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PDB: 105 件

3UBY
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Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA
分子名称: DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3'), DNA-3-methyladenine glycosylase
著者Setser, J.W, Lingaraju, G.M, Davis, C.A, Samson, L.D, Drennan, C.L.
登録日2011-10-25
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.
Biochemistry, 51, 2012
5HM6
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N-terminal domain of BfmR from Acinetobacter baumannii
分子名称: BfmR
著者Roth, B.R, Davies, C.
登録日2016-01-15
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.
J. Mol. Biol., 2018
1BJA
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ACTIVATION DOMAIN OF THE PHAGE T4 TRANSCRIPTION FACTOR MOTA
分子名称: SULFATE ION, TRANSCRIPTION REGULATORY PROTEIN MOTA
著者Finnin, M.S, Cicero, M.P, Davies, C, Porter, S.J, White, S.W, Kreuzer, K.N.
登録日1998-06-23
公開日1998-11-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The activation domain of the MotA transcription factor from bacteriophage T4.
EMBO J., 16, 1997
1NZU
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Wild-type penicillin-binding protein 5 from E. coli modified by beta-mercaptoethanol
分子名称: BETA-MERCAPTOETHANOL, Penicillin-binding protein 5
著者Nicola, G, Nicholas, R.A, Davies, C.
登録日2003-02-19
公開日2004-03-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.
Biochem.J., 392, 2005
3LO7
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Crystal structure of PBPA from Mycobacterium tuberculosis
分子名称: Penicillin-binding protein A
著者Fedarovich, A, Davies, C.
登録日2010-02-03
公開日2010-03-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis.
J.Mol.Biol., 398, 2010
6C4T
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Staphylopine dehydrogenase (SaODH) - NADP+ bound
分子名称: GLYCEROL, Staphylopine dehydrogenase, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者McFarlane, J.S, Davis, C.L, Lamb, A.L.
登録日2018-01-12
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase.
J. Biol. Chem., 293, 2018
6C4L
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Yersinopine dehydrogenase (YpODH) - Apo
分子名称: Yersinopine dehydrogenase
著者McFarlane, J.S, Davis, C.L, Lamb, A.L.
登録日2018-01-12
公開日2018-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase.
J. Biol. Chem., 293, 2018
6VBD
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Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone
分子名称: CEFOTAXIME, C3' cleaved, open, ...
著者Singh, A, Davies, C.
登録日2019-12-18
公開日2020-04-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
2F1D
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X-Ray Structure of imidazoleglycerol-phosphate dehydratase
分子名称: Imidazoleglycerol-phosphate dehydratase 1, MANGANESE (II) ION, SULFATE ION
著者Rice, D.W, Glynn, S.E, Baker, P.J, Sedelnikova, S.E, Davies, C.L, Eadsforth, T.C.
登録日2005-11-14
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
Structure, 13, 2005
1TZC
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Crystal structure of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum in complex with 5-phosphoarabinonate
分子名称: 5-PHOSPHOARABINONIC ACID, GLYCEROL, SULFATE ION, ...
著者Swan, M.K, Hansen, T, Schoenheit, P, Davies, C.
登録日2004-07-09
公開日2004-07-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A novel phosphoglucose/phosphomannose isomease from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16 A resolution
J.Biol.Chem., 279, 2004
1TZB
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Crystal structure of native phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum
分子名称: GLYCEROL, SULFATE ION, glucose-6-phosphate isomerase, ...
著者Swan, M.K, Hansen, T, Schoenheit, P, Davies, C.
登録日2004-07-09
公開日2004-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献A novel phosphoglucose/phosphomannose isomease from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16 A resolution
J.Biol.Chem., 279, 2004
2O2R
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Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2Q
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Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADP
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, MAGNESIUM ION, ...
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2P
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Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase
分子名称: Formyltetrahydrofolate dehydrogenase, GLYCEROL, SULFATE ION
著者Tsybovsky, Y, Donato, H, Krupenko, N.I, Davies, C, Krupenko, S.A.
登録日2006-11-30
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
7UVF
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Crystal structure of ZED8 Fab complex with CD8 alpha
分子名称: CHLORIDE ION, GLYCEROL, Immunoglobulin heavy chain, ...
著者Yu, C, Davies, C, Koerber, J.T, Williams, S.
登録日2022-05-01
公開日2022-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Preclinical development of ZED8, an 89 Zr immuno-PET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy.
Eur J Nucl Med Mol Imaging, 50, 2023
5KSH
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Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing an A501T mutation associated with cephalosporin resistance
分子名称: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
著者Fedarovich, A, Davies, C.
登録日2016-07-08
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.
Biochemistry, 56, 2017
1QX4
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Structrue of S127P mutant of cytochrome b5 reductase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase
著者Bewley, M.C, Davis, C.A, Marohnic, C.C, Taormina, D, Barber, M.J.
登録日2003-09-04
公開日2004-09-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site
Biochemistry, 42, 2003
1S3I
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Crystal structure of the N terminal hydrolase domain of 10-formyltetrahydrofolate dehydrogenase
分子名称: 10-formyltetrahydrofolate dehydrogenase, BETA-MERCAPTOETHANOL
著者Chumanevich, A.A, Krupenko, S.A, Davies, C.
登録日2004-01-13
公開日2004-01-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain.
J.Biol.Chem., 279, 2004
1NJ4
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Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 1.9 A resolution
分子名称: Penicillin-binding protein 5
著者Nicola, G, Nicholas, R.A, Davies, C.
登録日2002-12-30
公開日2003-01-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
3BEC
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Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic cephalosporin
分子名称: (2R)-2-[(R)-{[(6S)-6-amino-6-carboxyhexanoyl]amino}(carboxy)methyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 5
著者Powell, A.J, Davies, C.
登録日2007-11-16
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle
J.Mol.Biol., 381, 2008
3MZF
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Structure of penicillin-binding protein 5 from E. coli: imipenem acyl-enzyme complex
分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
著者Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
登録日2010-05-12
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
3MZD
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Structure of penicillin-binding protein 5 from E. coli: cloxacillin acyl-enzyme complex
分子名称: (2R,4S)-2-[(1S)-1-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolid ine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
著者Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
登録日2010-05-12
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
3MZE
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Structure of penicillin-binding protein 5 from E.coli: cefoxitin acyl-enzyme complex
分子名称: (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
著者Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
登録日2010-05-12
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
3BEB
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Crystal structure of E. coli penicillin-binding protein 5 in complex with a peptide-mimetic penicillin
分子名称: (2R,4S)-2-[(1R)-1-{[(6S)-6-amino-6-carboxyhexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 5
著者Heilemann, J, Powell, A.J, Davies, C.
登録日2007-11-16
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of complexes of bacterial DD-peptidases with peptidoglycan-mimetic ligands: the substrate specificity puzzle
J.Mol.Biol., 381, 2008
2MGX
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NMR structure of SRA1p C-terminal domain
分子名称: Steroid receptor RNA activator 1
著者Bilinovich, S.M, Davis, C.M, Morris, D.L, Ray, L.A, Prokop, J.W, Buchan, G.J, Leeper, T.C.
登録日2013-11-10
公開日2014-02-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The C-Terminal Domain of SRA1p Has a Fold More Similar to PRP18 than to an RRM and Does Not Directly Bind to the SRA1 RNA STR7 Region.
J.Mol.Biol., 426, 2014

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