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PDB: 1224 results

5W87
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BU of 5w87 by Molmil
Crystal structure of the C-terminal lobe of the human HERC6 HECT domain
Descriptor: PHOSPHATE ION, Probable E3 ubiquitin-protein ligase HERC6
Authors:WANG, Y, BELLESIS, A.G, ROYER, W.E, SPRATT, D.E.
Deposit date:2017-06-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structure of the C-terminal lobe of the human HERC6 HECT domain
To Be Published
5ZX5
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BU of 5zx5 by Molmil
3.3 angstrom structure of mouse TRPM7 with EDTA
Descriptor: CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7
Authors:Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E.
Deposit date:2018-05-18
Release date:2018-10-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1VLS
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BU of 1vls by Molmil
LIGAND BINDING DOMAIN OF THE WILD-TYPE ASPARTATE RECEPTOR
Descriptor: ASPARTATE RECEPTOR
Authors:Kim, S.-H, Yeh, J.I, Biemann, H.-P, Prive, G, Pandit, J, Koshland Junior, D.E.
Deposit date:1996-09-17
Release date:1997-04-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:High-resolution structures of the ligand binding domain of the wild-type bacterial aspartate receptor.
J.Mol.Biol., 262, 1996
1VLT
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BU of 1vlt by Molmil
LIGAND BINDING DOMAIN OF THE WILD-TYPE ASPARTATE RECEPTOR WITH ASPARTATE
Descriptor: ASPARTATE RECEPTOR, ASPARTIC ACID
Authors:Kim, S.-H, Yeh, J.I, Biemann, H.-P, Prive, G, Pandit, J, Koshland Junior, D.E.
Deposit date:1996-09-17
Release date:1997-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-resolution structures of the ligand binding domain of the wild-type bacterial aspartate receptor.
J.Mol.Biol., 262, 1996
1BOF
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BU of 1bof by Molmil
GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM
Descriptor: GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Coleman, D.E, Sprang, S.R.
Deposit date:1998-08-04
Release date:1999-01-06
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment.
Biochemistry, 37, 1998
6DU8
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BU of 6du8 by Molmil
Human Polycsytin 2-l1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein
Authors:Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J.
Deposit date:2018-06-20
Release date:2018-07-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Cryo-EM structure of the polycystin 2-l1 ion channel.
Elife, 7, 2018
5ED0
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BU of 5ed0 by Molmil
Structure of the Shigella flexneri VapC mutant D7N
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5DZ2
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BU of 5dz2 by Molmil
Geosmin synthase from Streptomyces coelicolor N-terminal domain complexed with three Mg2+ ions and alendronic acid
Descriptor: ALENDRONATE, Germacradienol/geosmin synthase, MAGNESIUM ION
Authors:Harris, G.G, Lombardi, P.M, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K.W, Cane, D.E, Christianson, D.W.
Deposit date:2015-09-25
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.111 Å)
Cite:Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Biochemistry, 54, 2015
5ECY
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BU of 5ecy by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 2
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-10-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri
to be published
5ECW
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BU of 5ecw by Molmil
Structure of the Shigella flexneri VapC mutant D7A
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
2QS4
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BU of 2qs4 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with LY466195 at 1.58 Angstroms resolution
Descriptor: (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, AMMONIUM ION, GLYCEROL, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
6DRH
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BU of 6drh by Molmil
ADP-ribosyltransferase toxin/immunity pair
Descriptor: ADP-ribosyl-(Dinitrogen reductase) hydrolase, MAGNESIUM ION, PAAR repeat-containing protein, ...
Authors:Bosch, D.E, Ting, S, Allaire, M, Mougous, J.D.
Deposit date:2018-06-11
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins.
Cell, 175, 2018
1EEM
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BU of 1eem by Molmil
GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS
Descriptor: GLUTATHIONE, GLUTATHIONE-S-TRANSFERASE, SULFATE ION
Authors:Board, P, Coggan, M, Chelvanayagam, G, Easteal, S, Jermiin, L.S, Schulte, G.K, Danley, D.E, Hoth, L.R, Griffor, M.C, Kamath, A.V, Rosner, M.H, Chrunyk, B.A, Perregaux, D.E, Gabel, C.A, Geoghegan, K.F, Pandit, J.
Deposit date:2000-02-01
Release date:2000-08-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification, characterization, and crystal structure of the Omega class glutathione transferases.
J.Biol.Chem., 275, 2000
6ICD
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BU of 6icd by Molmil
REGULATION OF AN ENZYME BY PHOSPHORYLATION AT THE ACTIVE SITE
Descriptor: ISOCITRATE DEHYDROGENASE
Authors:Hurley, J.H, Dean, A.M, Sohl, J.L, Koshlandjunior, D.E, Stroud, R.M.
Deposit date:1990-05-30
Release date:1991-10-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulation of an enzyme by phosphorylation at the active site.
Science, 249, 1990
2QS1
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BU of 2qs1 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution
Descriptor: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-4,5-dibromothiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
2QTX
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BU of 2qtx by Molmil
Crystal structure of an Hfq-like protein from Methanococcus jannaschii
Descriptor: Uncharacterized protein MJ1435
Authors:Nielsen, J.S, Boggild, A, Andersen, C.B.F, Nielsen, G, Boysen, A, Brodersen, D.E, Valentin-Hansen, P.
Deposit date:2007-08-03
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii.
Rna, 13, 2007
6DRE
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BU of 6dre by Molmil
ADP-ribosyltransferase toxin/immunity pair
Descriptor: ADP-ribosyl-(Dinitrogen reductase) hydrolase, MAGNESIUM ION, PAAR repeat-containing protein
Authors:Bosch, D.E, Ting, S, Allaire, M, Mougous, J.D.
Deposit date:2018-06-11
Release date:2018-10-31
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins.
Cell, 175, 2018
6DRW
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BU of 6drw by Molmil
JAK2 JH1 in complex with JNJ-7706621 (Crystal Form 2)
Descriptor: 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Tyrosine-protein kinase JAK2
Authors:Puleo, D.E, Schlessinger, J.
Deposit date:2018-06-13
Release date:2018-07-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:JAK2 JH2 Binders
To Be Published
2Q9Z
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BU of 2q9z by Molmil
Trichodiene synthase: Complex with inorganic pyrophosphate resulting from the reaction with 2-fluorofarnesyl diphosphate
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Vedula, L.S, Zhao, Y, Coates, R.M, Koyama, T, Cane, D.E, Christianson, D.W.
Deposit date:2007-06-14
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Exploring biosynthetic diversity with trichodiene synthase.
Arch.Biochem.Biophys., 466, 2007
1RYC
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BU of 1ryc by Molmil
CYTOCHROME C PEROXIDASE W191G FROM SACCHAROMYCES CEREVISIAE
Descriptor: BENZIMIDAZOLE, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fitzgerald, M.M, Musah, R, Mcree, D.E, Goodin, D.B.
Deposit date:1996-05-10
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
6HPB
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BU of 6hpb by Molmil
Crystal structure of the E.coli HicAB toxin-antitoxin complex
Descriptor: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
6GW6
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BU of 6gw6 by Molmil
Structure of the Pseudomonas putida RES-Xre toxin-antitoxin complex
Descriptor: GLYCEROL, IMIDAZOLE, RES toxin, ...
Authors:Senissar, M, Brodersen, D.E.
Deposit date:2018-06-22
Release date:2018-10-24
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD.
Mol. Microbiol., 111, 2019
6HPC
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BU of 6hpc by Molmil
Crystal structure of the HicB antitoxin from E. coli
Descriptor: Antitoxin HicB
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
1ZDM
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BU of 1zdm by Molmil
Crystal Structure of Activated CheY Bound to Xe
Descriptor: Chemotaxis protein cheY, MANGANESE (II) ION, XENON
Authors:Lowery, T.J, Doucleff, M, Ruiz, E.J, Rubin, S.M, Pines, A, Wemmer, D.E.
Deposit date:2005-04-14
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Distinguishing multiple chemotaxis Y protein conformations with laser-polarized 129Xe NMR.
Protein Sci., 14, 2005
6ZN8
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BU of 6zn8 by Molmil
Crystal structure of the H. influenzae VapXD toxin-antitoxin complex
Descriptor: Endoribonuclease VapD, VapX
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-07-06
Release date:2020-11-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021

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