4MHL
The crystal structure of human interleukin-11
Summary for 4MHL
| Entry DOI | 10.2210/pdb4mhl/pdb |
| Descriptor | Interleukin-11, SULFATE ION, FORMAMIDE, ... (4 entities in total) |
| Functional Keywords | four-helix bundle, long-chain helical cytokine, cytokine, growth factor, interleukin-11 receptor subunit alpha, membrane glycoprotein 130, secreted, protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P20809 |
| Total number of polymer chains | 1 |
| Total formula weight | 19393.52 |
| Authors | Griffin, M.D.W. (deposition date: 2013-08-29, release date: 2014-09-03, Last modification date: 2023-09-20) |
| Primary citation | Putoczki, T.L.,Dobson, R.C.,Griffin, M.D. The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6. Acta Crystallogr.,Sect.D, 70:2277-2285, 2014 Cited by PubMed: 25195742DOI: 10.1107/S1399004714012267 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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