7NT1
 
 | | Crystal structure of SARS CoV2 main protease in complex with FSP007 | | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, [(2R)-1-[2-(1H-indol-3-yl)ethylamino]-1-oxidanylidene-butan-2-yl] prop-2-enoate | | Authors: | Oerlemans, R, Eris, D, Wang, M, Sharpe, M, Domling, A, Groves, M.R. | | Deposit date: | 2021-03-08 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7NTV
 | | Crystal structure of SARS CoV2 main protease in complex with DN_EG_002 (modelled using PanDDA event map) | | Descriptor: | 2-acetamido-N-cyclopropyl-5-phenyl-thiophene-3-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE | | Authors: | Oerlemans, R, Eris, D, Wang, M, Sharpe, M, Domling, A, Groves, M.R. | | Deposit date: | 2021-03-10 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.065 Å) | | Cite: | Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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2PK8
 | | Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus | | Descriptor: | GOLD (I) CYANIDE ION, Uncharacterized protein PF0899 | | Authors: | Liu, Z.J, Tempel, W, Chen, L, Shah, A, Lee, D, Clancy-Kelley, L.L, Dillard, B.D, Rose, J.P, Sugar, F.J, Jenny Jr, F.E, Lee, H.S, Izumi, M, Shah, C, Poole III, F.L, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2007-04-17 | | Release date: | 2007-05-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution.
Acta Crystallogr.,Sect.F, 63, 2007
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7NT2
 | | Crystal structure of SARS CoV2 main protease in complex with FSP006 | | Descriptor: | 3C-like proteinase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Oerlemans, R, Eris, D, Wang, M, Sharpe, M, Domling, A, Groves, M.R. | | Deposit date: | 2021-03-08 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.145 Å) | | Cite: | Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification.
Angew.Chem.Int.Ed.Engl., 60, 2021
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1CTI
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1CUN
 | | CRYSTAL STRUCTURE OF REPEATS 16 AND 17 OF CHICKEN BRAIN ALPHA SPECTRIN | | Descriptor: | PROTEIN (ALPHA SPECTRIN) | | Authors: | Grum, V.L, Li, D, MacDonald, R.I, Mondragon, A. | | Deposit date: | 1999-08-20 | | Release date: | 1999-10-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of two repeats of spectrin suggest models of flexibility.
Cell(Cambridge,Mass.), 98, 1999
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2PMS
 | | Crystal structure of the complex of human lactoferrin N-lobe and lactoferrin-binding domain of pneumococcal surface protein A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | Authors: | Chattopadhyay, D, Senkovich, O, Cook, W.J. | | Deposit date: | 2007-04-23 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.
J.Mol.Biol., 370, 2007
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7P1K
 | | Cryo EM structure of bison NHA2 in nano disc structure | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2 | | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | Deposit date: | 2021-07-01 | | Release date: | 2022-01-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
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1CZ2
 | | SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2. | | Descriptor: | NONSPECIFIC LIPID TRANSFER PROTEIN, PROSTAGLANDIN B2 | | Authors: | Tassin-Moindrot, S, Caille, A, Douliez, J.-P, Marion, D, Vovelle, F. | | Deposit date: | 1999-09-01 | | Release date: | 2000-09-27 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | The wide binding properties of a wheat nonspecific lipid transfer protein. Solution structure of a complex with prostaglandin B2.
Eur.J.Biochem., 267, 2000
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2O84
 | | Crystal structure of K206E mutant of N-lobe human transferrin | | Descriptor: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | Authors: | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | | Deposit date: | 2006-12-12 | | Release date: | 2007-01-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
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7P1J
 | | Cryo EM structure of bison NHA2 in detergent structure | | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | Deposit date: | 2021-07-01 | | Release date: | 2022-01-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
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7P1I
 | | Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix | | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | | Deposit date: | 2021-07-01 | | Release date: | 2022-01-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2.
Nat.Struct.Mol.Biol., 29, 2022
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7P99
 | | Structure of human USPL1 in complex with SUMO2 | | Descriptor: | SUMO-specific isopeptidase USPL1, Small ubiquitin-related modifier, ZINC ION | | Authors: | Reverter, D, Ying, L. | | Deposit date: | 2021-07-26 | | Release date: | 2022-03-02 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1.
Nat Commun, 13, 2022
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1CJX
 | | CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS HPPD | | Descriptor: | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, ACETATE ION, ETHYL MERCURY ION, ... | | Authors: | Serre, L, Sailland, A, Sy, D, Boudec, P, Rolland, A, Pebay-Peroulla, E, Cohen-Addad, C. | | Deposit date: | 1999-04-20 | | Release date: | 2000-04-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.
Structure Fold.Des., 7, 1999
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2OHW
 | | Crystal structure of the YueI protein from Bacillus subtilis | | Descriptor: | YueI protein | | Authors: | Bonanno, J.B, Jin, X, Mu, H, Dickey, M, Bain, K.T, Wu, B, Chen, T, Reyes, C, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2007-01-10 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of the YueI protein from Bacillus subtilis
To be Published
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2NTG
 | | Structure of Spin-labeled T4 Lysozyme Mutant T115R7 | | Descriptor: | BETA-MERCAPTOETHANOL, Lysozyme, S-[(4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | Authors: | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | | Deposit date: | 2006-11-07 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
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2NTO
 | | Structure of the Glutathione Transferase from Ochrobactrum anthropi in complex with glutathione | | Descriptor: | GLUTATHIONE, SULFATE ION, glutathione S-transferase | | Authors: | Federici, L, Bonivento, D, Di Matteo, A, Allocati, N. | | Deposit date: | 2006-11-08 | | Release date: | 2007-09-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | Role of Ser11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase
Biochem.J., 403, 2007
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1CQF
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2NVZ
 | | RNA Polymerase II elongation complex with UTP, updated 11/2006 | | Descriptor: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | | Authors: | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | | Deposit date: | 2006-11-14 | | Release date: | 2006-12-19 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (4.3 Å) | | Cite: | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
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7OV8
 | | Crystal structure of pig purple acid phosphatase in complex with 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) and glycerol | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Feder, D, McGeary, R.P, Guddat, L.W, Schenk, G. | | Deposit date: | 2021-06-14 | | Release date: | 2022-03-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach.
Chemmedchem, 16, 2021
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1CQP
 | | CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION | | Descriptor: | ANTIGEN CD11A (P180), LOVASTATIN, MAGNESIUM ION | | Authors: | Kallen, J, Welzenbach, K, Ramage, P, Geyl, D, Kriwacki, R, Legge, G, Cottens, S, Weitz-Schmidt, G, Hommel, U. | | Deposit date: | 1999-08-10 | | Release date: | 2000-08-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
J.Mol.Biol., 292, 1999
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1CR5
 | | N-TERMINAL DOMAIN OF SEC18P | | Descriptor: | 1-ETHYL-PYRROLIDINE-2,5-DIONE, SEC18P (RESIDUES 22 - 210) | | Authors: | Babor, S.M, Fass, D. | | Deposit date: | 1999-08-13 | | Release date: | 1999-12-22 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the Sec18p N-terminal domain.
Proc.Natl.Acad.Sci.USA, 96, 1999
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2NY0
 | | HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | | Deposit date: | 2006-11-20 | | Release date: | 2007-02-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
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2O03
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2O2D
 | | Crystal structure of phosphoglucose isomerase from Trypanosoma brucei complexed with citrate | | Descriptor: | CITRIC ACID, GLYCEROL, Glucose-6-phosphate isomerase, ... | | Authors: | Arsenieva, D, Mazock, G.H, Appavu, B.L, Jeffery, C.J. | | Deposit date: | 2006-11-29 | | Release date: | 2007-11-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of phosphoglucose isomerase from Trypanosoma brucei complexed with glucose-6-phosphate at 1.6 A resolution
Proteins, 74, 2008
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