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PDB: 174 件

4KI2
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Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA
分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2013-05-01
公開日2013-09-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes.
Acta Crystallogr.,Sect.F, 69, 2013
8SQ9
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SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, MAGNESIUM ION, Non-structural protein 7, ...
著者Small, G.I, Darst, S.A, Campbell, E.A.
登録日2023-05-04
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
8SQJ
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SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode
分子名称: 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ...
著者Small, G.I, Darst, S.A, Campbell, E.A.
登録日2023-05-04
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
8SQK
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SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate
分子名称: 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ...
著者Small, G.I, Darst, S.A, Campbell, E.A.
登録日2023-05-04
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
4LJZ
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Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5871 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LK1
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Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8369 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LK0
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Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex
分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9103 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LLG
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Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex
分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2013-07-09
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.7936 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L3I
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Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)
分子名称: Protein regulator of cytokinesis 1
著者Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M.
登録日2013-06-06
公開日2013-07-17
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (3.6005 Å)
主引用文献Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
4L5G
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Crystal structure of Thermus thermophilus CarD
分子名称: CarD
著者Srivastava, D.B, Westblade, L.F, Campbell, E.A, Darst, S.A.
登録日2013-06-11
公開日2013-07-31
最終更新日2013-08-21
実験手法X-RAY DIFFRACTION (2.3902 Å)
主引用文献Structure and function of CarD, an essential mycobacterial transcription factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L6Y
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Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)
分子名称: Protein regulator of cytokinesis 1
著者Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M.
登録日2013-06-13
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3015 Å)
主引用文献Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
1SC5
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Sigma-28(FliA)/FlgM complex
分子名称: RNA polymerase sigma factor FliA, anti-sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2004-02-11
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation.
Mol.Cell, 14, 2004
3NRX
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Insights into anti-parallel microtubule crosslinking by PRC1, a conserved non-motor microtubule binding protein
分子名称: Protein regulator of cytokinesis 1
著者Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A.
登録日2010-06-30
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
1RIO
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Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ...
著者Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A.
登録日2003-11-17
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a ternary transcription activation complex.
Mol.Cell, 13, 2004
3NRY
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Insights into anti-parallel microtubule crosslinking by PRC1, a conserved microtubule binding protein
分子名称: Protein regulator of cytokinesis 1
著者Kapoor, T.M, Subramanian, R, Wilson-Kubalek, E.M, Arthur, C.P, Bick, M.J, Campbell, E.A, Darst, S.A, Milligan, R.A.
登録日2010-07-01
公開日2010-08-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.
Cell(Cambridge,Mass.), 142, 2010
3MGC
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BU of 3mgc by Molmil
Teg12 Apo
分子名称: GLYCEROL, IMIDAZOLE, N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER, ...
著者Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F.
登録日2010-04-05
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone.
Biochemistry, 49, 2010
3MG9
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Teg 12 Binary Structure Complexed with the Teicoplanin Aglycone
分子名称: FORMIC ACID, GLYCEROL, TEG12, ...
著者Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F.
登録日2010-04-05
公開日2010-06-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone.
Biochemistry, 49, 2010
1TH8
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Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II
分子名称: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
著者Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigian, J, Leon, F, Darst, S.A, Campbell, E.A.
登録日2004-06-01
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1RP3
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Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM
分子名称: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2003-12-02
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation
Mol.Cell, 14, 2004
3NIB
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Teg14 Apo
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Teg14
著者Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F.
登録日2010-06-15
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A resolution structure of the glycopeptide sulfotransferase Teg14
Acta Crystallogr.,Sect.D, 66, 2010
3MGB
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Teg 12 Ternary Structure Complexed with PAP and the Teicoplanin Aglycone
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, ACETATE ION, CHLORIDE ION, ...
著者Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F.
登録日2010-04-05
公開日2010-06-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone.
Biochemistry, 49, 2010
1TIL
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BU of 1til by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA:Poised for phosphorylation complex with ATP, crystal form II
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
著者Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
登録日2004-06-02
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1THN
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BU of 1thn by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
著者Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
登録日2004-06-01
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
1TID
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BU of 1tid by Molmil
Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ...
著者Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A.
登録日2004-06-02
公開日2004-06-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA.
J.Mol.Biol., 340, 2004
6OMF
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CryoEM structure of SigmaS-transcription initiation complex with activator Crl
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A.
登録日2019-04-18
公開日2019-08-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase.
Proc.Natl.Acad.Sci.USA, 116, 2019

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件を2024-08-21に公開中

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