1BWP
 
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | Deposit date: | 1998-09-27 | | Release date: | 1999-05-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
|
|
1CC0
 | | CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... | | Authors: | Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | | Deposit date: | 1999-03-03 | | Release date: | 2000-01-07 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
5TGL
 | | A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX | | Descriptor: | LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER | | Authors: | Brzozowski, A.M, Derewenda, U, Derewenda, Z.S, Dodson, G.G, Lawson, D, Turkenburg, J.P, Bjorkling, F, Huge-Jensen, B, Patkar, S.R, Thim, L. | | Deposit date: | 1991-10-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351, 1991
|
|
3MSX
 | | Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ... | | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2010-04-29 | | Release date: | 2011-03-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
To be Published
|
|
3N77
 | | Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2 | | Descriptor: | Nucleoside triphosphatase nudI | | Authors: | Frydrysiak, J, Cooper, D.R, Derewenda, U, Anderson, W.F, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI), Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2010-05-26 | | Release date: | 2010-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2
To be Published
|
|
3FMS
 | | Crystal structure of TM0439, a GntR transcriptional regulator | | Descriptor: | ACETATE ION, NICKEL (II) ION, Transcriptional regulator, ... | | Authors: | Zheng, M, Cooper, D.R, Yu, M, Hung, L.-W, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2008-12-22 | | Release date: | 2009-02-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
|
|
1ZNJ
 | | INSULIN, MONOCLINIC CRYSTAL FORM | | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Turkenburg, J.P, Dodson, G.G, Derewenda, U, Smith, G.D, Dodson, E.J, Derewenda, Z.S, Xiao, B. | | Deposit date: | 1997-09-23 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
|
|
1JKM
 | | BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE | | Descriptor: | BREFELDIN A ESTERASE | | Authors: | Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S. | | Deposit date: | 1998-02-04 | | Release date: | 1999-02-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Nat.Struct.Biol., 6, 1999
|
|
2BQQ
 | | X-ray Structure of the N-terminal Domain of Human Doublecortin | | Descriptor: | NEURONAL MIGRATION PROTEIN DOUBLECORTIN | | Authors: | Kim, M.H, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2005-04-27 | | Release date: | 2006-07-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Dc-Module of Doublecortin: Dynamics, Domain Boundaries, and Functional Implications.
Proteins, 64, 2006
|
|
1MJD
 | | Structure of N-terminal domain of human doublecortin | | Descriptor: | DOUBLECORTIN | | Authors: | Kim, M.H, Cierpicki, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z.S. | | Deposit date: | 2002-08-27 | | Release date: | 2003-04-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
|
|
5VIM
 | |
5VKD
 | | Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | | Descriptor: | Fab Heavy Chain, Fab light chain, Nucleoprotein | | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | | Deposit date: | 2017-04-21 | | Release date: | 2018-04-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
|
|
5VZ1
 | | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | | Descriptor: | Apo Antibody Fab Heavy Chain, Apo Antibody Fab Light Chain, ZINC ION | | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | | Deposit date: | 2017-05-26 | | Release date: | 2018-06-27 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.112 Å) | | Cite: | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
|
|
5VI7
 | |
5W2B
 | | Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment | | Descriptor: | Fab Heavy Chain, Fab Light Chain, Nucleoprotein | | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | | Deposit date: | 2017-06-06 | | Release date: | 2018-06-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
|
|
1MFW
 | | STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN | | Descriptor: | DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION | | Authors: | Kim, M.H, Cierpickil, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z. | | Deposit date: | 2002-08-13 | | Release date: | 2003-04-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
|
|
1VZY
 | | Crystal structure of the Bacillus subtilis HSP33 | | Descriptor: | 33 KDA CHAPERONIN, ACETATE ION, ZINC ION | | Authors: | Janda, I.K, Devedjiev, Y, Derewenda, U, Dauter, Z, Bielnicki, J, Cooper, D.R, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-05-29 | | Release date: | 2004-10-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism.
Structure, 12, 2004
|
|
1MG4
 | | STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: WILD TYPE PROTEIN | | Descriptor: | DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION | | Authors: | Kim, M.H, Cierpickil, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z. | | Deposit date: | 2002-08-14 | | Release date: | 2003-04-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.504 Å) | | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
|
|
1OBZ
 | | Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha peptide. | | Descriptor: | ACETATE ION, INTERLEUKIN 5 RECEPTOR ALPHA, SYNTENIN 1 | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-31 | | Release date: | 2003-07-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
|
|
1OBY
 | | Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. | | Descriptor: | SULFATE ION, SYNDECAN-4, SYNTENIN 1 | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-31 | | Release date: | 2003-07-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
|
|
1OBX
 | | Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. | | Descriptor: | COBALT (II) ION, INTERLEUKIN 5 RECEPTOR ALPHA, SULFATE ION, ... | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-31 | | Release date: | 2003-07-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
|
|
1E0W
 | | Xylanase 10A from Sreptomyces lividans. native structure at 1.2 angstrom resolution | | Descriptor: | ENDO-1,4-BETA-XYLANASE A | | Authors: | Ducros, V, Charnock, S.J, Derewenda, U, Derewenda, Z.S, Dauter, Z, Dupont, C, Shareck, F, Morosoli, R, Kluepfel, D, Davies, G.J. | | Deposit date: | 2000-04-10 | | Release date: | 2001-04-05 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
J.Biol.Chem., 275, 2000
|
|
1N99
 | | CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN | | Descriptor: | Syntenin 1 | | Authors: | Kang, B.S, Cooper, D.R, Jelen, F, Devedjiev, Y, Derewenda, U, Dauter, Z, Otlewski, J, Derewenda, Z.S. | | Deposit date: | 2002-11-22 | | Release date: | 2003-04-15 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties
Structure, 11, 2003
|
|
1NTE
 | | CRYSTAL STRUCTURE ANALYSIS OF THE SECOND PDZ DOMAIN OF SYNTENIN | | Descriptor: | OXYGEN ATOM, Syntenin 1 | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-29 | | Release date: | 2003-07-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm.
Structure, 11, 2003
|
|
1KMZ
 | | MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE | | Descriptor: | mitomycin-binding protein | | Authors: | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | | Deposit date: | 2001-12-17 | | Release date: | 2002-07-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
|
|
