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PDB: 1224 件

3RN8
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Crystal Structure of iGluR2 Ligand Binding Domain and Symmetrical Carboxyl Containing Potentiator
分子名称: 3,3'-benzene-1,4-diylbis(4-cyano-5-ethylthiophene-2-carboxylic acid), ACETATE ION, GLUTAMIC ACID, ...
著者Timm, D.E.
登録日2011-04-22
公開日2011-05-25
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.
Mol.Pharmacol., 80, 2011
3FBI
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Structure of the Mediator submodule Med7N/31
分子名称: Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7
著者Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P.
登録日2008-11-19
公開日2008-12-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
3REF
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Crystal structure of EhRho1 bound to GDP and Magnesium
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-like small GTPase, ...
著者Bosch, D.E, Qiu, C, Siderovski, D.P.
登録日2011-04-04
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.
J.Biol.Chem., 286, 2011
1NTG
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Crystal Structure of the EMAP II-like Cytokine Released from human tyrosyl-tRNA Synthetase
分子名称: Tyrosyl-tRNA synthetase
著者Yang, X.-L, Skene, R.J, Mcree, D.E, Schimmel, P.
登録日2003-01-29
公開日2003-05-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal Structure of an EMAP-II-like Cytokine Released from a human tRNA Synthetase
Helv.Chim.Acta, 86, 2003
1LOU
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RIBOSOMAL PROTEIN S6
分子名称: RIBOSOMAL PROTEIN S6
著者Otzen, D.E, Kristensen, O, Proctor, M, Oliveberg, M.
登録日1998-11-25
公開日1998-11-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots.
Biochemistry, 38, 1999
4KVD
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Crystal structure of Aspergillus terreus aristolochene synthase complexed with (4aS,7S)-1,4a-dimethyl-7-(prop-1-en-2-yl)decahydroquinolin-1-ium
分子名称: (1R,4aS,7S,8aR)-1,4a-dimethyl-7-(prop-1-en-2-yl)decahydroquinolinium, Aristolochene synthase, GLYCEROL, ...
著者Chen, M, Faraldos, J.A, Al-lami, N, Janvier, M, D'Antonio, E.L, Cane, D.E, Allemann, R.K, Christianson, D.W.
登録日2013-05-22
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
Biochemistry, 52, 2013
1L7O
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CRYSTAL STRUCTURE OF PHOSPHOSERINE PHOSPHATASE IN APO FORM
分子名称: ACETIC ACID, PHOSPHOSERINE PHOSPHATASE, ZINC ION
著者Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2002-03-16
公開日2002-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
3PDS
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Irreversible Agonist-Beta2 Adrenoceptor Complex
分子名称: 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, Fusion protein Beta-2 adrenergic receptor/Lysozyme, ...
著者Rosenbaum, D.M, Zhang, C, Lyons, J.A, Holl, R, Aragao, D, Arlow, D.H, Rasmussen, S.G.F, Choi, H.-J, DeVree, B.T, Sunahara, R.K, Chae, P.S, Gellman, S.H, Dror, R.O, Shaw, D.E, Weis, W.I, Caffrey, M, Gmeiner, P, Kobilka, B.K.
登録日2010-10-24
公開日2011-01-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
3PO7
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Human monoamine oxidase B in complex with zonisamide
分子名称: 1-(1,2-benzoxazol-3-yl)methanesulfonamide, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE
著者Binda, C, Aldeco, M, Mattevi, A, Edmondson, D.E.
登録日2010-11-22
公開日2011-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex
J.Med.Chem., 54, 2011
3FBN
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Structure of the Mediator submodule Med7N/31
分子名称: Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7
著者Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P.
登録日2008-11-19
公開日2008-12-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.007 Å)
主引用文献Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
3R7D
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Crystal Structure of Unliganded Aspartate Transcarbamoylase from Bacillus subtilis
分子名称: Aspartate carbamoyltransferase, PHOSPHATE ION
著者Puleo, D.E, Harris, K.M, Cockrell, G.M, Kantrowitz, E.R.
登録日2011-03-22
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Crystallographic Snapshots of the Complete Catalytic Cycle of the Unregulated Aspartate Transcarbamoylase from Bacillus subtilis.
J.Mol.Biol., 411, 2011
1NTR
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SOLUTION STRUCTURE OF THE N-TERMINAL RECEIVER DOMAIN OF NTRC
分子名称: NTRC RECEIVER DOMAIN
著者Volkman, B.F, Nohaile, M.J, Amy, N.K, Kustu, S, Wemmer, D.E.
登録日1994-09-16
公開日1995-01-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the N-terminal receiver domain of NTRC.
Biochemistry, 34, 1995
3RNN
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Crystal Structure of iGluR2 Ligand Binding Domain with Symmetric Sulfonamide Containing Potentiator
分子名称: GLUTAMIC ACID, Glutamate receptor 2, N,N'-(benzene-1,4-diyldiethane-2,1-diyl)dipropane-2-sulfonamide, ...
著者Timm, D.E.
登録日2011-04-22
公開日2011-05-25
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.
Mol.Pharmacol., 80, 2011
4L9M
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Autoinhibited state of the Ras-specific exchange factor RasGRP1
分子名称: CITRIC ACID, GLYCEROL, RAS guanyl-releasing protein 1, ...
著者Iwig, J.S, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J.G, Wemmer, D.E, Roose, J.P, Kuriyan, J.
登録日2013-06-18
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
1KFZ
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Solution Structure of C-terminal Sem-5 SH3 Domain (Ensemble of 16 Structures)
分子名称: SEX MUSCLE ABNORMAL PROTEIN 5
著者Ferreon, J.C, Volk, D.E, Luxon, B.A, Gorenstein, D, Hilser, V.J.
登録日2001-11-24
公開日2003-05-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble of Sem-5 C-Terminal SH3 Domain
Biochemistry, 42, 2003
4KWD
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Crystal structure of Aspergillus terreus aristolochene synthase complexed with (1R,8R,9aS)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium
分子名称: (1R,5R,8R,9aS)-1,9a-dimethyl-8-(prop-1-en-2-yl)octahydro-2H-quinolizinium, Aristolochene synthase, GLYCEROL, ...
著者Chen, M, Al-lami, N, Janvier, M, D'Antonio, E.L, Faraldos, J.A, Cane, D.E, Allemann, R.K, Christianson, D.W.
登録日2013-05-23
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.857 Å)
主引用文献Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
Biochemistry, 52, 2013
1KH0
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Accurate Computer Base Design of a New Backbone Conformation in the Second Turn of Protein L
分子名称: protein L
著者O'Neill, J.W, Kuhlman, B, Kim, D.E, Zhang, K.Y, Baker, D.
登録日2001-11-28
公開日2002-01-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Accurate computer-based design of a new backbone conformation in the second turn of protein L.
J.Mol.Biol., 315, 2002
3IOC
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Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.50 Ang resolution in complex with 5'-deoxy-5'-(benzyldisulfanyl)-adenosine
分子名称: (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(benzyldisulfanyl)methyl]tetrahydrofuran-3,4-diol, GLYCEROL, Pantothenate synthetase
著者Ciulli, A, Scott, D.E, Abell, C.
登録日2009-08-14
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry
Chembiochem, 10, 2009
3IOD
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Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.75 Ang resolution in complex with 5'-deoxy-5'-((3-nitrobenzyl)disulfanyl)-adenosine
分子名称: (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-{[(3-nitrobenzyl)disulfanyl]methyl}tetrahydrofuran-3,4-diol, ETHANOL, GLYCEROL, ...
著者Ciulli, A, Scott, D.E, Abell, C.
登録日2009-08-14
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry
Chembiochem, 10, 2009
4L4U
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Crystal structure of construct containing A. aeolicus NtrC1 receiver, central and DNA binding domains
分子名称: Transcriptional regulator (NtrC family)
著者Vidangos, N.K, Maris, A.E, Young, A, Hong, E, Pelton, J.G, Batchelor, J.D, Wemmer, D.E.
登録日2013-06-09
公開日2013-08-28
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure, function, and tethering of DNA-binding domains in sigma (54) transcriptional activators.
Biopolymers, 99, 2013
4N9R
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X-ray structure of the complex between hen egg white lysozyme and pentacholrocarbonyliridate(III) (1 day)
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION, ...
著者Petruk, A.A, Bikiel, D.E, Vergara, A, Merlino, A.
登録日2013-10-21
公開日2015-12-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Interaction between proteins and Ir based CO releasing molecules: mechanism of adduct formation and CO release.
Inorg.Chem., 53, 2014
1ONM
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Solution Structure of a DNA duplex containing A:G mismatch. d(GCTTCAGTCGT):d(ACGACGGAAGC)
分子名称: 5'-D(*AP*CP*GP*AP*CP*GP*GP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*CP*AP*GP*TP*CP*GP*T)-3'
著者Sanchez, A.M, Volk, D.E, Gorenstein, D.G, Lloyd, R.S.
登録日2003-02-28
公開日2003-11-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Initiation of repair of A/G mismatches is modulated by sequence context
DNA REPAIR, 2, 2003
1NNF
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Crystal Structure Analysis of Haemophlius Influenzae Ferric-ion Binding Protein H9Q Mutant Form
分子名称: FE (III) ION, Iron-utilization periplasmic protein, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID
著者Shouldice, S.R, Dougan, D.R, Skene, R.J, Tari, L.W, McRee, D.E, Yu, R.-H, Schryvers, A.B.
登録日2003-01-13
公開日2003-04-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High Resolution Structure of an Alternate Form of the Ferric ion Binding Protein from Haemophilus influenzae
J.Biol.Chem., 278, 2003
1NPZ
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Crystal structures of Cathepsin S inhibitor complexes
分子名称: Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide
著者Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L.
登録日2003-01-20
公開日2003-04-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
4HNX
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The NatA Acetyltransferase Complex Bound To ppGpp
分子名称: GUANOSINE-5',3'-TETRAPHOSPHATE, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1
著者Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D.
登録日2012-10-21
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility
To be Published

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件を2024-09-11に公開中

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