5MDH
| CRYSTAL STRUCTURE OF TERNARY COMPLEX OF PORCINE CYTOPLASMIC MALATE DEHYDROGENASE ALPHA-KETOMALONATE AND TNAD AT 2.4 ANGSTROMS RESOLUTION | 分子名称: | ALPHA-KETOMALONIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Chapman, A.D.M, Cortes, A, Dafforn, T.R, Clarke, A.R, Brady, R.L. | 登録日 | 1998-10-08 | 公開日 | 1999-05-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of substrate specificity in malate dehydrogenases: crystal structure of a ternary complex of porcine cytoplasmic malate dehydrogenase, alpha-ketomalonate and tetrahydoNAD. J.Mol.Biol., 285, 1999
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3D25
| Crystal structure of HA-1 minor histocompatibility antigen bound to human class I MHC HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Nicholls, S, Piper, K.P, Mohammed, F, Dafforn, T.R, Tenzer, S, Salim, M, Mahendra, P, Craddock, C, van Endert, P, Schild, H, Cobbold, M, Engelhard, V.H, Moss, P.A.H, Willcox, B.E. | 登録日 | 2008-05-07 | 公開日 | 2009-02-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition Proc.Natl.Acad.Sci.USA, 106, 2009
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1Y2O
| Structure of N-terminal domain IRSp53/BAIAP2 | 分子名称: | BAI1-associated protein 2 isoform 1 | 著者 | Millard, T.H, Bompard, G, Heung, M.-Y, Dafforn, T.R, Scott, D.J, Machesky, L.M, Futterer, K. | 登録日 | 2004-11-23 | 公開日 | 2005-02-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53 Embo J., 24, 2005
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1QLP
| 2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS | 分子名称: | ALPHA-1-ANTITRYPSIN | 著者 | Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A. | 登録日 | 1999-09-10 | 公開日 | 1999-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci., 9, 2000
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8P30
| Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P31
| Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2X
| Structure of human SIT1:ACE2 complex (open PD conformation) | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2Y
| Structure of human SIT1:ACE2 complex (closed PD conformation) | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2W
| Structure of human SIT1 (focussed map / refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3 | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2Z
| Structure of human SIT1 bound to L-pipecolate (focussed map / refinement) | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | 登録日 | 2023-05-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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