5NFV
 
 | | Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ... | | 著者 | Swarts, D.C, van der Oost, J, Jinek, M. | | 登録日 | 2017-03-16 | | 公開日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
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4WZB
 | | Crystal Structure of MgAMPPCP-bound Av2-Av1 complex | | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (II) ION, FE(8)-S(7) CLUSTER, ... | | 著者 | Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. | | 登録日 | 2014-11-19 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Nitrogenase complexes: multiple docking sites for a nucleotide switch protein.
Science, 309, 2005
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1AO7
 | | COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201 | | 分子名称: | BETA-2 MICROGLOBULIN, ETHYL MERCURY ION, HLA-A 0201, ... | | 著者 | Garboczi, D.N, Ghosh, P, Utz, U, Fan, Q.R, Biddison, W.E, Wiley, D.C. | | 登録日 | 1997-07-21 | | 公開日 | 1997-09-17 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the complex between human T-cell receptor, viral peptide and HLA-A2.
Nature, 384, 1996
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1BFB
 | | BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN TETRAMER FRAGMENT | | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BASIC FIBROBLAST GROWTH FACTOR | | 著者 | Faham, S, Rees, D.C. | | 登録日 | 1995-12-12 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
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4HMG
 | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ... | | 著者 | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | | 登録日 | 1989-09-11 | | 公開日 | 1991-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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1BD2
 | | COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201 | | 分子名称: | BETA-2 MICROGLOBULIN, HLA-A 0201, T CELL RECEPTOR ALPHA, ... | | 著者 | Ding, Y.-H, Smith, K.J, Garboczi, D.N, Utz, U, Biddison, W.E, Wiley, D.C. | | 登録日 | 1998-05-12 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Immunity, 8, 1998
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1AFC
 | | STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR | | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR | | 著者 | Zhu, X, Hsu, B.T, Rees, D.C. | | 登録日 | 1993-07-13 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor.
Structure, 1, 1993
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1CHZ
 | | A NEW NEUROTOXIN FROM BUTHUS MARTENSII KARSCH | | 分子名称: | CHLORIDE ION, PROTEIN (BMK M2) | | 著者 | He, X.L, Deng, J.P, Li, H.M, Wang, D.C. | | 登録日 | 1999-03-31 | | 公開日 | 2000-03-31 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A.
Acta Crystallogr.,Sect.D, 56, 2000
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1AOR
 | | STRUCTURE OF A HYPERTHERMOPHILIC TUNGSTOPTERIN ENZYME, ALDEHYDE FERREDOXIN OXIDOREDUCTASE | | 分子名称: | ALDEHYDE FERREDOXIN OXIDOREDUCTASE, FE (III) ION, IRON/SULFUR CLUSTER, ... | | 著者 | Chan, M.K, Mukund, S, Kletzin, A, Adams, M.W.W, Rees, D.C. | | 登録日 | 1995-02-13 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase.
Science, 267, 1995
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1BFC
 | | BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT | | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BASIC FIBROBLAST GROWTH FACTOR | | 著者 | Faham, S, Rees, D.C. | | 登録日 | 1995-12-12 | | 公開日 | 1996-04-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
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4INS
 | | THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | | 分子名称: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | | 著者 | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | | 登録日 | 1989-07-10 | | 公開日 | 1990-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of 2Zn pig insulin crystals at 1.5 A resolution.
Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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6I1L
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6I1K
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6IBC
 | | Thermophage P23-45 procapsid | | 分子名称: | Major head protein | | 著者 | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | 登録日 | 2018-11-29 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.39 Å) | | 主引用文献 | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6IBG
 | | Bacteriophage G20c portal protein crystal structure for construct with intact N-terminus | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Portal protein | | 著者 | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | 登録日 | 2018-11-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6IYW
 | | Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct | | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, GLYCEROL, L,D-transpeptidase 2 | | 著者 | Li, D.F, Zhao, F, Wang, D.C. | | 登録日 | 2018-12-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
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6I9E
 | | Thermophage P23-45 empty expanded capsid | | 分子名称: | Auxiliary protein, Major head protein | | 著者 | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | 登録日 | 2018-11-23 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6IYV
 | | Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ertapenem adduct | | 分子名称: | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhao, F, Li, D.F, Wang, D.C. | | 登録日 | 2018-12-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
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6JFK
 | | GDP bound Mitofusin2 (MFN2) | | 分子名称: | CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | 登録日 | 2019-02-10 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6JFL
 | | Nucleotide-free Mitofusin2 (MFN2) | | 分子名称: | CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ... | | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | 登録日 | 2019-02-10 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6HJL
 | | Affimer:BclxL | | 分子名称: | Affimer ADB13, Bcl-2-like protein 1 | | 著者 | Miles, J.A, Trinh, C.H, Tomlinson, D.C, Wilson, A.J, Edwards, T.A. | | 登録日 | 2018-09-04 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs
Biorxiv, 2020
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6JFM
 | | Mitofusin2 (MFN2)_T111D | | 分子名称: | ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2 | | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | 登録日 | 2019-02-10 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6JMP
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7OMK
 | | The NMR structure of the Zf-GRF domains from the mouse Endonuclease VIII-LIKE 3 (mNEIL3) | | 分子名称: | Endonuclease 8-like 3 | | 著者 | Dinesh, D.C, Huskova, A, Srb, P, Veverka, V, Silhan, J. | | 登録日 | 2021-05-24 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model.
Nucleic Acids Res., 50, 2022
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7QSR
 | | CryoEM structure of the Ectodomain of Human PLA2R | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Briggs, D.C, Lockhart-Cairns, M.P, Baldock, C. | | 登録日 | 2022-01-14 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.
Proc.Natl.Acad.Sci.USA, 119, 2022
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