5T87

Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424

Summary for 5T87

• Entry DOI: 10.2210/pdb5t87/pdb
• Related: 5T86
• Descriptor: CdiI immunity protein, CdiA toxin (3 entities in total)
• Functional Keywords: contact-dependent growth inhibition, toxin, antitoxin, immunity protein, structural genomics, psi-biology, midwest center for structural genomics, mcsg, structure-function analysis of polymorphic cdi toxin-immunity protein complexes, uc4cdi
• Biological source: Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1); More
• Total number of polymer chains: 8
• Total formula weight: 86349.34

Authors

Michalska, K.,Joachimiak, G.,Jedrzejczak, R.,Hayes, C.S.,Goulding, C.W.,Joachimiak, A.,Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI),Midwest Center for Structural Genomics (MCSG) (deposition date: 2016-09-06, release date: 2017-09-13, Last modification date: 2024-10-09)

Primary citation

Kryshtafovych, A.,Albrecht, R.,Basle, A.,Bule, P.,Caputo, A.T.,Carvalho, A.L.,Chao, K.L.,Diskin, R.,Fidelis, K.,Fontes, C.M.G.A.,Fredslund, F.,Gilbert, H.J.,Goulding, C.W.,Hartmann, M.D.,Hayes, C.S.,Herzberg, O.,Hill, J.C.,Joachimiak, A.,Kohring, G.W.,Koning, R.I.,Lo Leggio, L.,Mangiagalli, M.,Michalska, K.,Moult, J.,Najmudin, S.,Nardini, M.,Nardone, V.,Ndeh, D.,Nguyen, T.H.,Pintacuda, G.,Postel, S.,van Raaij, M.J.,Roversi, P.,Shimon, A.,Singh, A.K.,Sundberg, E.J.,Tars, K.,Zitzmann, N.,Schwede, T.
Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1:27-50, 2018

PubMed Abstract: The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.

PubMed: 28960539
DOI: 10.1002/prot.25392

Experimental method

X-RAY DIFFRACTION (2.4 Å)