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PDB: 22202 件

3UR4
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Crystal structure of human WD repeat domain 5 with compound
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Dong, A, Dombrovski, L, Senisterra, G, Wernimont, A, Wasney, G.A, Allali Hassani, A, Nguyen, K.T, Smil, D, Bolshan, Y, Hajian, T, Poda, G, Chau, I, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-11-21
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5.
Biochem. J., 449, 2013
1M5S
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Formylmethanofuran:tetrahydromethanopterin fromyltransferase from Methanosarcina barkeri
分子名称: Formylmethanofuran--tetrahydromethanopterin formyltransferase
著者Mamat, B, Roth, A, Grimm, C, Ermler, U, Tziatzios, C, Schubert, D, Thauer, R.K, Shima, S.
登録日2002-07-10
公開日2002-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures and enzymatic properties of three formyltransferases from archaea: environmental adaptation and evolutionary relationship.
Protein Sci., 11, 2002
1M1Q
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P222 oxidized structure of the tetraheme cytochrome c from Shewanella oneidensis MR1
分子名称: HEME C, SULFATE ION, small tetraheme cytochrome c
著者Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J.
登録日2002-06-20
公開日2002-08-14
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c
J.Biol.Chem., 277, 2002
1M8A
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Human MIP-3alpha/CCL20
分子名称: ISOPROPYL ALCOHOL, Small inducible cytokine A20
著者Hoover, D.M, Boulegue, C, Yang, D, Oppenheim, J.J, Tucker, K, Lu, W, Lubkowski, J.
登録日2002-07-24
公開日2002-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins
J.Biol.Chem., 277, 2002
1MFK
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Structure of Prokaryotic SECIS mRNA Hairpin
分子名称: 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3'
著者Fourmy, D, Guittet, E, Yoshizawa, S.
登録日2002-08-12
公開日2002-11-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB
J.Mol.Biol., 324, 2002
1M72
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Crystal Structure of Caspase-1 from Spodoptera frugiperda
分子名称: 1,2-ETHANEDIOL, Ace-Asp-Glu-Val-Asp-chloromethylketone, Caspase-1
著者Forsyth, C.M, Lemongello, D, Friesen, P.D, Fisher, A.J.
登録日2002-07-18
公開日2004-01-20
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an invertebrate caspase.
J.Biol.Chem., 279, 2004
1MBM
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NSP4 proteinase from Equine Arteritis Virus
分子名称: chymotrypsin-like serine protease
著者Barrette-Ng, I.H, Ng, K.K.-S, Mark, B.L, van Aken, D, Cherney, M.M, Garen, C, Kolodenko, Y, Gorbalenya, A.E, Snijder, E.J, James, M.N.G.
登録日2002-08-03
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Arterivirus nsp4: the smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole
J.Biol.Chem., 277, 2002
1MC7
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Solution Structure of mDvl1 PDZ domain
分子名称: Segment polarity protein dishevelled homolog DVL-1
著者Wong, H.-C, Bourdelas, A, Shao, Y, Wu, D, Shi, D.L, Zheng, J.
登録日2002-08-05
公開日2003-09-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
Mol.Cell, 12, 2003
1ML4
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The PALA-liganded Aspartate transcarbamoylase catalytic subunit from Pyrococcus abyssi
分子名称: Aspartate Transcarbamoylase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Van Boxstael, S, Cunin, R, Maes, D.
登録日2002-08-30
公開日2003-02-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Aspartate Transcarbamylase from the Hyperthermophilic Archaeon Pyrococcus abyssi: Thermostability and 1.8A Resolution Crystal Structure of the Catalytic Subunit Complexed With the Bisubstrate Analogue N-Phosphonacetyl-L-aspartate.
J.Mol.Biol., 326, 2003
1MOF
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COAT PROTEIN
分子名称: CHLORIDE ION, MOLONEY MURINE LEUKEMIA VIRUS P15
著者Fass, D, Harrison, S.C, Kim, P.S.
登録日1996-04-02
公開日1996-10-14
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Retrovirus envelope domain at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
1MN4
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Structure of Ndt80 (Residues 59-340) DNA-binding domain core
分子名称: NDT80 PROTEIN
著者Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M.
登録日2002-09-04
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
1MIO
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X-RAY CRYSTAL STRUCTURE OF THE NITROGENASE MOLYBDENUM-IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM AT 3.0 ANGSTROMS RESOLUTION
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE-MO-S CLUSTER, ...
著者Kim, J, Woo, D, Rees, D.C.
登録日1993-03-24
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of the nitrogenase molybdenum-iron protein from Clostridium pasteurianum at 3.0-A resolution.
Biochemistry, 32, 1993
1MOZ
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ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae
分子名称: ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE
著者Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A.
登録日2002-09-10
公開日2002-10-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structures of Yeast ARF2 and ARL1: DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
1MPV
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Structure of bhpBR3, the BAFF-binding loop of BR3 embedded in a beta-hairpin peptide
分子名称: BLyS Receptor 3
著者Kayagaki, N, Yan, M, Seshasayee, D, Wang, H, Lee, W, French, D.M, Grewal, I.S, Cochran, A.G, Gordon, N.C, Yin, J, Starovasnik, M.A, Dixit, V.M.
登録日2002-09-12
公開日2002-10-30
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
Immunity, 17, 2002
2SPC
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BU of 2spc by Molmil
CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN
分子名称: SPECTRIN
著者Yan, Y, Winograd, E, Viel, A, Cronin, T, Harrison, S.C, Branton, D.
登録日1994-03-01
公開日1994-05-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the repetitive segments of spectrin.
Science, 262, 1993
7NHT
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Akirin2 bound human proteasome
分子名称: Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ...
著者Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D.
登録日2021-02-11
公開日2021-09-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature, 599, 2021
1NJ1
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Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to cysteine sulfamoyl adenylate
分子名称: 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ...
著者Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A.
登録日2002-12-30
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
7N86
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Crystal Structure of Human Protocadherin-24 EC1-2 Form II
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Modak, D, Gray, M.E, Sotomayor, M.
登録日2021-06-13
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.175 Å)
主引用文献Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Plos Biol., 19, 2021
7NHI
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Crystal structure of the human METTL3-METTL14 complex with compound UOZ004
分子名称: (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl)piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ...
著者Bedi, R.K, Huang, D, Caflisch, A.
登録日2021-02-10
公開日2021-09-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Acs Bio Med Chem Au, 2023
7NH4
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Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7NH5
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Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
2TMG
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THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E
分子名称: PROTEIN (GLUTAMATE DEHYDROGENASE)
著者Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R.
登録日1998-12-04
公開日1999-12-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
7NG7
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Src kinase bound to eCF506 trapped in inactive conformation
分子名称: 1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Src, tert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)carbamate
著者Lietha, D, Unciti-Broceta, A.
登録日2021-02-08
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
Cancer Res., 81, 2021
7NQC
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Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane targeting motifs
分子名称: CALCIUM ION, Calmodulin-1, PRO-ASN-GLY-LYS-LYS-LYS-ARG-LYS-SER-LEU-ALA-LYS-ARG-ILE-ARG-GLU-ARG-CMF, ...
著者Chamberlain, S.G, Owen, D, Mott, H.R.
登録日2021-03-01
公開日2021-09-22
実験手法SOLUTION NMR
主引用文献Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MZ5
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Cryo-EM structure of RTX-bound full-length TRPV1 in C2 state
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021

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件を2024-07-17に公開中

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