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PDB: 22202 件

6IZV
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Averaged strand structure of a 15-stranded ParM filament from Clostridium botulinum
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative plasmid segregation protein ParM
著者Koh, F, Narita, A, Lee, L.J, Tan, Y.Z, Dandey, V.P, Tanaka, K, Popp, D, Robinson, R.C.
登録日2018-12-20
公開日2019-06-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structure of a 15-stranded actin-like filament from Clostridium botulinum.
Nat Commun, 10, 2019
6JHR
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The cryo-EM structure of HAV bound to a neutralizing antibody-F6
分子名称: FAB Heavy Chain, FAB Light Chain, VP1, ...
著者Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X.
登録日2019-02-18
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
8DJG
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ADGRL3-lectin domain in complex with an activating synthetic antibody fragment
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoform 2 of Adhesion G protein-coupled receptor L3, ...
著者Kordon, S.P, Bandekar, S.J, Arac, D.
登録日2022-06-30
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
Nat Commun, 14, 2023
6JMF
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Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 4
分子名称: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide, SULFATE ION, Tyrosine-protein kinase Fes/Fps
著者Baba, D, Hanzawa, H.
登録日2019-03-08
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity.
Acs Med.Chem.Lett., 10, 2019
6IWG
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Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with N-myristoylated 4-mer lipopeptide derived from SIV nef protein
分子名称: 1,2-ETHANEDIOL, BORIC ACID, Beta-2-microglobulin, ...
著者Yamamoto, Y, Morita, D, Sugita, M.
登録日2018-12-05
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification and Structure of an MHC Class I-Encoded Protein with the Potential to PresentN-Myristoylated 4-mer Peptides to T Cells.
J Immunol., 202, 2019
1JPE
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Crystal structure of DsbD-alpha; the N-terminal domain of DsbD
分子名称: DsbD-alpha
著者Haebel, P.W, Goldstone, D, Metcalf, P.
登録日2001-08-02
公開日2002-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC-DsbD alpha complex.
Embo J., 21, 2002
6IXW
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BU of 6ixw by Molmil
pCBH ParM non-polymerisable quadruple mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, pCBH ParM
著者Koh, F, Popp, D, Narita, A, Robinson, R.C.
登録日2018-12-12
公開日2019-06-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.253 Å)
主引用文献The structure of a 15-stranded actin-like filament from Clostridium botulinum.
Nat Commun, 10, 2019
4LJC
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Structure of an X-ray-induced photobleached state of IrisFP
分子名称: Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION
著者Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D.
登録日2013-07-04
公開日2013-10-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
7PDO
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BU of 7pdo by Molmil
Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 5.5 in complex with UDP
分子名称: CHLORIDE ION, Glucosyl-3-phosphoglycerate synthase, URIDINE-5'-DIPHOSPHATE
著者Silva, A, Nunes-Costa, D, Barbosa Pereira, P.J, Macedo-Ribeiro, S.
登録日2021-08-05
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 5.5 in complex with UDP
To Be Published
6JF1
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Crystal structure of the substrate binding protein of a methionine transporter from Streptococcus pneumoniae
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Jha, B, Vyas, R, Bhushan, J, Sehgal, D, Biswal, B.K.
登録日2019-02-07
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into the substrate specificity of SP_0149, the substrate-binding protein of a methionine ABC transporter from Streptococcus pneumoniae.
Acta Crystallogr.,Sect.F, 75, 2019
7PHO
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Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 7.1 in complex with 4-hydroxybenzaldehyde
分子名称: BICARBONATE ION, D-MALATE, GLYCEROL, ...
著者Nunes-Costa, D, Silva, A, Barbosa Pereira, P.J, Macedo-Ribeiro, S.
登録日2021-08-17
公開日2023-03-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 7.1 in complex with 4-hydroxybenzaldehyde
To Be Published
7PVL
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BU of 7pvl by Molmil
Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 8.5 - apo form
分子名称: CHLORIDE ION, Glucosyl-3-phosphoglycerate synthase, MAGNESIUM ION
著者Silva, A, Nunes-Costa, D, Barbosa Pereira, P.J, Macedo-Ribeiro, S.
登録日2021-10-04
公開日2023-04-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structure of Mycobacterium hassiacum glucosyl-3-phosphoglycerate synthase at pH 8.5 - apo form
To Be Published
6JDI
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BU of 6jdi by Molmil
Central domain of FleQ H287N mutant in complex with ATPgS and Mg
分子名称: MAGNESIUM ION, Nitrogen assimilation regulatory protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Jain, D, Banerjee, P, Chanchal
登録日2019-02-01
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Sensor I Regulated ATPase Activity of FleQ Is Essential for Motility to Biofilm Transition inPseudomonas aeruginosa.
Acs Chem.Biol., 14, 2019
6JDL
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BU of 6jdl by Molmil
Central domain of FleQ H287A mutant in complex with ATPgS and Mg
分子名称: MAGNESIUM ION, Nitrogen assimilation regulatory protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Jain, D, Banerjee, P, Chanchal
登録日2019-02-01
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.249 Å)
主引用文献Sensor I Regulated ATPase Activity of FleQ Is Essential for Motility to Biofilm Transition inPseudomonas aeruginosa.
Acs Chem.Biol., 14, 2019
8DB3
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BU of 8db3 by Molmil
Crystal structure of KaiC with truncated C-terminal coiled-coil domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC
著者Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
登録日2022-06-14
公開日2023-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献From primordial clocks to circadian oscillators.
Nature, 616, 2023
6JHQ
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BU of 6jhq by Molmil
The cryo-EM structure of HAV bound to a neutralizing antibody-F4
分子名称: FAB Heavy Chain, FAB Light Chain, VP1, ...
著者Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X.
登録日2019-02-18
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
6JHT
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BU of 6jht by Molmil
The cryo-EM structure of HAV bound to a neutralizing antibody-F9
分子名称: FAB Heavy Chain, FAB Light Chain, VP1, ...
著者Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X.
登録日2019-02-19
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
1JTP
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BU of 1jtp by Molmil
Degenerate interfaces in antigen-antibody complexes
分子名称: FORMIC ACID, LYSOZYME C, SODIUM ION, ...
著者Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L.
登録日2001-08-21
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001
1JUJ
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Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, THYMIDYLATE SYNTHASE
著者Sayre, P.H, Finer-Moore, J.S, Fritz, T.A, Biermann, D, Gates, S.B, MacKellar, W.C, Patel, V.F, Stroud, R.M.
登録日2001-08-24
公開日2001-09-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases.
J.Mol.Biol., 313, 2001
7Q97
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BU of 7q97 by Molmil
Structure of the bacterial type VI secretion system effector RhsA.
分子名称: Rhs family protein
著者Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S.
登録日2021-11-12
公開日2021-12-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of a bacterial Rhs effector exported by the type VI secretion system.
Plos Pathog., 18, 2022
8DBA
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BU of 8dba by Molmil
Crystal structure of dodecameric KaiC
分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION
著者Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
登録日2022-06-14
公開日2023-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献From primordial clocks to circadian oscillators.
Nature, 616, 2023
6JBJ
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Cryo-EM structure of human lysosomal cobalamin exporter ABCD4
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4
著者Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y.
登録日2019-01-25
公開日2019-09-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structure of human lysosomal cobalamin exporter ABCD4.
Cell Res., 29, 2019
6JBW
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Structure of Tps1/UDP complex
分子名称: Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE
著者Wang, S, Zhao, Y, Wang, D, Liu, J.
登録日2019-01-26
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
8CW2
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BU of 8cw2 by Molmil
Crystal structure of TDP1 complexed with compound XZ760
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-({(4R)-7-phenyl-2-[4-(2-{[4-(pyridin-2-yl)phenyl]methoxy}ethyl)phenyl]imidazo[1,2-a]pyridin-3-yl}amino)benzene-1,2-dicarboxylic acid, ...
著者Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R.
登録日2022-05-18
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.811 Å)
主引用文献Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification.
Rsc Chem Biol, 4, 2023
8CVQ
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BU of 8cvq by Molmil
Crystal structure of TDP1 complexed with compound XZ761
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid, ...
著者Lountos, G.T, Zhao, X.Z, Wang, W, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R.
登録日2022-05-18
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification.
Rsc Chem Biol, 4, 2023

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件を2024-07-17に公開中

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