6HEV
 
 | | Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative AT061 | | 分子名称: | 4-methyl-3-[(2-pyridin-3-ylpyrido[2,3-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2 | | 著者 | Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H. | | 登録日 | 2018-08-20 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Effects of NVP-BHG712 chemical modifications on EPHA2 binding and affinity
To Be Published
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6H9N
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1KJK
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6KXE
 | | The ishigamide ketosynthase/chain length factor | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Ketosynthase, ... | | 著者 | Du, D, Katsuyama, Y, Horiuchi, M, Fushinobu, S, Chen, A, Davis, T, Burkart, M, Ohnishi, Y. | | 登録日 | 2019-09-10 | | 公開日 | 2020-05-06 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural basis for selectivity in a highly reducing type II polyketide synthase.
Nat.Chem.Biol., 16, 2020
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6KO0
 | | The crystal structue of PDE10A complexed with 1i | | 分子名称: | 3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Huang, Y.-Y, Yu, Y.F, Zhang, C, Guo, L, Wu, D, Luo, H.-B. | | 登録日 | 2019-08-07 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.600029 Å) | | 主引用文献 | Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors.
Acs Chem Neurosci, 11, 2020
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1KEX
 | | Crystal Structure of the b1 Domain of Human Neuropilin-1 | | 分子名称: | Neuropilin-1 | | 著者 | Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G. | | 登録日 | 2001-11-18 | | 公開日 | 2003-01-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
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1KOG
 | | Crystal structure of E. coli threonyl-tRNA synthetase interacting with the essential domain of its mRNA operator | | 分子名称: | 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, Threonyl-tRNA synthetase, Threonyl-tRNA synthetase mRNA, ... | | 著者 | Torres-Larrios, A, Dock-Bregeon, A.C, Romby, P, Rees, B, Sankaranarayanan, R, Caillet, J, Springer, M, Ehresmann, C, Ehresmann, B, Moras, D. | | 登録日 | 2001-12-20 | | 公開日 | 2002-04-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of translational control by Escherichia coli threonyl tRNA synthetase.
Nat.Struct.Biol., 9, 2002
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1KIJ
 | | Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin | | 分子名称: | DNA GYRASE SUBUNIT B, FORMIC ACID, NOVOBIOCIN | | 著者 | Lamour, V, Hoermann, L, Jeltsch, J.-M, Oudet, P, Moras, D. | | 登録日 | 2001-12-03 | | 公開日 | 2002-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An open conformation of the Thermus thermophilus gyrase B ATP-binding domain.
J.Biol.Chem., 277, 2002
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6KO1
 | | The crystal structue of PDE10A complexed with 2d | | 分子名称: | 6-chloranyl-3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Huang, Y.-Y, Yu, Y.F, Zhang, C, Guo, L, Wu, D, Luo, H.-B. | | 登録日 | 2019-08-07 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors.
Acs Chem Neurosci, 11, 2020
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6KP7
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1ILX
 | | Excited State Dynamics in Photosystem II Revised. New Insights from the X-ray Structure. | | 分子名称: | 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, CADMIUM ION, CHLOROPHYLL A, ... | | 著者 | Vasilev, S, Orth, P, Zouni, A, Owens, T.G, Bruce, D. | | 登録日 | 2001-05-09 | | 公開日 | 2001-07-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Excited-state dynamics in photosystem II: insights from the x-ray crystal structure.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1ISR
 | | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion | | 分子名称: | GADOLINIUM ATOM, GLUTAMIC ACID, Metabotropic Glutamate Receptor subtype 1 | | 著者 | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | | 登録日 | 2001-12-21 | | 公開日 | 2002-03-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1ITY
 | | Solution structure of the DNA binding domain of human TRF1 | | 分子名称: | TRF1 | | 著者 | Nishikawa, T, Okamura, H, Nagadoi, A, Konig, P, Rhodes, D, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-02-15 | | 公開日 | 2002-03-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a telomeric DNA complex of human TRF1
Structure, 9, 2001
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1IXZ
 | | Crystal structure of the FtsH ATPase domain from Thermus thermophilus | | 分子名称: | ATP-dependent metalloprotease FtsH, MERCURY (II) ION, SULFATE ION | | 著者 | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | | 登録日 | 2002-07-10 | | 公開日 | 2002-11-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8
Structure, 10, 2002
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6L02
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6KP2
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3SQJ
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4MT6
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6JQV
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1IO2
 | | Crystal structure of type 2 ribonuclease h from hyperthermophilic archaeon, thermococcus kodakaraensis kod1 | | 分子名称: | RIBONUCLEASE HII | | 著者 | Muroya, A, Tsuchiya, D, Ishikawa, M, Haruki, M, Morikawa, M. | | 登録日 | 2000-12-28 | | 公開日 | 2001-04-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Catalytic center of an archaeal type 2 ribonuclease H as revealed by X-ray crystallographic and mutational analyses.
Protein Sci., 10, 2001
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6J15
 | | Complex structure of GY-5 Fab and PD-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | | 著者 | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2018-12-27 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
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3T58
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6J7E
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1JJ9
 | | Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition | | 分子名称: | 2-HYDROXY-5-[4-(2-HYDROXY-ETHYL)-PIPERIDIN-1-YL]-5-PHENYL-1H-PYRIMIDINE-4,6-DIONE, CALCIUM ION, Matrix Metalloproteinase 8, ... | | 著者 | Brandstetter, H, Grams, F, Glitz, D, Lang, A, Huber, R, Bode, W, Krell, H.-W, Engh, R.A. | | 登録日 | 2001-07-04 | | 公開日 | 2001-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition.
J.Biol.Chem., 276, 2001
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6JB3
 | | Structure of SUR1 subunit bound with repaglinide | | 分子名称: | ATP-binding cassette sub-family C member 8 isoform X2, Digitonin, Repaglinide | | 著者 | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
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