3UR4
 
 | | Crystal structure of human WD repeat domain 5 with compound | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | | Authors: | Dong, A, Dombrovski, L, Senisterra, G, Wernimont, A, Wasney, G.A, Allali Hassani, A, Nguyen, K.T, Smil, D, Bolshan, Y, Hajian, T, Poda, G, Chau, I, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2011-11-21 | | Release date: | 2011-12-14 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Biochem. J., 449, 2013
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1M5S
 | | Formylmethanofuran:tetrahydromethanopterin fromyltransferase from Methanosarcina barkeri | | Descriptor: | Formylmethanofuran--tetrahydromethanopterin formyltransferase | | Authors: | Mamat, B, Roth, A, Grimm, C, Ermler, U, Tziatzios, C, Schubert, D, Thauer, R.K, Shima, S. | | Deposit date: | 2002-07-10 | | Release date: | 2002-07-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structures and enzymatic properties of three formyltransferases from archaea: environmental adaptation and evolutionary relationship.
Protein Sci., 11, 2002
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1M1Q
 | | P222 oxidized structure of the tetraheme cytochrome c from Shewanella oneidensis MR1 | | Descriptor: | HEME C, SULFATE ION, small tetraheme cytochrome c | | Authors: | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | | Deposit date: | 2002-06-20 | | Release date: | 2002-08-14 | | Last modified: | 2021-03-03 | | Method: | X-RAY DIFFRACTION (0.97 Å) | | Cite: | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c
J.Biol.Chem., 277, 2002
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1M8A
 | | Human MIP-3alpha/CCL20 | | Descriptor: | ISOPROPYL ALCOHOL, Small inducible cytokine A20 | | Authors: | Hoover, D.M, Boulegue, C, Yang, D, Oppenheim, J.J, Tucker, K, Lu, W, Lubkowski, J. | | Deposit date: | 2002-07-24 | | Release date: | 2002-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins
J.Biol.Chem., 277, 2002
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1MFK
 | | Structure of Prokaryotic SECIS mRNA Hairpin | | Descriptor: | 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3' | | Authors: | Fourmy, D, Guittet, E, Yoshizawa, S. | | Deposit date: | 2002-08-12 | | Release date: | 2002-11-13 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB
J.Mol.Biol., 324, 2002
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1M72
 | | Crystal Structure of Caspase-1 from Spodoptera frugiperda | | Descriptor: | 1,2-ETHANEDIOL, Ace-Asp-Glu-Val-Asp-chloromethylketone, Caspase-1 | | Authors: | Forsyth, C.M, Lemongello, D, Friesen, P.D, Fisher, A.J. | | Deposit date: | 2002-07-18 | | Release date: | 2004-01-20 | | Last modified: | 2013-02-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of an invertebrate caspase.
J.Biol.Chem., 279, 2004
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1MBM
 | | NSP4 proteinase from Equine Arteritis Virus | | Descriptor: | chymotrypsin-like serine protease | | Authors: | Barrette-Ng, I.H, Ng, K.K.-S, Mark, B.L, van Aken, D, Cherney, M.M, Garen, C, Kolodenko, Y, Gorbalenya, A.E, Snijder, E.J, James, M.N.G. | | Deposit date: | 2002-08-03 | | Release date: | 2002-10-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Arterivirus nsp4: the smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole
J.Biol.Chem., 277, 2002
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1MC7
 | | Solution Structure of mDvl1 PDZ domain | | Descriptor: | Segment polarity protein dishevelled homolog DVL-1 | | Authors: | Wong, H.-C, Bourdelas, A, Shao, Y, Wu, D, Shi, D.L, Zheng, J. | | Deposit date: | 2002-08-05 | | Release date: | 2003-09-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
Mol.Cell, 12, 2003
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1ML4
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1MOF
 | | COAT PROTEIN | | Descriptor: | CHLORIDE ION, MOLONEY MURINE LEUKEMIA VIRUS P15 | | Authors: | Fass, D, Harrison, S.C, Kim, P.S. | | Deposit date: | 1996-04-02 | | Release date: | 1996-10-14 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Retrovirus envelope domain at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
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1MN4
 | | Structure of Ndt80 (Residues 59-340) DNA-binding domain core | | Descriptor: | NDT80 PROTEIN | | Authors: | Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M. | | Deposit date: | 2002-09-04 | | Release date: | 2002-11-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
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1MIO
 | | X-RAY CRYSTAL STRUCTURE OF THE NITROGENASE MOLYBDENUM-IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM AT 3.0 ANGSTROMS RESOLUTION | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE-MO-S CLUSTER, ... | | Authors: | Kim, J, Woo, D, Rees, D.C. | | Deposit date: | 1993-03-24 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystal structure of the nitrogenase molybdenum-iron protein from Clostridium pasteurianum at 3.0-A resolution.
Biochemistry, 32, 1993
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1MOZ
 | | ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae | | Descriptor: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A. | | Deposit date: | 2002-09-10 | | Release date: | 2002-10-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
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1MPV
 | | Structure of bhpBR3, the BAFF-binding loop of BR3 embedded in a beta-hairpin peptide | | Descriptor: | BLyS Receptor 3 | | Authors: | Kayagaki, N, Yan, M, Seshasayee, D, Wang, H, Lee, W, French, D.M, Grewal, I.S, Cochran, A.G, Gordon, N.C, Yin, J, Starovasnik, M.A, Dixit, V.M. | | Deposit date: | 2002-09-12 | | Release date: | 2002-10-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
Immunity, 17, 2002
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2SPC
 | | CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN | | Descriptor: | SPECTRIN | | Authors: | Yan, Y, Winograd, E, Viel, A, Cronin, T, Harrison, S.C, Branton, D. | | Deposit date: | 1994-03-01 | | Release date: | 1994-05-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the repetitive segments of spectrin.
Science, 262, 1993
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7NHT
 | | Akirin2 bound human proteasome | | Descriptor: | Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ... | | Authors: | Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D. | | Deposit date: | 2021-02-11 | | Release date: | 2021-09-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature, 599, 2021
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1NJ1
 | | Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to cysteine sulfamoyl adenylate | | Descriptor: | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ... | | Authors: | Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A. | | Deposit date: | 2002-12-30 | | Release date: | 2003-03-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
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7N86
 | | Crystal Structure of Human Protocadherin-24 EC1-2 Form II | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Modak, D, Gray, M.E, Sotomayor, M. | | Deposit date: | 2021-06-13 | | Release date: | 2021-09-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.175 Å) | | Cite: | Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Plos Biol., 19, 2021
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7NHI
 | | Crystal structure of the human METTL3-METTL14 complex with compound UOZ004 | | Descriptor: | (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl)piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... | | Authors: | Bedi, R.K, Huang, D, Caflisch, A. | | Deposit date: | 2021-02-10 | | Release date: | 2021-09-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Acs Bio Med Chem Au, 2023
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7NH4
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7NH5
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2TMG
 | | THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E | | Descriptor: | PROTEIN (GLUTAMATE DEHYDROGENASE) | | Authors: | Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R. | | Deposit date: | 1998-12-04 | | Release date: | 1999-12-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
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7NG7
 | | Src kinase bound to eCF506 trapped in inactive conformation | | Descriptor: | 1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Src, tert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)carbamate | | Authors: | Lietha, D, Unciti-Broceta, A. | | Deposit date: | 2021-02-08 | | Release date: | 2021-09-15 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
Cancer Res., 81, 2021
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7NQC
 | | Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane targeting motifs | | Descriptor: | CALCIUM ION, Calmodulin-1, PRO-ASN-GLY-LYS-LYS-LYS-ARG-LYS-SER-LEU-ALA-LYS-ARG-ILE-ARG-GLU-ARG-CMF, ... | | Authors: | Chamberlain, S.G, Owen, D, Mott, H.R. | | Deposit date: | 2021-03-01 | | Release date: | 2021-09-22 | | Method: | SOLUTION NMR | | Cite: | Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MZ5
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