8CJW
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![BU of 8cjw by Molmil](/molmil-images/mine/8cjw) | Nucleoprotein Thogotovirus delta188-196 | Descriptor: | 1,2-ETHANEDIOL, Nucleoprotein, PHOSPHATE ION, ... | Authors: | Dick, A, Roske, Y. | Deposit date: | 2023-02-13 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly. Structure, 2024
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4RV7
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![BU of 4rv7 by Molmil](/molmil-images/mine/4rv7) | Characterization of an essential diadenylate cyclase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Diadenylate cyclase, HEXANE-1,6-DIOL, ... | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2014-11-25 | Release date: | 2015-01-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA from Listeria monocytogenes. J.Biol.Chem., 290, 2015
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4RLE
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![BU of 4rle by Molmil](/molmil-images/mine/4rle) | Crystal structure of the c-di-AMP binding PII-like protein DarA | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, NICKEL (II) ION, Uncharacterized protein YaaQ | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2014-10-16 | Release date: | 2014-12-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA. J.Biol.Chem., 290, 2015
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2VCG
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![BU of 2vcg by Molmil](/molmil-images/mine/2vcg) | Crystal structure of a HDAC-like protein HDAH from Bordetella sp. with the bound inhibitor ST-17 | Descriptor: | CHLORIDE ION, GLYCEROL, HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE, ... | Authors: | Dickmanns, A, Strasser, A, Ficner, R. | Deposit date: | 2007-09-24 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Phenylalanine-Containing Hydroxamic Acids as Selective Inhibitors of Class Iib Histone Deacetylases (Hdacs). Bioorg.Med.Chem., 16, 2008
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3OGZ
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![BU of 3ogz by Molmil](/molmil-images/mine/3ogz) | Protein structure of USP from L. major in Apo-form | Descriptor: | GLYCEROL, UDP-sugar pyrophosphorylase | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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3OH2
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![BU of 3oh2 by Molmil](/molmil-images/mine/3oh2) | Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-GALACTOSE | Descriptor: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, GLYCEROL, UDP-sugar pyrophosphorylase | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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3OH3
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![BU of 3oh3 by Molmil](/molmil-images/mine/3oh3) | Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE -Arabinose | Descriptor: | GLYCEROL, UDP-sugar pyrophosphorylase, [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl dihydrogen diphosphate | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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3OH4
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![BU of 3oh4 by Molmil](/molmil-images/mine/3oh4) | Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE Glucose | Descriptor: | GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F.H, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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3OH1
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![BU of 3oh1 by Molmil](/molmil-images/mine/3oh1) | Protein structure of USP from L. major bound to URIDINE-5'-DIPHOSPHATE-Galacturonic acid | Descriptor: | (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, GLYCEROL, UDP-sugar pyrophosphorylase | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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3OH0
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![BU of 3oh0 by Molmil](/molmil-images/mine/3oh0) | Protein structure of USP from L. major bound to URIDINE-5'-TRIPHOSPHATE | Descriptor: | GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE 5'-TRIPHOSPHATE | Authors: | Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. | Deposit date: | 2010-08-17 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
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1Y4J
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![BU of 1y4j by Molmil](/molmil-images/mine/1y4j) | Crystal structure of the paralogue of the human formylglycine generating enzyme | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Dickmanns, A, Rudolph, M.G, Ficner, R. | Deposit date: | 2004-12-01 | Release date: | 2005-02-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.864 Å) | Cite: | Crystal Structure of Human pFGE, the Paralog of the C{alpha}-formylglycine-generating Enzyme J.Biol.Chem., 280, 2005
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6F2C
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![BU of 6f2c by Molmil](/molmil-images/mine/6f2c) | Methylglyoxal synthase MgsA from Bacillus subtilis | Descriptor: | CHLORIDE ION, GLYCEROL, Methylglyoxal synthase | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2017-11-24 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh inBacillus subtilis. J. Biol. Chem., 293, 2018
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2B5D
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![BU of 2b5d by Molmil](/molmil-images/mine/2b5d) | Crystal structure of the novel alpha-amylase AmyC from Thermotoga maritima | Descriptor: | alpha-Amylase | Authors: | Dickmanns, A, Ballschmiter, M, Liebl, W, Ficner, R. | Deposit date: | 2005-09-28 | Release date: | 2006-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the novel alpha-amylase AmyC from Thermotoga maritima. Acta Crystallogr.,Sect.D, 62, 2006
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8RYT
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![BU of 8ryt by Molmil](/molmil-images/mine/8ryt) | Structural characterization of Thogoto Virus nucleoprotein provides insights into RNA encapsidation and assembly | Descriptor: | Nucleoprotein | Authors: | Roske, Y, Mikirtumov, V, Daumke, O, Kudryashev, M, Dick, A. | Deposit date: | 2024-02-09 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (18 Å) | Cite: | Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly. Structure, 2024
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4N6Q
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![BU of 4n6q by Molmil](/molmil-images/mine/4n6q) | Crystal structure of VosA velvet domain | Descriptor: | IODIDE ION, NITRATE ION, VosA | Authors: | Ahmed, Y.L, Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2013-10-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-kappa B. Plos Biol., 11, 2013
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3FBX
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![BU of 3fbx by Molmil](/molmil-images/mine/3fbx) | Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Lakomek, K, Dickmanns, A, Mueller, U, Ficner, R. | Deposit date: | 2008-11-20 | Release date: | 2009-03-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse Acta Crystallogr.,Sect.D, 65, 2009
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3FGW
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![BU of 3fgw by Molmil](/molmil-images/mine/3fgw) | One chain form of the 66.3 kDa protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, IODIDE ION, ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2008-12-08 | Release date: | 2009-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography Bmc Struct.Biol., 9, 2009
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3FGR
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![BU of 3fgr by Molmil](/molmil-images/mine/3fgr) | Two chain form of the 66.3 kDa protein at 1.8 Angstroem | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2008-12-08 | Release date: | 2009-09-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography Bmc Struct.Biol., 9, 2009
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8ARU
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![BU of 8aru by Molmil](/molmil-images/mine/8aru) | |
3EWI
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![BU of 3ewi by Molmil](/molmil-images/mine/3ewi) | Structural analysis of the C-terminal domain of murine CMP-Sialic acid Synthetase | Descriptor: | N-acylneuraminate cytidylyltransferase | Authors: | Oschlies, M, Dickmanns, A, Stummeyer, K, Gerardy-Schahn, R, Ficner, R, Muenster-Kuehnel, A.K. | Deposit date: | 2008-10-15 | Release date: | 2009-08-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme. J.Mol.Biol., 393, 2009
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5J8N
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![BU of 5j8n by Molmil](/molmil-images/mine/5j8n) | |
4HZK
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![BU of 4hzk by Molmil](/molmil-images/mine/4hzk) | |
1XK5
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![BU of 1xk5 by Molmil](/molmil-images/mine/1xk5) | Crystal structure of the m3G-cap-binding domain of snurportin1 in complex with a m3GpppG-cap dinucleotide | Descriptor: | 2,2,7-TRIMETHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, snurportin-1 | Authors: | Strasser, A, Dickmanns, A, Luehrmann, R, Ficner, R. | Deposit date: | 2004-09-27 | Release date: | 2005-06-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1 Embo J., 24, 2005
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1ZZ1
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![BU of 1zz1 by Molmil](/molmil-images/mine/1zz1) | Crystal structure of a HDAC-like protein with SAHA bound | Descriptor: | Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | Deposit date: | 2005-06-13 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
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1ZZ0
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![BU of 1zz0 by Molmil](/molmil-images/mine/1zz0) | Crystal structure of a HDAC-like protein with acetate bound | Descriptor: | ACETATE ION, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | Deposit date: | 2005-06-13 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
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