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PDB: 1609 件

2O3Z
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X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate
分子名称: 3-(heptyloxy)benzoic acid, CHLORIDE ION, SULFATE ION, ...
著者Gennadios, H.A, Whittington, D.A, Christianson, D.W.
登録日2006-12-02
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC.
Bioorg.Med.Chem., 15, 2007
2IMP
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Crystal structure of lactaldehyde dehydrogenase from E. coli: the ternary complex with lactate (occupancy 0.5) and NADH. Crystals soaked with (L)-Lactate.
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, LACTIC ACID, Lactaldehyde dehydrogenase, ...
著者Di Costanzo, L, Gomez, G.A, Christianson, D.W.
登録日2006-10-04
公開日2007-02-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Lactaldehyde Dehydrogenase from Escherichia coli and Inferences Regarding Substrate and Cofactor Specificity.
J.Mol.Biol., 366, 2007
2GC3
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The crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with mannose 6-phosphate and zinc
分子名称: 6-O-phosphono-alpha-D-mannopyranose, Glucose-6-phosphate isomerase, ZINC ION
著者Berrisford, J.M, Rice, D.W, Baker, P.J.
登録日2006-03-13
公開日2006-04-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Evidence Supporting a cis-enediol-based Mechanism for Pyrococcus furiosus Phosphoglucose Isomerase
J.Mol.Biol., 358, 2006
2O36
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Crystal structure of engineered thimet oligopeptidase with neurolysin specificity in neurotensin cleavage site
分子名称: Thimet oligopeptidase, ZINC ION
著者Rodgers, D.W, Lim, E.J.
登録日2006-11-30
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase.
J.Biol.Chem., 282, 2007
2OA6
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Aristolochene synthase from Aspergillus terreus complexed with pyrophosphate
分子名称: Aristolochene synthase, BETA-MERCAPTOETHANOL, GLYCEROL, ...
著者Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W.
登録日2006-12-15
公開日2007-01-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate
Biochemistry, 46, 2007
2IDR
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Crystal structure of translation initiation factor EIF4E from wheat
分子名称: Eukaryotic translation initiation factor 4E-1
著者Monzingo, A.F, Sadow, J, Dhaliwal, S, Lyon, A, Hoffman, D.W, Robertus, J.D, Browning, K.S.
登録日2006-09-15
公開日2007-06-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
2IJD
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Crystal Structure of the Poliovirus Precursor Protein 3CD
分子名称: Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ...
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2006-09-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
2ILU
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Crystal structure of lactaldehyde dehydrogenase from E. coli: the binary complex with NADPH
分子名称: Aldehyde dehydrogenase A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Di Costanzo, L, Gomez, G, Christianson, D.W.
登録日2006-10-03
公開日2007-05-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.
J.Mol.Biol., 366, 2007
2O2S
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The structure of T. gondii enoyl acyl carrier protein reductase in complex with NAD and triclosan
分子名称: Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
著者Muench, S.P, Prigge, S.T, McLeod, R, Rafferty, J.B, Kirisits, M.J, Roberts, C.W, Mui, E.J, Rice, D.W.
登録日2006-11-30
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2J7Z
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Crystal Structure of recombinant Human Stromal Cell-Derived Factor- 1alpha
分子名称: STROMAL CELL-DERIVED FACTOR 1 ALPHA
著者Ryu, E.K, Kim, T.G, Kwon, T.H, Jung, I.D, Ryu, D.W, Park, Y.-M, Ahn, K, Ban, C.
登録日2006-10-18
公開日2006-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Recombinant Human Stromal Cell-Derived Factor-1Alpha.
Proteins, 67, 2007
2IDV
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Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1
著者Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S.
登録日2006-09-15
公開日2007-06-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
2IER
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Crystal Structure of Aquifex aeolicus LpxC Complexed with Uridine 5'-Diphosphate
分子名称: GLYCEROL, PALMITIC ACID, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ...
著者Gennadios, H.A, Christianson, D.W.
登録日2006-09-19
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
Biochemistry, 45, 2006
2OJP
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The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y
分子名称: Dihydrodipicolinate synthase, GLYCEROL
著者Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A.
登録日2007-01-13
公開日2008-01-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
2O3E
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Crystal structure of engineered neurolysin with thimet oligopeptidase specificity for neurotensin cleavage site.
分子名称: Neurolysin, ZINC ION
著者Rodgers, D.W, Lim, E.J.
登録日2006-12-01
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase.
J.Biol.Chem., 282, 2007
2O50
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The crystal structure of Toxoplasma gondii Enoyl acyl carrier protein reductase
分子名称: Enoyl-acyl carrier reductase
著者Muench, S.P, Prigge, S.T, McLeod, R, Rafferty, J.B, Rice, D.W.
登録日2006-12-05
公開日2006-12-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2ODM
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Crystal structure of S. aureus YlaN, an essential leucine rich protein involved in the control of cell shape
分子名称: UPF0358 protein MW0995
著者Xu, L, Sedelnikova, S.E, Baker, P.J, Errington, J, Hunt, A, Rice, D.W.
登録日2006-12-23
公開日2007-06-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal structure of S. aureus YlaN, an essential leucine rich protein involved in the control of cell shape.
Proteins, 68, 2007
2OMV
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Crystal structure of InlA S192N Y369S/hEC1 complex
分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ...
著者Wollert, T, Heinz, D.W, Schubert, W.D.
登録日2007-01-23
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Extending the host range of Listeria monocytogenes by rational protein design.
Cell(Cambridge,Mass.), 129, 2007
3KB9
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Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation
分子名称: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ...
著者Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W.
登録日2009-10-20
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
4Q42
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Crystal structure of Schistosoma mansoni arginase in complex with L-ornithine
分子名称: Arginase, GLYCEROL, L-ornithine, ...
著者Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W.
登録日2014-04-12
公開日2014-07-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
Biochemistry, 53, 2014
4QA4
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Crystal structure of H334R HDAC8 in complex with M344
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
1YXD
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Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A
分子名称: CHLORIDE ION, LYSINE, POTASSIUM ION, ...
著者Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A.
登録日2005-02-20
公開日2005-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
Acta Crystallogr.,Sect.D, 61, 2005
4QNJ
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The structure of wt A. thaliana IGPD2 in complex with Mn2+ and formate at 1.3A resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FORMIC ACID, ...
著者Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R, Hawkes, T.R, Baker, P.J, Rice, D.W.
登録日2014-06-18
公開日2015-06-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
Structure, 23, 2015
4QA0
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Crystal structure of C153F HDAC8 in complex with SAHA
分子名称: GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.242 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
4QA3
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Crystal structure of T311M HDAC8 in complex with Trichostatin A (TSA)
分子名称: GLYCEROL, Histone deacetylase 8, POTASSIUM ION, ...
著者Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2014-05-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.876 Å)
主引用文献Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders.
Acs Chem.Biol., 9, 2014
4MHL
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The crystal structure of human interleukin-11
分子名称: FORMAMIDE, Interleukin-11, SULFATE ION
著者Griffin, M.D.W.
登録日2013-08-29
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6.
Acta Crystallogr.,Sect.D, 70, 2014

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件を2024-11-06に公開中

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