8OG3
 
 | | E. coli NfsB triple mutant T41L/N71S/F124T bound to citrate | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | | 登録日 | 2023-03-17 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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8AJX
 | | E. coli NfsA with Fumarate | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, FUMARIC ACID, ... | | 著者 | Day, M.A, Jarrom, D, White, S.A, Hyde, E.I. | | 登録日 | 2022-07-28 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Oxygen-insensitive nitroreductase E. coli NfsA, but not NfsB, is inhibited by fumarate.
Proteins, 91, 2023
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8C5P
 | | E. coli NfsB mutant N71S T41L with acetate | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Day, M.A, White, S.A, Hyde, E.I. | | 登録日 | 2023-01-10 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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8CCV
 | | E. coli NfsB mutant T41LN71S with nicotinate | | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | | 登録日 | 2023-01-27 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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7Z0W
 | | E. coli NfsA bound to NADP+ | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | | 登録日 | 2022-02-23 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
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8CJ0
 | | E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-02-11 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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8C5E
 | | E. coli NfsB-T41Q/N71S/F124T mutant bound to nicotinic acid | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-01-06 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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8C5F
 | | E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-01-07 | | 公開日 | 2023-04-19 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
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7Q0O
 | | E. coli NfsA | | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NADPH nitroreductase | | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | | 登録日 | 2021-10-15 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
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