6JMP

Crystal Structure of a Non-hemolytic Pneumolysin from Streptococcus pneumoniae strain ST306

Summary for 6JMP

Entry DOI	10.2210/pdb6jmp/pdb
Descriptor	Thiol-activated cytolysin, GLYCEROL (3 entities in total)
Functional Keywords	cholesterol dependent cytolysin, toxin, pneumolysin, non-pore forming, non-hemolytic, membrane
Biological source	Streptococcus pneumoniae
Total number of polymer chains	1
Total formula weight	53129.24
Authors	Badgujar, D.C.,Bhaumik, P. (deposition date: 2019-03-13, release date: 2020-09-09, Last modification date: 2023-11-22)
Primary citation	Badgujar, D.C.,Anil, A.,Green, A.E.,Surve, M.V.,Madhavan, S.,Beckett, A.,Prior, I.A.,Godsora, B.K.,Patil, S.B.,More, P.K.,Sarkar, S.G.,Mitchell, A.,Banerjee, R.,Phale, P.S.,Mitchell, T.J.,Neill, D.R.,Bhaumik, P.,Banerjee, A. Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle. Plos Pathog., 16:e1009016-e1009016, 2020 Cited by PubMed: 33216805 DOI: 10.1371/journal.ppat.1009016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation