5B7J
 
 | | Structure model of Sap1-DNA complex | | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1 | | Authors: | Jin, C, Hu, Y, Ding, J, Zhang, Y. | | Deposit date: | 2016-06-07 | | Release date: | 2017-02-22 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe
J. Biol. Chem., 292, 2017
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1L3K
 | | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | | Descriptor: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | | Authors: | Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. | | Deposit date: | 2002-02-27 | | Release date: | 2002-04-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
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3OPT
 | | Crystal structure of the Rph1 catalytic core with a-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, DNA damage-responsive transcriptional repressor RPH1, NICKEL (II) ION | | Authors: | Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J. | | Deposit date: | 2010-09-02 | | Release date: | 2010-12-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism
Biochem.J., 433, 2011
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3OPW
 | | Crystal Structure of the Rph1 catalytic core | | Descriptor: | DNA damage-responsive transcriptional repressor RPH1 | | Authors: | Chang, Y, Wu, J, Tong, X, Zhou, J, Ding, J. | | Deposit date: | 2010-09-02 | | Release date: | 2010-12-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism
Biochem.J., 433, 2011
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2DSB
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3NFP
 | | Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain | | Descriptor: | Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab | | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | | Deposit date: | 2010-06-10 | | Release date: | 2010-09-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab
Cell Res., 20, 2010
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2DSC
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6LPU
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with L-2-hydroxyglutarate (L-2-HG) | | Descriptor: | (2S)-2-HYDROXYPENTANEDIOIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | | Authors: | Yang, J, Zhu, H, Ding, J. | | Deposit date: | 2020-01-12 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.923 Å) | | Cite: | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
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6LPQ
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-malate (D-MAL) | | Descriptor: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, D-MALATE, ... | | Authors: | Yang, J, Zhu, H, Ding, J. | | Deposit date: | 2020-01-12 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
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6LPN
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in apo form | | Descriptor: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Yang, J, Zhu, H, Ding, J. | | Deposit date: | 2020-01-12 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.206 Å) | | Cite: | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
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4HJW
 | | Crystal structure of Metarhizium anisopliae IDCase in apo form | | Descriptor: | Uracil-5-carboxylate decarboxylase, ZINC ION | | Authors: | Xu, S, Zhu, J, Ding, J. | | Deposit date: | 2012-10-14 | | Release date: | 2013-09-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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3NFS
 | | Crystal structure the Fab fragment of therapeutic antibody daclizumab | | Descriptor: | Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab | | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | | Deposit date: | 2010-06-10 | | Release date: | 2010-09-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab
Cell Res., 20, 2010
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4FG7
 | | Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-293 in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1 | | Authors: | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | | Deposit date: | 2012-06-04 | | Release date: | 2013-01-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
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3W8H
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4ZBP
 | | Crystal structure of the AMPCPR-bound AtNUDT7 | | Descriptor: | ALPHA-BETA METHYLENE ADP-RIBOSE, Nudix hydrolase 7, SULFATE ION | | Authors: | Tang, Q, Liu, C, Zhong, C, Ding, J. | | Deposit date: | 2015-04-15 | | Release date: | 2015-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation.
Mol Plant, 8, 2015
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3OXF
 | | Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I) | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION | | Authors: | Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J. | | Deposit date: | 2010-09-21 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
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5GS9
 | | Crystal structure of CASTOR1-arginine | | Descriptor: | ARGININE, GATS-like protein 3 | | Authors: | Zhang, T, Ding, J. | | Deposit date: | 2016-08-15 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling.
Cell Discov, 2, 2016
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5H48
 | | Crystal structure of Cbln1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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5H4C
 | | Crystal structure of Cbln4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Cbln4 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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5H49
 | | Crystal structure of Cbln1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | Authors: | Zhong, C, Shen, J, Zhang, H, Ding, J. | | Deposit date: | 2016-10-31 | | Release date: | 2017-09-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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3W8I
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3OXL
 | | Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form II) | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION | | Authors: | Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J. | | Deposit date: | 2010-09-21 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding
Nucleic Acids Res., 39, 2011
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2AKE
 | | Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) | | Descriptor: | SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ... | | Authors: | Shen, N, Guo, L, Yang, B, Jin, Y, Ding, J. | | Deposit date: | 2005-08-03 | | Release date: | 2006-07-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
Nucleic Acids Res., 34, 2006
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3OXG
 | | human lysine methyltransferase Smyd3 in complex with AdoHcy (Form III) | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION | | Authors: | Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J. | | Deposit date: | 2010-09-21 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
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5GK9
 | | Crystal structure of human HBO1 in complex with BRPF2 | | Descriptor: | ACETYL COENZYME *A, BRD1 protein, Histone acetyltransferase KAT7, ... | | Authors: | Tao, Y, Zhu, J, Xu, S, Ding, J. | | Deposit date: | 2016-07-04 | | Release date: | 2017-03-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2.
Nucleic Acids Res., 45, 2017
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