3NRU
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![BU of 3nru by Molmil](/molmil-images/mine/3nru) | Ligand binding domain of EPHA7 | Descriptor: | CHLORIDE ION, Ephrin receptor, SULFATE ION | Authors: | Walker, J.R, Yermekbayeva, L, Seitova, A, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S. | Deposit date: | 2010-06-30 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ephrin A7 ligand binding domain To be Published
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3L11
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![BU of 3l11 by Molmil](/molmil-images/mine/3l11) | Crystal Structure of the Ring Domain of RNF168 | Descriptor: | E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION | Authors: | Neculai, D, Yermekbayeva, L, Crombet, L, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-12-10 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. J.Biol.Chem., 287, 2012
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3JYU
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![BU of 3jyu by Molmil](/molmil-images/mine/3jyu) | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitin carboxyl-terminal hydrolase | Authors: | Bacik, J.P, Avvakumov, G, Walker, J.R, Xue, S, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-22 | Release date: | 2009-10-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) To be Published
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3P1I
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![BU of 3p1i by Molmil](/molmil-images/mine/3p1i) | Ligand binding domain of human ephrin type-B receptor 3 | Descriptor: | CHLORIDE ION, Ephrin type-B receptor 3, SULFATE ION | Authors: | Walker, J.R, Yermekbayeva, L, Seitova, A, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-09-30 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ligand Binding Domain of Human Ephb3 To be Published
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3PPA
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![BU of 3ppa by Molmil](/molmil-images/mine/3ppa) | Structure of the Dusp-Ubl domains of Usp15 | Descriptor: | CITRIC ACID, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Walker, J.R, Asinas, A.E, Dong, A, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-11-24 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of the Dusp-Ubl Domains of the Ubiquitin-Specific Protease 15 To be Published
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3KUL
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![BU of 3kul by Molmil](/molmil-images/mine/3kul) | Kinase domain of human ephrin type-A receptor 8 (EPHA8) | Descriptor: | BETA-MERCAPTOETHANOL, Ephrin type-A receptor 8, GLYCEROL, ... | Authors: | Walker, J.R, Yermekbayeva, L, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-27 | Release date: | 2009-12-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Kinase Domain of Human Ephrin Type-A Receptor 8 (Epha8) To be Published
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3Q1D
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![BU of 3q1d by Molmil](/molmil-images/mine/3q1d) | The B-box domain of Trim54 | Descriptor: | Tripartite motif-containing protein 54, ZINC ION | Authors: | Walker, J.R, Yermekbayeva, L, Mackenzie, F, Dong, A, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S. | Deposit date: | 2010-12-17 | Release date: | 2011-01-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The B-Box Domain of Trim54 To be Published
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3PFY
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![BU of 3pfy by Molmil](/molmil-images/mine/3pfy) | The catalytic domain of human OTUD5 | Descriptor: | DI(HYDROXYETHYL)ETHER, OTU domain-containing protein 5, SULFATE ION, ... | Authors: | Walker, J.R, Asinas, A.E, Crombet, L, Dong, A, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-10-29 | Release date: | 2010-12-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | The catalytic domain of human OTUD5 To be Published
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3KCI
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![BU of 3kci by Molmil](/molmil-images/mine/3kci) | The third RLD domain of HERC2 | Descriptor: | Probable E3 ubiquitin-protein ligase HERC2 | Authors: | Walker, J.R, Qiu, L, Vesterberg, A, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S. | Deposit date: | 2009-10-21 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the Third RLD Domain of Herc2 To be Published
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3KKA
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![BU of 3kka by Molmil](/molmil-images/mine/3kka) | Co-crystal structure of the sam domains of EPHA1 AND EPHA2 | Descriptor: | CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2 | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2 To be Published
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3PG6
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![BU of 3pg6 by Molmil](/molmil-images/mine/3pg6) | The carboxyl terminal domain of human deltex 3-like | Descriptor: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase DTX3L, ... | Authors: | Walker, J.R, Obiero, J, Kania, J, Schuler, H, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-10-30 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fold of the conserved DTC domain in Deltex proteins. Proteins, 80, 2012
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3K0W
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![BU of 3k0w by Molmil](/molmil-images/mine/3k0w) | Crystal structure of the tandem IG-like C2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Descriptor: | CHLORIDE ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, isoform 2 | Authors: | Walker, J.R, Qiu, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-25 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Tandem Ig-Like C2-Type 2 Domains of the Human Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1. To be Published
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3I3T
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![BU of 3i3t by Molmil](/molmil-images/mine/3i3t) | Crystal structure of covalent ubiquitin-USP21 complex | Descriptor: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 21, ... | Authors: | Neculai, D, Avvakumov, G.V, Walker, J.R, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-06-30 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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3MBW
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![BU of 3mbw by Molmil](/molmil-images/mine/3mbw) | Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1 | Descriptor: | Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ... | Authors: | Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-26 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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3MX0
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![BU of 3mx0 by Molmil](/molmil-images/mine/3mx0) | Crystal Structure of EphA2 ectodomain in complex with ephrin-A5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ... | Authors: | Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S. | Deposit date: | 2010-05-06 | Release date: | 2010-06-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.506 Å) | Cite: | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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3LMN
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![BU of 3lmn by Molmil](/molmil-images/mine/3lmn) | Oligomeric structure of the DUSP domain of human USP15 | Descriptor: | ACETIC ACID, FORMIC ACID, Ubiquitin carboxyl-terminal hydrolase 15 | Authors: | Walker, J.R, Asinas, A, Avvakumov, G.V, Alenkin, D, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S. | Deposit date: | 2010-01-31 | Release date: | 2010-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of the Human Ubiquitin-Specific Protease 15 DUSP Domain To be Published
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3RQR
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![BU of 3rqr by Molmil](/molmil-images/mine/3rqr) | Crystal structure of the RYR domain of the rabbit ryanodine receptor | Descriptor: | (UNK)(UNK)(UNK)(UNK), Ryanodine receptor 1 | Authors: | Nair, U.B, Li, W, Dong, A, Walker, J.R, Gramolini, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2011-04-28 | Release date: | 2011-06-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structural determination of the phosphorylation domain of the ryanodine receptor. Febs J., 279, 2012
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3L4H
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![BU of 3l4h by Molmil](/molmil-images/mine/3l4h) | Helical box domain and second WW domain of the human E3 ubiquitin-protein ligase HECW1 | Descriptor: | ACETIC ACID, E3 ubiquitin-protein ligase HECW1 | Authors: | Walker, J.R, Qiu, L, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-12-20 | Release date: | 2010-05-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The tandem helical box and second WW domains of human HECW1 To be Published
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1YLA
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![BU of 1yla by Molmil](/molmil-images/mine/1yla) | Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2) | Descriptor: | Ubiquitin-conjugating enzyme E2-25 kDa | Authors: | Choe, J, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-01-19 | Release date: | 2005-02-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285, 2010
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3FL2
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![BU of 3fl2 by Molmil](/molmil-images/mine/3fl2) | Crystal structure of the ring domain of the E3 ubiquitin-protein ligase UHRF1 | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-18 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the Ring Domain of the E3 Ubiquitin-Protein Ligase Uhrf1 To be Published
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1ZDN
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![BU of 1zdn by Molmil](/molmil-images/mine/1zdn) | Ubiquitin-conjugating enzyme E2S | Descriptor: | SODIUM ION, Ubiquitin-conjugating enzyme E2S | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-04-14 | Release date: | 2005-05-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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3H8H
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![BU of 3h8h by Molmil](/molmil-images/mine/3h8h) | Structure of the C-terminal domain of human RNF2/RING1B; | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase RING2, GLYCEROL, ... | Authors: | Walker, J.R, Bezsonova, I, Bacik, J, Duan, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-04-29 | Release date: | 2009-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins. Biochemistry, 48, 2009
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1ZUO
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![BU of 1zuo by Molmil](/molmil-images/mine/1zuo) | Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation | Descriptor: | BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912 | Authors: | Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-05-31 | Release date: | 2005-07-05 | Last modified: | 2012-11-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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3CLZ
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![BU of 3clz by Molmil](/molmil-images/mine/3clz) | The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA | Descriptor: | 5'-D(*DCP*DCP*DCP*DTP*DGP*DCP*DGP*DGP*DGP*DCP*DCP*DC)-3', 5'-D(*DGP*DGP*DGP*DCP*DCP*(5CM)P*DGP*DCP*DAP*DGP*DGP*DG)-3', E3 ubiquitin-protein ligase UHRF1 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-03-20 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature, 455, 2008
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3BZH
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![BU of 3bzh by Molmil](/molmil-images/mine/3bzh) | Crystal structure of human ubiquitin-conjugating enzyme E2 E1 | Descriptor: | GLYCEROL, Ubiquitin-conjugating enzyme E2 E1 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-18 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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