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PDB: 1951 件

7OYL
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Phosphoglucose isomerase of Aspergillus fumigatus in complexed with Glucose-6-phosphate
分子名称: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Raimi, O.G, Yan, K, Fang, W, van Aalten, D.M.F.
登録日2021-06-24
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis.
Mbio, 13, 2022
7P5O
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Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase
著者Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
To Be Published
6YL5
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BU of 6yl5 by Molmil
Crystal structure of the SAM-SAH riboswitch with SAH
分子名称: Chains: A,B,C,D,E,F,G,H,I,J,K,L, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-06
公開日2020-07-22
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 2020
6YMI
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Crystal structure of the SAM-SAH riboswitch with AMP.
分子名称: 5-BROMOCYTIDINE 5'-(DIHYDROGEN PHOSPHATE), ADENOSINE MONOPHOSPHATE, Chains: A,C,F,I,M,O, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-08
公開日2020-07-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 48, 2020
6YMJ
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Crystal structure of the SAM-SAH riboswitch with adenosine.
分子名称: 5-BROMOCYTIDINE 5'-(DIHYDROGEN PHOSPHATE), ADENOSINE, Chains: A,C,F,I,M,O, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-08
公開日2020-07-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 48, 2020
7PIZ
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The structure of phosphoglucomutase from Candida albicans
分子名称: Phosphoglucomutase, SULFATE ION
著者Yan, K, van Aalten, D.M.F.
登録日2021-08-23
公開日2022-09-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
To Be Published
6YLB
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BU of 6ylb by Molmil
Crystal structure of the SAM-SAH riboswitch with SAM
分子名称: Chains: A,C,F,I,M,O, Chains: B,D,G,J,N,P, S-ADENOSYLMETHIONINE
著者Huang, L, Lilley, D.M.J.
登録日2020-04-07
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 2020
6YML
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BU of 6yml by Molmil
Crystal structure of the SAM-SAH riboswitch with decarboxylated SAH
分子名称: 5'-S-(3-aminopropyl)-5'-thioadenosine, ADENOSINE MONOPHOSPHATE, Chains: A,C, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-08
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 48, 2020
7PJC
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The structure of Candida albicans phosphoglucomutase with isothiazolone modification on Cys359
分子名称: GLYCEROL, Phosphoglucomutase, SULFATE ION, ...
著者Yan, K, van Aalten, D.M.F.
登録日2021-08-23
公開日2022-09-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
To Be Published
7PPR
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BU of 7ppr by Molmil
The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus
分子名称: CHLORIDE ION, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase
著者Morton, S, Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-09-14
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Genetic and structural validation of UDP-glucose pyrophosphorylase as a novel antifungal target against Aspergillus fumigatus
To Be Published
6YMK
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Crystal structure of the SAM-SAH riboswitch with AMP
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Chains: A,C,F,I,M,O, Chains: B,D,G,J,N,P, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-08
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 48, 2020
6YMM
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Crystal structure of the SAM-SAH riboswitch with SAM from space group P312
分子名称: Chains: A, Chains: B,D, S-ADENOSYLMETHIONINE, ...
著者Huang, L, Lilley, D.M.J.
登録日2020-04-08
公開日2020-07-22
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and ligand-induced folding of the SAM/SAH riboswitch.
Nucleic Acids Res., 48, 2020
4OJI
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BU of 4oji by Molmil
Crystal Structure of Twister Ribozyme
分子名称: MAGNESIUM ION, RNA (52-MER)
著者Liu, Y, Wilson, T.J, McPhee, S.A, Lilley, D.M.J.
登録日2014-01-21
公開日2014-07-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and mechanistic investigation of the twister ribozyme.
Nat.Chem.Biol., 10, 2014
6BZ5
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Structure and mechanism of salicylate hydroxylase from Pseudomonas putida G7
分子名称: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ...
著者Nagem, R.A.P, Costa, D.M.A.
登録日2017-12-22
公開日2018-12-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Catalytic mechanism for the conversion of salicylate into catechol by the flavin-dependent monooxygenase salicylate hydroxylase.
Int.J.Biol.Macromol., 129, 2019
6VWB
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BU of 6vwb by Molmil
Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81
分子名称: Crossover junction endonuclease MUS81
著者Payliss, B, Houliston, S, Lemak, A, Arrowsmith, C.H, Wyatt, H.D.M.
登録日2020-02-19
公開日2021-02-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease
Cell Rep, 41, 2022
5LRV
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BU of 5lrv by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, PHOSPHATE ION, ...
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LQT
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BU of 5lqt by Molmil
RNA duplex has central consecutive GA pairs flanked by G-C basepairs
分子名称: CALCIUM ION, MAGNESIUM ION, RNA (5'-R(*GP*(CBV)P*CP*GP*GP*(6MZ)P*CP*GP*GP*C)-3'), ...
著者Huang, L, Lilley, D.M.J.
登録日2016-08-17
公開日2017-06-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Control of box C/D snoRNP assembly by N(6)-methylation of adenine.
EMBO Rep., 18, 2017
4EZA
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BU of 4eza by Molmil
Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2
分子名称: Ras GTPase-activating-like protein IQGAP2
著者Van Aalten, D.M.F, Dixon, M.J, Gray, A, Schenning, M, Agacan, M, Leslie, N.R, Downes, C.P, Batty, I.H, Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2012-05-02
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.
J.Biol.Chem., 287, 2012
1H0G
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BU of 1h0g by Molmil
Complex of a chitinase with the natural product cyclopentapeptide argadin from Clonostachys
分子名称: Argadin, CHITINASE B, GLYCEROL
著者Houston, D, Shiomi, K, Arai, N, Omura, S, Peter, M.G, Turberg, A, Synstad, B, Eijsink, V.G.H, Aalten, D.M.F.
登録日2002-06-19
公開日2002-06-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High Resolution Inhibited Complexes of a Chitinase with Natural Product Cyclopentapeptides - Peptide Mimicry of a Carbohydrate Substrate
Proc.Natl.Acad.Sci.USA, 99, 2002
1GUV
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BU of 1guv by Molmil
Structure of human chitotriosidase
分子名称: 1,2-ETHANEDIOL, CHITOTRIOSIDASE
著者Von Moeller, H, Houston, D, Boot, R.G, Aerts, J.M.F.G, Van Aalten, D.M.F.
登録日2002-01-31
公開日2003-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of Human Chitotriosidase - Implications for Specific Inhibitor Design and Function of Mammalian Chitinase-Like Lectins
J.Biol.Chem., 277, 2002
6IAR
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BU of 6iar by Molmil
Tricyclic indazoles a novel class of selective estrogen receptor degrader antagonists
分子名称: 3-[4-[(6~{R})-7-(2-methylpropyl)-3,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]phenyl]propanoic acid, Estrogen receptor
著者Scott, J.S, Bailey, A, Buttar, D, Carbajo, R.J, Curwen, J, Davies, R.D.M, Degorce, S.L, Donald, C, Gangl, E, Greenwood, R, Groombridge, S.D, Johnson, T, Lamont, S, Lawson, M, Lister, A, Morrow, C, Moss, T, Pink, J.H, Polanski, R.
登録日2018-11-27
公開日2019-01-23
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.
J.Med.Chem., 62, 2019
1GSW
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BU of 1gsw by Molmil
CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
著者Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
登録日2002-01-09
公開日2002-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSX
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
著者Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L.
登録日2002-01-09
公開日2002-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GOI
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Crystal structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 A resolution
分子名称: CHITINASE B, GLYCEROL, SULFATE ION
著者Kolstad, G, Synstad, B, Eijsink, V.G.H, Van Aalten, D.M.F.
登録日2001-10-21
公開日2001-11-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of the D140N Mutant of Chitinase B from Serratia Marcescens at 1.45 A Resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1H9G
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FadR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI, in complex with myristoyl-CoA
分子名称: COENZYME A, FATTY ACID METABOLISM REGULATOR PROTEIN, MYRISTIC ACID
著者Van Aalten, D.M.F, Dirusso, C.C, Knudsen, J.
登録日2001-03-09
公開日2001-03-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structural Basis of Acyl Coenzyme A-Dependent Regulation of the Transcription Factor Fadr
Embo J., 20, 2001

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件を2024-10-30に公開中

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