5TC1
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![BU of 5tc1 by Molmil](/molmil-images/mine/5tc1) | In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2 | 分子名称: | Capsid protein, Maturation protein, phage MS2 genome | 著者 | Dai, X.H, Li, Z.H, Lai, M, Shu, S, Du, Y.S, Zhou, Z.H, Sun, R. | 登録日 | 2016-09-13 | 公開日 | 2016-12-07 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. Nature, 541, 2017
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6B43
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![BU of 6b43 by Molmil](/molmil-images/mine/6b43) | CryoEM structure and atomic model of the Kaposi's sarcoma-associated herpesvirus capsid | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Dai, X.H, Gong, D.Y, Sun, R, Zhou, Z.H. | 登録日 | 2017-09-25 | 公開日 | 2017-11-08 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication. Nature, 553, 2018
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6CGR
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6B1T
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![BU of 6b1t by Molmil](/molmil-images/mine/6b1t) | Improved cryoEM structure of human adenovirus type 5 with atomic details of minor proteins VI and VII | 分子名称: | Hexon protein, Hexon-interlacing protein, Penton protein, ... | 著者 | Dai, X.H, Wu, L, Sun, R, Zhou, Z.H. | 登録日 | 2017-09-18 | 公開日 | 2017-09-27 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Atomic Structures of Minor Proteins VI and VII in Human Adenovirus. J. Virol., 91, 2017
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2EXX
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![BU of 2exx by Molmil](/molmil-images/mine/2exx) | Crystal structure of HSCARG from Homo sapiens in complex with NADP | 分子名称: | GLYCEROL, HSCARG protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Dai, X, Chen, Q, Yao, D, Liang, Y, Dong, Y, Gu, X, Zheng, X, Luo, M. | 登録日 | 2005-11-09 | 公開日 | 2006-11-21 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. Proc.Natl.Acad.Sci.USA, 104, 2007
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7QAJ
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![BU of 7qaj by Molmil](/molmil-images/mine/7qaj) | ZK002 with Anti-angiogenic and Anti-inflamamtory Properties | 分子名称: | SULFATE ION, Snaclec clone 2100755 alpha, Snaclec clone 2100755 beta | 著者 | Wong, W.Y, Chan, B.D, Muk Lan Lee, M, Dai, X, Tsim, K.W.K, Hsiao, W.L.W, Li, M, Li, X.Y, Tai, W.C.S. | 登録日 | 2021-11-17 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties. Front Pharmacol, 14, 2023
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8SZA
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8SZB
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6OD7
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![BU of 6od7 by Molmil](/molmil-images/mine/6od7) | Herpes simplex virus type 1 (HSV-1) pUL6 portal protein, dodecameric complex | 分子名称: | Portal protein | 著者 | Liu, Y.T, Jih, J, Dai, X.H, Bi, G.Q, Zhou, Z.H. | 登録日 | 2019-03-26 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. Nature, 570, 2019
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6W19
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![BU of 6w19 by Molmil](/molmil-images/mine/6w19) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-03 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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6W2D
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![BU of 6w2d by Molmil](/molmil-images/mine/6w2d) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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6W2E
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![BU of 6w2e by Molmil](/molmil-images/mine/6w2e) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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5U6I
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![BU of 5u6i by Molmil](/molmil-images/mine/5u6i) | Discovery of MLi-2, an Orally Available and Selective LRRK2 Inhibitor that Reduces Brain Kinase Activity | 分子名称: | 3-[2-(morpholin-4-yl)pyridin-4-yl]-5-[(propan-2-yl)oxy]-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Scott, J.D, DeMong, D.E, Fell, M.J, Mirescu, C, Basu, K, Greshock, T.J, Morrow, J.A, Xiao, L, Hruza, A, Harris, J, Tiscia, H.E, Chang, R.K, Embrey, M.W, McCauley, J.A, Li, W, Lin, S, Liu, H, Dai, X, Baptista, M, Agnihotri, G, Columbus, J, Mei, H, Poirier, M, Zhou, X, Lin, Y, Yin, Z, Sanders, J.M, Drolet, R.E, Kern, J.T, Kennedy, M.E, Parker, E.M, Stamford, A.W, Nargund, R, Miller, M.W. | 登録日 | 2016-12-08 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity. J. Med. Chem., 60, 2017
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6ODM
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![BU of 6odm by Molmil](/molmil-images/mine/6odm) | Herpes simplex virus type 1 (HSV-1) portal vertex-adjacent capsid/CATC, asymmetric unit | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, Y.T, Jih, J, Dai, X.H, Bi, G.Q, Zhou, Z.H. | 登録日 | 2019-03-26 | 公開日 | 2019-06-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. Nature, 570, 2019
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3E5M
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![BU of 3e5m by Molmil](/molmil-images/mine/3e5m) | Crystal structure of the HSCARG Y81A mutant | 分子名称: | NmrA-like family domain-containing protein 1 | 著者 | Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X. | 登録日 | 2008-08-14 | 公開日 | 2009-05-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | NADPH is an allosteric regulator of HSCARG J.Mol.Biol., 387, 2009
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6PPB
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![BU of 6ppb by Molmil](/molmil-images/mine/6ppb) | Kaposi's sarcoma-associated herpesvirus (KSHV), C5 portal vertex structure | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2019-07-06 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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6PPH
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![BU of 6pph by Molmil](/molmil-images/mine/6pph) | Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-binding structure | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2019-07-06 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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3DXF
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![BU of 3dxf by Molmil](/molmil-images/mine/3dxf) | Crystal structure of the HSCARG R37A mutant | 分子名称: | NmrA-like family domain-containing protein 1 | 著者 | Li, Y, Meng, G, Dai, X, Luo, M, Zheng, X. | 登録日 | 2008-07-24 | 公開日 | 2009-05-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | NADPH is an allosteric regulator of HSCARG J.Mol.Biol., 387, 2009
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6PPD
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![BU of 6ppd by Molmil](/molmil-images/mine/6ppd) | Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-absent structure | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2019-07-06 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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6NHJ
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![BU of 6nhj by Molmil](/molmil-images/mine/6nhj) | Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development | 分子名称: | Major capsid protein, Minor capsid protein, Small capsomere-interacting protein, ... | 著者 | Liu, W, Dai, X.H, Jih, J, Chan, K, Trang, P, Yu, X.K, Balogun, R, Mei, Y, Liu, F.Y, Zhou, Z.H. | 登録日 | 2018-12-22 | 公開日 | 2019-03-06 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. PLoS Pathog., 15, 2019
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6PPI
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![BU of 6ppi by Molmil](/molmil-images/mine/6ppi) | Kaposi's sarcoma-associated herpesvirus (KSHV), C12 portal dodecamer structure | 分子名称: | Portal protein | 著者 | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2019-07-07 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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3J32
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![BU of 3j32 by Molmil](/molmil-images/mine/3j32) | An asymmetric unit map from electron cryo-microscopy of Haliotis diversicolor molluscan hemocyanin isoform 1 (HdH1) | 分子名称: | Hemocyanin isoform 1 | 著者 | Zhang, Q, Dai, X, Cong, Y, Zhang, J, Chen, D.-H, Dougherty, M, Wang, J, Ludtke, S, Schmid, M.F, Chiu, W. | 登録日 | 2013-02-20 | 公開日 | 2013-04-17 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism. Structure, 21, 2013
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8CXH
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![BU of 8cxh by Molmil](/molmil-images/mine/8cxh) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | Ankyrin repeat family A protein 2,Envelope E protein, C10 heavy chain, C10 light chain, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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8CXI
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![BU of 8cxi by Molmil](/molmil-images/mine/8cxi) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | A11 heavy chain, A11 light chain, Ankyrin repeat family A protein 2,Envelope E protein, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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8CXG
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![BU of 8cxg by Molmil](/molmil-images/mine/8cxg) | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy | 分子名称: | Ankyrin repeat family A protein 2,Envelope E protein, C8 scFv heavy chain, C8 scFv light chain, ... | 著者 | Liu, W, Zhang, X.K, Gong, D.Y, Dai, X.H, Sharma, A, Zhang, T.H, Rey, F, Zhou, Z.H. | 登録日 | 2022-05-21 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy To Be Published
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