5J43
 
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6CP8
 | | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CdiA, CdiI, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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8PQQ
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5HKQ
 | | Crystal structure of CDI complex from Escherichia coli STEC_O31 | | 分子名称: | CdiI immunity protein, Contact-dependent inhibitor A | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-01-14 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-03-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional plasticity of antibacterial EndoU toxins.
Mol.Microbiol., 109, 2018
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6CP9
 | | Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342 | | 分子名称: | CdiA, CdiI | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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8PZ0
 | | Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14. | | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, CHLORIDE ION, ... | | 著者 | Simpson, M.C, Czekster, C.M, Harding, C.J. | | 登録日 | 2023-07-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
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8PZM
 | | Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 bound to bestatin inhibitor and manganese | | 分子名称: | 1,2-ETHANEDIOL, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, BICARBONATE ION, ... | | 著者 | Simpson, M.C, Czekster, C.M, Harding, C.J. | | 登録日 | 2023-07-27 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
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8PZY
 | | Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 - hexameric assembly with manganese bound | | 分子名称: | 1,2-ETHANEDIOL, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, AMMONIUM ION, ... | | 著者 | Simpson, M.C, Czekster, C.M, Harding, C.J. | | 登録日 | 2023-07-27 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase.
Biochemistry, 62, 2023
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6TAB
 | | Bd0314 DslA wild-type form 2 | | 分子名称: | SLT domain-containing protein, SULFATE ION | | 著者 | Lovering, A.L, Harding, C.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus.
Nat Commun, 11, 2020
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8PQR
 | | Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to DAD_Immucillin-H | | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Nucleoside 2-deoxyribosyltransferase | | 著者 | Tang, P, Harding, C.J, Czekster, C.M. | | 登録日 | 2023-07-11 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.586 Å) | | 主引用文献 | Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
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6TAF
 | | Bd0314 DslA E154Q mutant | | 分子名称: | ACETATE ION, SLT domain-containing protein, SULFATE ION | | 著者 | Lovering, A.L, Harding, C.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.336 Å) | | 主引用文献 | A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus.
Nat Commun, 11, 2020
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6TA9
 | | Bd0314 DslA wild-type form 1 | | 分子名称: | SLT domain-containing protein, SULFATE ION | | 著者 | Lovering, A.L, Harding, C.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.361 Å) | | 主引用文献 | A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus.
Nat Commun, 11, 2020
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5E3E
 | | Crystal structure of CdiA-CT/CdiI complex from Y. kristensenii 33638 | | 分子名称: | CdiI immunity protein, Large exoprotein involved in heme utilization or adhesion, SODIUM ION | | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-10-02 | | 公開日 | 2015-11-25 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily.
Nucleic Acids Res., 45, 2017
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7KW7
 | | Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... | | 著者 | Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. | | 登録日 | 2020-11-30 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.
Nature, 601, 2022
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6TAD
 | | Bd0314 DslA E143Q mutant | | 分子名称: | SLT domain-containing protein | | 著者 | Lovering, A.L, Harding, C.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-10-07 | | 実験手法 | X-RAY DIFFRACTION (1.822 Å) | | 主引用文献 | A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus.
Nat Commun, 11, 2020
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8PQP
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8PQT
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8PQS
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6N55
 | | Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidouridine | | 分子名称: | 2'-azido-2'-deoxyuridine, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Cuthbert, B.J, Nainar, S, Spitale, R.C, Goulding, C.W. | | 登録日 | 2018-11-21 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.085 Å) | | 主引用文献 | An optimized chemical-genetic method for cell-specific metabolic labeling of RNA.
Nat.Methods, 17, 2020
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5T87
 | | Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424 | | 分子名称: | CdiA toxin, CdiI immunity protein | | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1, 2018
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6N53
 | | Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidouridine monophosphate | | 分子名称: | 2'-deoxy-2'-triaza-1,2-dien-2-ium-1-yl-uridine-5'-monophosphate, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cuthbert, B.J, Nainar, S, Spitale, R.C, Goulding, C.W. | | 登録日 | 2018-11-21 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | An optimized chemical-genetic method for cell-specific metabolic labeling of RNA.
Nat.Methods, 17, 2020
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6N54
 | | Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidocytidine monophosphate | | 分子名称: | 2'-azido-2'-deoxycytidine 5'-(dihydrogen phosphate), GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cuthbert, B.J, Nainar, S, Spitale, R.C, Goulding, C.W. | | 登録日 | 2018-11-21 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.424 Å) | | 主引用文献 | An optimized chemical-genetic method for cell-specific metabolic labeling of RNA.
Nat.Methods, 17, 2020
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5T86
 | | Crystal structure of CDI complex from E. coli A0 34/86 | | 分子名称: | ACETATE ION, CdiA toxin, CdiI immunity protein | | 著者 | Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of CDI complex from E. coli A0 34/86
To Be Published
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5FFP
 | | Crystal structure of CdiI from Burkholderia dolosa AUO158 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Immunity 23 family protein | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2015-12-18 | | 公開日 | 2016-01-20 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of CdiI from Burkholderia dolosa AUO158
To Be Published
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4G6V
 | | CdiA-CT/CdiI toxin and immunity complex from Burkholderia pseudomallei | | 分子名称: | Adhesin/hemolysin, BROMIDE ION, CdiI | | 著者 | Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W. | | 登録日 | 2012-07-19 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
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