | P32 of caspase-4 C258A mutant | Descriptor: | Caspase-4 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR6
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![BU of 7wr6 by Molmil](/molmil-images/mine/7wr6) | Crystal structure of ADP-riboxanated caspase-4 in complex with Af1521 | Descriptor: | ADP-ribose glycohydrolase AF_1521, Caspase-4, [[(3~{a}~{S},5~{R},6~{R},6~{a}~{R})-2-azanylidene-3-[(4~{R})-4-azanyl-5-oxidanylidene-pentyl]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxazol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR2
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![BU of 7wr2 by Molmil](/molmil-images/mine/7wr2) | |
7WR5
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![BU of 7wr5 by Molmil](/molmil-images/mine/7wr5) | Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+ | Descriptor: | Calmodulin-1, Caspase-4, OspC3, ... | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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2MYJ
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![BU of 2myj by Molmil](/molmil-images/mine/2myj) | |
5Y38
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![BU of 5y38 by Molmil](/molmil-images/mine/5y38) | Crystal structure of C7orf59-HBXIP complex | Descriptor: | Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION | Authors: | Zhang, T, Ding, J. | Deposit date: | 2017-07-28 | Release date: | 2017-12-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
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4M6W
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![BU of 4m6w by Molmil](/molmil-images/mine/4m6w) | Crystal structure of the C-terminal segment of FANCM in complex with FAAP24 | Descriptor: | Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION | Authors: | Yang, H, Zhang, T, Tong, L, Ding, J. | Deposit date: | 2013-08-11 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Res., 41, 2013
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1R0A
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![BU of 1r0a by Molmil](/molmil-images/mine/1r0a) | Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms | Descriptor: | 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*GP*GP*T)-3', 5'-D(*C*CP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*AP*GP*CP*GP*CP*CP*GP*(2DA))-3', GLYCEROL, ... | Authors: | Tuske, S, Ding, J, Arnold, E. | Deposit date: | 2003-09-19 | Release date: | 2004-08-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA. J.Virol., 78, 2004
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7F00
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![BU of 7f00 by Molmil](/molmil-images/mine/7f00) | Crystal structure of SPD_0310 | Descriptor: | SULFATE ION, UPF0371 protein SPRM200_0309 | Authors: | Cao, K, Zhang, T, Li, N, Yang, X, Ding, J, He, Q, Sun, X. | Deposit date: | 2021-06-03 | Release date: | 2022-04-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Identification and Tetramer Structure of Hemin-Binding Protein SPD_0310 Linked to Iron Homeostasis and Virulence of Streptococcus pneumoniae. Msystems, 7, 2022
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3SR9
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![BU of 3sr9 by Molmil](/molmil-images/mine/3sr9) | Crystal structure of mouse PTPsigma | Descriptor: | Receptor-type tyrosine-protein phosphatase S | Authors: | Wang, J, Hou, L, Li, J, Ding, J. | Deposit date: | 2011-07-07 | Release date: | 2012-05-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the homology and differences between mouse protein tyrosine phosphatase-sigma and human protein tyrosine phosphatase-sigma Acta Biochim.Biophys.Sin., 43, 2011
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