1Y9Z
 
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3ZZK
 | | Structure of an engineered aspartate aminotransferase | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, GLYCEROL, ... | | 著者 | Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C. | | 登録日 | 2011-09-01 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
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1Y8J
 | | Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor | | 分子名称: | 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Sahli, S, Frank, B, Schweizer, W.B, Diederich, F, Blum-Kaelin, D, Aebi, J.D, Bohm, H.J, Oefner, C, Dale, G.E. | | 登録日 | 2004-12-13 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-ray Crystal Structure Analysis
HELV.CHIM.ACTA, 88, 2005
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1YF0
 | | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | | 分子名称: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | | 著者 | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | | 登録日 | 2004-12-29 | | 公開日 | 2005-08-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
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1XUU
 | | Crystal structure of sialic acid synthase (NeuB) in complex with Mn2+ and Malate from Neisseria meningitidis | | 分子名称: | D-MALATE, MANGANESE (II) ION, polysialic acid capsule biosynthesis protein SiaC | | 著者 | Gunawan, J, Simard, D, Gilbert, M, Lovering, A.L, Wakarchuk, W.W, Tanner, M.E, Strynadka, N.C. | | 登録日 | 2004-10-26 | | 公開日 | 2004-11-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.
J.Biol.Chem., 280, 2005
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1XXM
 | | The modular architecture of protein-protein binding site | | 分子名称: | Beta-lactamase TEM, Beta-lactamase inhibitory protein, CALCIUM ION | | 著者 | Reichmann, D, Rahat, O, Albeck, S, Meged, R, Dym, O, Schreiber, G, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2004-11-07 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The modular architecture of protein-protein binding interfaces
Proc.Natl.Acad.Sci.USA, 102, 2005
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5OF1
 | | The structural versatility of TasA in B. subtilis biofilm formation | | 分子名称: | 2-HYDROXYBENZOIC ACID, Spore coat-associated protein N, ethane-1,2-diol | | 著者 | Roske, Y, Diehl, A, Ball, L, Chowdhury, A, Hiller, M, Moliere, N, Kramer, R, Nagaraj, M, Stoeppler, D, Worth, C.L, Schlegel, B, Leidert, M, Cremer, N, Eisenmenger, F, Lopez, D, Schmieder, P, Heinemann, U, Turgay, K, Akbey, U, Oschkinat, H. | | 登録日 | 2017-07-10 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural changes of TasA in biofilm formation ofBacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1XFN
 | | NMR structure of the ground state of the photoactive yellow protein lacking the N-terminal part | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | 著者 | Bernard, C, Houben, K, Derix, N.M, Marks, D, van der Horst, M.A, Hellingwerf, K.J, Boelens, R, Kaptein, R, van Nuland, N.A. | | 登録日 | 2004-09-15 | | 公開日 | 2005-08-16 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of a transient photoreceptor intermediate: delta25 photoactive yellow protein
STRUCTURE, 13, 2005
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1XH4
 | | Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | | 分子名称: | N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | | 登録日 | 2004-09-17 | | 公開日 | 2005-09-17 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants
J.Med.Chem., 48, 2005
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1XSA
 | | Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant) | | 分子名称: | Bis(5'-nucleosyl)-tetraphosphatase | | 著者 | Swarbrick, J.D, Buyya, S, Gunawardana, D, Gayler, K.R, McLennan, A.G, Gooley, P.R. | | 登録日 | 2004-10-18 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
J.Biol.Chem., 280, 2005
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1XVQ
 | | Crystal structure of thiol peroxidase from Mycobacterium tuberculosis | | 分子名称: | AMMONIUM ION, YTTRIUM (III) ION, thiol peroxidase | | 著者 | Rho, B.S, Pedelacq, J.D, Hung, L.W, Holton, J.M, Vigil, D, Kim, S.I, Park, M.S, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2004-10-28 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Functional and Structural Characterization of a Thiol Peroxidase from Mycobacterium tuberculosis.
J.Mol.Biol., 361, 2006
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1XN0
 | | Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R,S)-Rolipram | | 分子名称: | MAGNESIUM ION, ROLIPRAM, ZINC ION, ... | | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | | 登録日 | 2004-10-04 | | 公開日 | 2004-12-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
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6TDH
 | | Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 1 | | 分子名称: | 3-(2-chlorophenyl)-4~{H}-1,2,4-triazole, ACETYL COENZYME *A, Glucosamine 6-phosphate N-acetyltransferase | | 著者 | Raimi, O.G, Stanley, M, Lockhart, D. | | 登録日 | 2019-11-08 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Targeting a critical step in fungal hexosamine biosynthesis.
J.Biol.Chem., 295, 2020
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1XOX
 | | SOLUTION STRUCTURE OF HUMAN SURVIVIN | | 分子名称: | Apoptosis inhibitor survivin, ZINC ION | | 著者 | Sun, C, Nettesheim, D, Liu, Z, Olejniczak, E.T. | | 登録日 | 2004-10-07 | | 公開日 | 2005-01-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human survivin and its binding interface with smac/diablo
Biochemistry, 44, 2005
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6TEI
 | | Crystal structure of human protein kinase CK2alpha (CSNK2A1 gene product) in complex with the 2-aminothiazole-type inhibitor 17 | | 分子名称: | 3-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]benzoic acid, Casein kinase II subunit alpha, SULFATE ION | | 著者 | Niefind, K, Lindenblatt, D, Jose, J, Applegate, V.M, Nickelsen, A. | | 登録日 | 2019-11-12 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.756 Å) | | 主引用文献 | Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2.
J.Med.Chem., 63, 2020
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1XPM
 | | Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... | | 著者 | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | | 登録日 | 2004-10-08 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47, 2004
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1XQO
 | | Crystal structure of native Pa-AGOG, 8-oxoguanine DNA glycosylase from Pyrobaculum aerophilum | | 分子名称: | 8-oxoguanine DNA glycosylase | | 著者 | Lingaraju, G.M, Sartori, A.A, Kostrewa, D, Prota, A.E, Jiricny, J, Winkler, F.K. | | 登録日 | 2004-10-13 | | 公開日 | 2004-11-16 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
Structure, 13, 2005
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1XXJ
 | | Urate oxidase from aspergillus flavus complexed with 5-amino 6-nitro uracil | | 分子名称: | 5-AMINO-6-NITROPYRIMIDINE-2,4(1H,3H)-DIONE, BENZENE, Uricase | | 著者 | Retailleau, P, Colloc'h, N, Vivares, D, Bonnete, F, Castro, B, El Hajji, M, Prange, T. | | 登録日 | 2004-11-05 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site.
Acta Crystallogr.,Sect.D, 61, 2005
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1XI0
 | | X-ray crystal structure of wild-type Xerocomus chrysenteron lectin XCL | | 分子名称: | lectin | | 著者 | Birck, C, Damian, L, Marty-Detraves, C, Lougarre, A, Schulze-Briese, C, Koehl, P, Fournier, D, Paquereau, L, Samama, J.P. | | 登録日 | 2004-09-21 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A new lectin family with structure similarity to actinoporins revealed by the crystal structure of Xerocomus chrysenteron lectin XCL
J.Mol.Biol., 344, 2004
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6S13
 | | Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22). | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | | 登録日 | 2019-06-18 | | 公開日 | 2019-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
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1XMK
 | | The Crystal structure of the Zb domain from the RNA editing enzyme ADAR1 | | 分子名称: | CADMIUM ION, CHLORIDE ION, Double-stranded RNA-specific adenosine deaminase, ... | | 著者 | Athanasiadis, A, Placido, D, Maas, S, Brown II, B.A, Lowenhaupt, K, Rich, A. | | 登録日 | 2004-10-03 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.
J.Mol.Biol., 351, 2005
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431D
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1XP0
 | | Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Vardenafil | | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, MAGNESIUM ION, ZINC ION, ... | | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | | 登録日 | 2004-10-07 | | 公開日 | 2004-12-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
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1XQF
 | | The mechanism of ammonia transport based on the crystal structure of AmtB of E. coli. | | 分子名称: | ACETATE ION, Probable ammonium transporter, SULFATE ION | | 著者 | Zheng, L, Kostrewa, D, Berneche, S, Winkler, F.K, Li, X.-D. | | 登録日 | 2004-10-12 | | 公開日 | 2004-10-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli
Proc.Natl.Acad.Sci.USA, 101, 2004
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4CBV
 | | X-ray structure of full-length ComE from Streptococcus pneumoniae. | | 分子名称: | COME | | 著者 | Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | | 登録日 | 2013-10-16 | | 公開日 | 2014-02-12 | | 最終更新日 | 2014-05-14 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae.
Nucleic Acids Res., 42, 2014
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