2O2S

The structure of T. gondii enoyl acyl carrier protein reductase in complex with NAD and triclosan

Summary for 2O2S

Entry DOI	10.2210/pdb2o2s/pdb
Related	1D7O 1D8A 1JVF 1NHG 2O2Y 2O50
Descriptor	Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total)
Functional Keywords	enoyl reductase, triclosan, rossmann fold, oxidoreductase
Biological source	Toxoplasma gondii
Total number of polymer chains	2
Total formula weight	68689.04
Authors	Muench, S.P.,Prigge, S.T.,McLeod, R.,Rafferty, J.B.,Kirisits, M.J.,Roberts, C.W.,Mui, E.J.,Rice, D.W. (deposition date: 2006-11-30, release date: 2006-12-26, Last modification date: 2023-10-25)
Primary citation	Muench, S.P.,Prigge, S.T.,McLeod, R.,Rafferty, J.B.,Kirisits, M.J.,Roberts, C.W.,Mui, E.J.,Rice, D.W. Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents ACTA CRYSTALLOGR.,SECT.D, 63:328-338, 2007 Cited by PubMed: 17327670 DOI: 10.1107/S0907444906053625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation