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PDB: 16 件
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
著者De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2017-09-15
公開日2018-08-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
8YT4
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BU of 8yt4 by Molmil
Structure of Aquifex aeolicus Lumazine Synthase by Cryo-Electron Microscopy to 1.42 Angstrom Resolution
分子名称: 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION
著者Savva, C.G, Sobhy, M.A, De Biasio, A, Hamdan, S.M.
登録日2024-03-24
公開日2024-04-10
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (1.42 Å)
主引用文献Structure of Aquifex aeolicus lumazine synthase by cryo-electron microscopy to 1.42 angstrom resolution.
Iucrj, 11, 2024
7QNZ
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BU of 7qnz by Molmil
human Lig1-DNA-PCNA complex reconstituted in absence of ATP
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.58 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
7QO1
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BU of 7qo1 by Molmil
complex of DNA ligase I and FEN1 on PCNA and DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
8B8T
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BU of 8b8t by Molmil
Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP
分子名称: DNA ligase 1, Proliferating cell nuclear antigen
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2022-10-05
公開日2023-01-11
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
著者De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-05-15
公開日2018-05-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
著者Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
登録日2018-10-11
公開日2019-01-23
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
6GWS
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BU of 6gws by Molmil
Crystal structure of human PCNA in complex with three p15 peptides
分子名称: PCNA-associated factor, Proliferating cell nuclear antigen
著者De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-06-25
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
7NV1
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BU of 7nv1 by Molmil
Human Pol Kappa holoenzyme with Ub-PCNA
分子名称: DNA Primer, DNA Template, DNA polymerase kappa, ...
著者Lancey, C, De Biasio, A, Hamdan, S.M.
登録日2021-03-15
公開日2021-11-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.
Nat Commun, 12, 2021
7NV0
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BU of 7nv0 by Molmil
Human Pol Kappa holoenzyme with wt PCNA
分子名称: DNA Primer, DNA Template, DNA polymerase kappa, ...
著者Lancey, C, De Biasio, A, Hamdan, S.M.
登録日2021-03-15
公開日2021-11-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.
Nat Commun, 12, 2021
3OP8
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BU of 3op8 by Molmil
Crystal structure of the domain V from beta2-glycoprotein I
分子名称: Beta-2-glycoprotein 1, SULFATE ION
著者Kolyada, A, Lee, C.-J, De Biasio, A, Beglova, N.
登録日2010-08-31
公開日2011-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome.
Plos One, 5, 2010
6S1O
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BU of 6s1o by Molmil
Human polymerase delta holoenzyme Conformer 3
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
6S1N
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BU of 6s1n by Molmil
Human polymerase delta holoenzyme Conformer 2
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.86 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
6S1M
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BU of 6s1m by Molmil
Human polymerase delta holoenzyme Conformer 1
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
6TNZ
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BU of 6tnz by Molmil
Human polymerase delta-FEN1-PCNA toolbelt
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-12-10
公開日2019-12-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
6TNY
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BU of 6tny by Molmil
Processive human polymerase delta holoenzyme
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-12-10
公開日2019-12-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020

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件を2024-10-30に公開中

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