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PDB: 174 件
6OMF
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BU of 6omf by Molmil
CryoEM structure of SigmaS-transcription initiation complex with activator Crl
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A.
登録日2019-04-18
公開日2019-08-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase.
Proc.Natl.Acad.Sci.USA, 116, 2019
4X8K
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BU of 4x8k by Molmil
Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2
分子名称: 1,2-ETHANEDIOL, RNA polymerase sigma factor SigA, RNA polymerase-binding protein RbpA, ...
著者Hubin, E.A, Flack, J.E, Tabib-Salazar, A, Paget, M.S, Darst, S.A, Campbell, E.A.
登録日2014-12-10
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XLS
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BU of 4xls by Molmil
Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter.
分子名称: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4XLR
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BU of 4xlr by Molmil
Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA
分子名称: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4XLN
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BU of 4xln by Molmil
Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA
分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XAX
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BU of 4xax by Molmil
Crystal structure of Thermus thermophilus CarD in complex with the Thermus aquaticus RNA polymerase beta1 domain
分子名称: 1,2-ETHANEDIOL, CarD, DNA-directed RNA polymerase subunit beta domain 1
著者Chen, J, Bae, B, Campbell, E.A, Darst, S.A.
登録日2014-12-15
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4XLQ
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BU of 4xlq by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter
分子名称: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XSZ
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BU of 4xsz by Molmil
Crystal structure of CBR 9393 bound to Escherichia coli RNA polymerase holoenzyme
分子名称: 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(piperazin-1-yl)ethyl]-2-(trifluoromethyl)aniline, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2015-01-22
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.683 Å)
主引用文献CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XSX
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BU of 4xsx by Molmil
Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2015-01-22
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.708 Å)
主引用文献CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XLP
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BU of 4xlp by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter
分子名称: DNA (25-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XSY
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BU of 4xsy by Molmil
Crystal structure of CBR 9379 bound to Escherichia coli RNA polymerase holoenzyme
分子名称: 3-{[(2,6-dichlorophenyl)carbamoyl]amino}-N-hydroxy-N'-phenyl-5-(trifluoromethyl)benzenecarboximidamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2015-01-22
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.007 Å)
主引用文献CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
3TBI
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BU of 3tbi by Molmil
Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain
分子名称: DNA-directed RNA polymerase subunit beta, RNA polymerase-associated protein Gp33
著者Twist, K.A.F, Campbell, E.A, Darst, S.A.
登録日2011-08-06
公開日2011-11-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of T4 gp33 bound to E. coli RNAP beta-flap domain
To be Published
3UGO
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BU of 3ugo by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT)
分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
3UGP
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BU of 3ugp by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT)
分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
1YNJ
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BU of 1ynj by Molmil
Taq RNA polymerase-Sorangicin complex
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
登録日2005-01-24
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1ZPQ
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BU of 1zpq by Molmil
STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein
分子名称: Regulatory protein CII
著者Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Joachimiak, A, Darst, S.A, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-17
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
1ZS4
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BU of 1zs4 by Molmil
Structure of bacteriophage lambda cII protein in complex with DNA
分子名称: DNA - 27mer, Regulatory protein CII
著者Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A.
登録日2005-05-23
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
8E8M
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BU of 8e8m by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-25
公開日2023-03-22
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E74
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BU of 8e74 by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-23
公開日2023-03-22
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E82
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BU of 8e82 by Molmil
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-25
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E79
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BU of 8e79 by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor
分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-23
公開日2023-03-22
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E95
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BU of 8e95 by Molmil
Mycobacterium tuberculosis RNAP elongation complex
分子名称: DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Delbeau, M, Darst, S.A, Campbell, E.A.
登録日2022-08-26
公開日2023-03-22
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
1SIG
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BU of 1sig by Molmil
CRYSTAL STRUCTURE OF A SIGMA70 SUBUNIT FRAGMENT FROM ESCHERICHIA COLI RNA POLYMERASE
分子名称: RNA POLYMERASE PRIMARY SIGMA FACTOR
著者Malhotra, A, Severinova, E, Darst, S.A.
登録日1997-02-18
公開日1997-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase.
Cell(Cambridge,Mass.), 87, 1996
2GHO
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BU of 2gho by Molmil
Recombinant Thermus aquaticus RNA polymerase for Structural Studies
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta',DNA-directed RNA polymerase subunit beta'
著者Lamour, V, Darst, S.A.
登録日2006-03-27
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Recombinant Thermus aquaticus RNA Polymerase for Structural Studies.
J.Mol.Biol., 359, 2006
2ETN
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BU of 2etn by Molmil
Crystal structure of Thermus aquaticus Gfh1
分子名称: anti-cleavage anti-GreA transcription factor Gfh1
著者Lamour, V, Hogan, B.P, Erie, D.A, Darst, S.A.
登録日2005-10-27
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage.
J.Mol.Biol., 356, 2006

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