6WA2
| Crystal structure of EGFR(T790M/V948R) in complex with LN3753 | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-fluoro-5-hydroxybenzamide | 著者 | Heppner, D.E, Eck, M.J. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites. J.Med.Chem., 65, 2022
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6WAK
| A crystal structure of EGFR(T790M/V948R) in complex with LN3754 | 分子名称: | Epidermal growth factor receptor, MAGNESIUM ION, N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzamide, ... | 著者 | Heppner, D.E, Eck, M.J. | 登録日 | 2020-03-25 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites. J.Med.Chem., 65, 2022
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5L1Q
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5L1S
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5L1U
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5L8Z
| Structure of thermostable DNA-binding HU protein from micoplasma Spiroplasma melliferum | 分子名称: | DNA-binding protein, SODIUM ION | 著者 | Boyko, K.M, Gorbacheva, M.A, Rakitina, T.V, Korzhenevskiy, D.A, Kamashev, D.E, Vanyushkina, A.A, Lipkin, A.V, Popov, V.O. | 登録日 | 2016-06-09 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis of the high thermal stability of the histone-like HU protein from the mollicute Spiroplasma melliferum KC3. Sci Rep, 6, 2016
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5L6L
| Structure of Caulobacter crescentus VapBC1 bound to operator DNA | 分子名称: | DNA (27-MER), Ribonuclease VapC, VapB family protein | 著者 | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | 登録日 | 2016-05-30 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res., 45, 2017
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5L1T
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5L6M
| Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form) | 分子名称: | GLYCEROL, MALONATE ION, Ribonuclease VapC, ... | 著者 | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | 登録日 | 2016-05-30 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res., 45, 2017
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3NP1
| CRYSTAL STRUCTURE OF THE COMPLEX OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS WITH CYANIDE | 分子名称: | CYANIDE ION, NITROPHORIN 1, PHOSPHATE ION, ... | 著者 | Weichsel, A, Andersen, J.F, Champagne, D.E, Walker, F.A, Montfort, W.R. | 登録日 | 1998-01-22 | 公開日 | 1998-05-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of a nitric oxide transport protein from a blood-sucking insect. Nat.Struct.Biol., 5, 1998
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4HNW
| The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate | 分子名称: | INOSITOL HEXAKISPHOSPHATE, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1, ... | 著者 | Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D. | 登録日 | 2012-10-21 | 公開日 | 2014-03-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility To be Published
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1GK5
| Solution Structure the mEGF/TGFalpha44-50 chimeric growth factor | 分子名称: | Pro-epidermal growth factor,Protransforming growth factor alpha | 著者 | Chamberlin, S.G, Brennan, L, Puddicombe, S.M, Davies, D.E, Turner, D.L. | 登録日 | 2001-08-08 | 公開日 | 2002-08-08 | 最終更新日 | 2018-03-28 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Megf/Tgfalpha44-50 Chimeric Growth Factor. Eur.J.Biochem., 268, 2001
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1LN2
| Crystal Structure of Human Phosphatidylcholine Transfer Protein in Complex with Dilinoleoylphosphatidylcholine (Seleno-Met Protein) | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Phosphatidylcholine transfer protein | 著者 | Roderick, S.L, Chan, W.W, Agate, D.S, Olsen, L.R, Vetting, M.W, Rajashankar, K.R, Cohen, D.E. | 登録日 | 2002-05-02 | 公開日 | 2002-06-26 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat.Struct.Biol., 9, 2002
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4HNY
| Apo N-terminal acetyltransferase complex A | 分子名称: | GLYCEROL, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1, ... | 著者 | Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D. | 登録日 | 2012-10-21 | 公開日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | 主引用文献 | The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility To be Published
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4HJD
| GCN4pLI derivative with alpha/beta/acyclic-gamma amino acid substitution pattern | 分子名称: | GCN4pLI(alpha/beta/acyclic gamma) | 著者 | Shin, Y.H, Mortenson, D.E, Satyshur, K.A, Forest, K.T, Gellman, S.H. | 登録日 | 2012-10-12 | 公開日 | 2013-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water. J.Am.Chem.Soc., 135, 2013
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3FDQ
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4MCN
| Human SOD1 C57S Mutant, Metal-free | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn] | 著者 | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | 登録日 | 2013-08-21 | 公開日 | 2014-08-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J.Biol.Chem., 290, 2015
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4MIT
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1LIS
| THE CRYSTAL STRUCTURE OF A FERTILIZATION PROTEIN | 分子名称: | LYSIN | 著者 | Shaw, A, Mcree, D.E, Vacquier, V.D, Stout, C.D. | 登録日 | 1993-06-29 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of lysin, a fertilization protein. Science, 262, 1993
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4HJB
| GCN4pLI derivative with alpha/beta/cyclic-gamma amino acid substitution pattern | 分子名称: | GCN4pLI(alpha/beta/cyclic-gamma) | 著者 | Shin, Y.H, Mortenson, D.E, Satyshur, K.A, Forest, K.T, Gellman, S.H. | 登録日 | 2012-10-12 | 公開日 | 2013-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water. J.Am.Chem.Soc., 135, 2013
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1LW6
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1MP8
| Crystal structure of Focal Adhesion Kinase (FAK) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, focal adhesion kinase 1 | 著者 | Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C.G, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A. | 登録日 | 2002-09-11 | 公開日 | 2003-09-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography Structure, 10, 2002
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1MNA
| Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.0 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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1MNQ
| Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.4 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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3GT8
| Crystal structure of the inactive EGFR kinase domain in complex with AMP-PNP | 分子名称: | Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Jura, N, Endres, N.F, Engel, K, Deindl, S, Das, R, Lamers, M.H, Wemmer, D.E, Zhang, X, Kuriyan, J. | 登録日 | 2009-03-27 | 公開日 | 2009-07-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | 主引用文献 | Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell(Cambridge,Mass.), 137, 2009
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