6GCR
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![BU of 6gcr by Molmil](/molmil-images/mine/6gcr) | Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor | 分子名称: | 2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide, Focal adhesion kinase 1 | 著者 | Yen-Pon, E, Li, B, Acebron-Garcia de Eulate, M, Tomkiewicz-Raulet, C, Dawson, J, Lietha, D, Frame, M.C, Coumoul, X, Garbay, C, Etheve-Quelquejeu, M, Chen, H. | 登録日 | 2018-04-19 | 公開日 | 2019-05-01 | 最終更新日 | 2019-10-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Characterization of the First Irreversible Inhibitor of Focal Adhesion Kinase. Acs Chem.Biol., 13, 2018
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6G9L
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![BU of 6g9l by Molmil](/molmil-images/mine/6g9l) | Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | 登録日 | 2018-04-11 | 公開日 | 2018-05-16 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (5.01 Å) | 主引用文献 | Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
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6GAW
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![BU of 6gaw by Molmil](/molmil-images/mine/6gaw) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. | 分子名称: | 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... | 著者 | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | 登録日 | 2018-04-13 | 公開日 | 2018-08-22 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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6TAC
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![BU of 6tac by Molmil](/molmil-images/mine/6tac) | Human NAMPT deletion mutant in complex with nicotinamide mononucleotide, pyrophosphate, and Mg2+ | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | 登録日 | 2019-10-29 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification of structural determinants of NAMPT activity and substrate selectivity To Be Published
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6T3A
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![BU of 6t3a by Molmil](/molmil-images/mine/6t3a) | Difference-refined structure of rsEGFP2 10 ns following 400-nm laser irradiation of the off-state determined by SFX | 分子名称: | Green fluorescent protein | 著者 | Woodhouse, J, Coquelle, N, Adam, V, Barends, T.R.M, De La Mora, E, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M. | 登録日 | 2019-10-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy. Nat Commun, 11, 2020
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3HV6
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![BU of 3hv6 by Molmil](/molmil-images/mine/3hv6) | Human p38 MAP Kinase in Complex with RL39 | 分子名称: | 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)phenyl]urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | 著者 | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | 登録日 | 2009-06-15 | 公開日 | 2009-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Displacement assay for the detection of stabilizers of inactive kinase conformations. J.Med.Chem., 53, 2010
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3I1U
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3HVZ
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![BU of 3hvz by Molmil](/molmil-images/mine/3hvz) | Crystal Structure of the TGS domain of the CLOLEP_03100 protein from Clostridium leptum, Northeast Structural Genomics Consortium Target QlR13A | 分子名称: | Uncharacterized protein | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-16 | 公開日 | 2009-06-23 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target QlR13A To be Published
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3I32
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3HZE
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![BU of 3hze by Molmil](/molmil-images/mine/3hze) | Crystal Structure of Ycf54 protein from Thermosynechococcus elongatus, Northeast Structural Genomics Consortium Target TeR59 | 分子名称: | PHOSPHATE ION, Ycf54 protein | 著者 | Kuzin, A, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-23 | 公開日 | 2009-07-07 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target TeR59 To be Published
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6TFD
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![BU of 6tfd by Molmil](/molmil-images/mine/6tfd) | Crystal structure of nitrite and NO bound three-domain copper-containing nitrite reductase from Hyphomicrobium denitrificans strain 1NES1 | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRIC OXIDE, ... | 著者 | Sasaki, D, Watanabe, T.F, Eady, R.R, Garratt, R.C, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2019-11-13 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes. Iucrj, 7, 2020
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6FWF
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![BU of 6fwf by Molmil](/molmil-images/mine/6fwf) | Low resolution structure of Neisseria meningitidis qNOR | 分子名称: | CALCIUM ION, FE (III) ION, Nitric-oxide reductase, ... | 著者 | Young, D, Antonyuk, S, Tosha, T, Hisano, T, Hasnain, S, Shiro, Y. | 登録日 | 2018-03-06 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Characterization of the quinol-dependent nitric oxide reductase from the pathogen Neisseria meningitidis, an electrogenic enzyme. Sci Rep, 8, 2018
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6GCG
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![BU of 6gcg by Molmil](/molmil-images/mine/6gcg) | Copper nitrite reductase from Achromobacter cycloclastes: large polymorph dataset 15 | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2018-04-17 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.80015242 Å) | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography. Acta Crystallogr D Struct Biol, 75, 2019
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3KV8
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![BU of 3kv8 by Molmil](/molmil-images/mine/3kv8) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK - Wild type FlK in complex with fluoro-acetate | 分子名称: | Fluoroacetyl-CoA thioesterase FlK, fluoroacetic acid | 著者 | Dias, M.V.B, Huang, F, Chirgadze, D.Y, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | 登録日 | 2009-11-29 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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6TL9
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![BU of 6tl9 by Molmil](/molmil-images/mine/6tl9) | CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 IN COMPLEX WITH BI-0115 | 分子名称: | 9-chloranyl-5-propyl-11~{H}-pyrido[2,3-b][1,4]benzodiazepin-6-one, GLYCEROL, Oxidized low-density lipoprotein receptor 1 | 著者 | Nar, H, Fiegen, D, Schnapp, G. | 登録日 | 2019-12-02 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.734 Å) | 主引用文献 | A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state Commun Chem, 2020
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3KSD
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![BU of 3ksd by Molmil](/molmil-images/mine/3ksd) | Crystal Structure of C151S+H178N mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1) from Staphylococcus aureus MRSA252 complexed with NAD at 2.2 angstrom resolution | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Mukherjee, S, Dutta, D, Saha, B, Das, A.K. | 登録日 | 2009-11-22 | 公開日 | 2010-08-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
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3KX9
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3KV3
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![BU of 3kv3 by Molmil](/molmil-images/mine/3kv3) | Crystal structure of C151S mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH 1)from methicillin resistant Staphylococcus aureus MRSA252 complexed with NAD and G3P | 分子名称: | 3-PHOSPHOGLYCERIC ACID, GAPDH, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Mukherjee, S, Dutta, D, Saha, B, Das, A.K. | 登録日 | 2009-11-29 | 公開日 | 2010-08-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
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3KVV
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![BU of 3kvv by Molmil](/molmil-images/mine/3kvv) | Trapping of an oxocarbenium ion intermediate in UP crystals | 分子名称: | 1,4-anhydro-D-erythro-pent-1-enitol, 5-FLUOROURACIL, SULFATE ION, ... | 著者 | Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. | 登録日 | 2009-11-30 | 公開日 | 2010-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
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3KX7
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![BU of 3kx7 by Molmil](/molmil-images/mine/3kx7) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA FlK - apo wild type FlK | 分子名称: | Fluoroacetyl-CoA thioesterase FlK | 著者 | Dias, M.V.B, Huang, F, Chirgadze, D.Y, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | 登録日 | 2009-12-02 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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6FXU
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6GAA
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![BU of 6gaa by Molmil](/molmil-images/mine/6gaa) | BACTERIORHODOPSIN, 430 FS STATE, REAL-SPACE REFINED AGAINST 15% EXTRAPOLATED STRUCTURE FACTORS | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Schlichting, I. | 登録日 | 2018-04-11 | 公開日 | 2019-04-24 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin. Nat Commun, 10, 2019
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3KZN
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![BU of 3kzn by Molmil](/molmil-images/mine/3kzn) | Crystal structure of N-acetyl-L-ornithine transcarbamylase complexed with N-acetyl-L-ornirthine | 分子名称: | GLYCEROL, N-acetylornithine carbamoyltransferase, N~2~-ACETYL-L-ORNITHINE, ... | 著者 | Shi, D, Yu, X, Allewell, N.M, Tuchman, M. | 登録日 | 2009-12-08 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of N-acetylornithine transcarbamoylase from Xanthomonas campestris complexed with substrates and substrate analogs imply mechanisms for substrate binding and catalysis. Proteins, 64, 2006
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6GB8
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![BU of 6gb8 by Molmil](/molmil-images/mine/6gb8) | Copper nitrite reductase from Achromobacter cycloclastes: small cell polymorph dataset 1 | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, NITRITE ION | 著者 | Ebrahim, A, Appleby, M.V, Axford, D, Beale, J, Moreno-Chicano, T, Sherrell, D.A, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2018-04-13 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography. Acta Crystallogr D Struct Biol, 75, 2019
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3L05
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![BU of 3l05 by Molmil](/molmil-images/mine/3l05) | Crystal structure of N-acetyl-L-ornithine transcarbamylase E92S mutant complexed with carbamyl phosphate and N-succinyl-L-norvaline | 分子名称: | N-(3-CARBOXYPROPANOYL)-L-NORVALINE, N-acetylornithine carbamoyltransferase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... | 著者 | Shi, D, Yu, X, Allewell, N.M, Tuchman, M. | 登録日 | 2009-12-09 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase. Protein Sci., 16, 2007
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