Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 56047 results

4RM2
DownloadVisualize
BU of 4rm2 by Molmil
Crystal structure of a benzoate coenzyme A ligase with 2-Fluoro benzoic acid
Descriptor: 2-fluorobenzoic acid, Benzoate-coenzyme A ligase
Authors:Strom, S, Nosrati, M, Thornburg, C, Walker, K.D, Geiger, J.H.
Deposit date:2014-10-18
Release date:2015-09-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Kinetically and Crystallographically Guided Mutations of a Benzoate CoA Ligase (BadA) Elucidate Mechanism and Expand Substrate Permissivity.
Biochemistry, 54, 2015
7TPJ
DownloadVisualize
BU of 7tpj by Molmil
Single-Particle Cryo-EM Structure of the WaaL O-antigen ligase in its apo state
Descriptor: Fab Heavy (H) Chain, Fab Light (L) Chain, Putative cell surface polysaccharide polymerase/ligase
Authors:Ashraf, K.U, Nygaard, R, Vickery, O.N, Erramilli, S.K, Herrera, C.M, McConville, T.H, Petrou, V.I, Giacometti, S.I, Dufrisne, M.B, Nosol, K, Zinkle, A.P, Graham, C.L.B, Loukeris, M, Kloss, B, Skorupinska-Tudek, K, Swiezewska, E, Roper, D, Clarke, O.B, Uhlemann, A.C, Kossiakoff, A.A, Trent, M.S, Stansfeld, P.J, Mancia, F.
Deposit date:2022-01-25
Release date:2022-04-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural basis of lipopolysaccharide maturation by the O-antigen ligase.
Nature, 604, 2022
7BFG
DownloadVisualize
BU of 7bfg by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, V37A mutant.
Descriptor: 30S ribosomal protein S6,30S ribosomal protein S6
Authors:Wang, H, Logan, D.T, Oliveberg, M.
Deposit date:2021-01-02
Release date:2022-07-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Circular permutant of ribosomal protein S6
To Be Published
7BFC
DownloadVisualize
BU of 7bfc by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated,
Descriptor: 30S ribosomal protein S6,30S ribosomal protein S6
Authors:Wang, H, Logan, D.T, Oliveberg, M.
Deposit date:2021-01-02
Release date:2022-07-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Circular permutant of ribosomal protein S6
To Be Published
6N86
DownloadVisualize
BU of 6n86 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein
Descriptor: Synembryn-A
Authors:Srivastava, D, Gakhar, L, Artemyev, N.O.
Deposit date:2018-11-28
Release date:2019-07-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6QYP
DownloadVisualize
BU of 6qyp by Molmil
Structure of Mcl-1 in complex with compound 13
Descriptor: (2~{R})-2-[5-[3-chloranyl-2-methyl-5-(4-methylpiperazin-1-yl)-4-oxidanyl-phenyl]-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A.
Deposit date:2019-03-09
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity.
J.Med.Chem., 62, 2019
6QZ5
DownloadVisualize
BU of 6qz5 by Molmil
Structure of Mcl-1 in complex with compound 8a
Descriptor: (2~{R})-2-[[6-ethyl-5-(1~{H}-indol-4-yl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A.
Deposit date:2019-03-11
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity.
J.Med.Chem., 62, 2019
6N5G
DownloadVisualize
BU of 6n5g by Molmil
Crystal structure of an epoxide hydrolase from Trichoderma reesei in complex with inhibitor 2
Descriptor: 4-[(quinolin-3-yl)methyl]-N-[4-(trifluoromethoxy)phenyl]piperidine-1-carboxamide, Epoxide hydrolase TrEH
Authors:Oliveira, G.S, Adriani, P.P, Ribeiro, J.A, Morisseau, C, Hammock, B.D, Dias, M.V, Chambergo, F.S.
Deposit date:2018-11-21
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors.
Int. J. Biol. Macromol., 129, 2019
4UJ7
DownloadVisualize
BU of 4uj7 by Molmil
Structure of the S-layer protein SbsC, domains 5-6
Descriptor: CALCIUM ION, SURFACE LAYER PROTEIN
Authors:Dordic, A, Pavkov-Keller, T, Eder, M, Egelseer, E.M, Davis, K, Mills, D, Sleytr, U.B, Kuehlbrandt, W, Vonck, J, Keller, W.
Deposit date:2015-04-08
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structure of the S-Layer Protein Sbsc, Domains 5-6
To be Published
5I0K
DownloadVisualize
BU of 5i0k by Molmil
Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases
Descriptor: CROTONYL COENZYME A, Phthiocerol synthesis polyketide synthase type I PpsC
Authors:Faille, A, Mourey, L, Pedelacq, J.D.
Deposit date:2016-02-04
Release date:2017-08-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases.
J. Mol. Biol., 429, 2017
7BFF
DownloadVisualize
BU of 7bff by Molmil
Circular permutant of ribosomal protein S6, P54-55 truncated, I25A mutant.
Descriptor: 30S ribosomal protein S6,30S ribosomal protein S6
Authors:Wang, H, Logan, D.T, Oliveberg, M.
Deposit date:2021-01-02
Release date:2022-07-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Circular permutant of ribosomal protein S6
To Be Published
1XI8
DownloadVisualize
BU of 1xi8 by Molmil
Molybdenum cofactor biosynthesis protein from Pyrococcus furiosus Pfu-1657500-001
Descriptor: Molybdenum cofactor biosynthesis protein
Authors:Zhou, W, Zhao, M, Chang, J.C, Liu, Z.-J, Chen, L, Horanyi, P, Xu, H, Yang, H, Habel, J.E, Lee, D, Chang, S.-H, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-21
Release date:2004-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Molybdenum cofactor biosynthesis protein from Pyrococcus furiosus Pfu-1657500-001
To be published
8HTB
DownloadVisualize
BU of 8htb by Molmil
Staphylococcus aureus FtsZ 12-316 complexed with TXH9179
Descriptor: 3-[(6-ethynyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Bryan, E, Ferrer-Gonzalez, E, Sagong, H.Y, Fujita, J, Mark, L, Kaul, M, LaVoie, E.J, Matsumura, H, Pilch, D.S.
Deposit date:2022-12-21
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus.
Acs Chem.Biol., 18, 2023
6QZ6
DownloadVisualize
BU of 6qz6 by Molmil
Structure of Mcl-1 in complex with compound 8b
Descriptor: (2~{R})-2-[[6-ethyl-5-(1~{H}-indol-4-yl)thieno[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Dokurno, P, Szlavik, Z, Ondi, L, Csekei, M, Paczal, A, Szabo, Z.B, Radics, G, Murray, J, Davidson, J, Chen, I, Davis, B, Hubbard, R.E, Pedder, C, Surgenor, A.E, Smith, J, Robertson, A, LeToumelin-Braizat, G, Cauquil, N, Zarka, M, Demarles, D, Perron-Sierra, F, Geneste, O, Kotschy, A.
Deposit date:2019-03-11
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity.
J.Med.Chem., 62, 2019
5I9B
DownloadVisualize
BU of 5i9b by Molmil
Caspase 3 V266A
Descriptor: ACE-ASP-GLU-VAL-ASK, Caspase-3, SODIUM ION
Authors:Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C.
Deposit date:2016-02-19
Release date:2016-10-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection.
Proc.Natl.Acad.Sci.USA, 113, 2016
5APZ
DownloadVisualize
BU of 5apz by Molmil
Thermosinus carboxydivorans Nor1 Tcar0761 residues 68-101 and 191-211 fused to GCN4 adaptors
Descriptor: GENERAL CONTROL PROTEIN GCN4, NOR1 TCAR0761
Authors:Hartmann, M.D, Deiss, S, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2015-09-17
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:alpha / beta coiled coils.
Elife, 5, 2016
1XAX
DownloadVisualize
BU of 1xax by Molmil
NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae
Descriptor: Hypothetical UPF0054 protein HI0004
Authors:Yeh, D.C, Parsons, J.F, Parsons, L.M, Liu, F, Eisenstein, E, Orban, J, Structure 2 Function Project (S2F)
Deposit date:2004-08-26
Release date:2005-01-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae, and comparison with the X-ray structure of an Aquifex aeolicus homolog
Protein Sci., 14, 2005
6QZ4
DownloadVisualize
BU of 6qz4 by Molmil
Structure of MHETase from Ideonella sakaiensis
Descriptor: CALCIUM ION, Mono(2-hydroxyethyl) terephthalate hydrolase, SULFATE ION
Authors:Allen, M.D, Johnson, C.W, Knott, B.C, Beckham, G.T, McGeehan, J.E.
Deposit date:2019-03-11
Release date:2020-09-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization and engineering of a two-enzyme system for plastics depolymerization.
Proc.Natl.Acad.Sci.USA, 117, 2020
5WUC
DownloadVisualize
BU of 5wuc by Molmil
Structural basis for conductance through TRIC cation channels
Descriptor: SODIUM ION, Uncharacterized protein
Authors:Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2016-12-17
Release date:2017-07-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for conductance through TRIC cation channels.
Nat Commun, 8, 2017
7T2S
DownloadVisualize
BU of 7t2s by Molmil
Structure of E. coli upec-117 Cap18 3'-5' exonuclease
Descriptor: 3'-5' exonuclease, ACETATE ION
Authors:Liang, Q, Richey, S.T, Ye, Q, Lau, R.K, Corbett, K.D.
Deposit date:2021-12-06
Release date:2022-07-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure and activity of a bacterial defense-associated 3'-5' exonuclease.
Protein Sci., 31, 2022
6ZHN
DownloadVisualize
BU of 6zhn by Molmil
3D electron diffraction structure of thaumatin from Thaumatococcus daniellii
Descriptor: CHLORIDE ION, Thaumatin-1
Authors:Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P.
Deposit date:2020-06-23
Release date:2021-01-27
Last modified:2024-10-16
Method:ELECTRON CRYSTALLOGRAPHY (2.76 Å)
Cite:Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
6YSU
DownloadVisualize
BU of 6ysu by Molmil
Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2025-03-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6QN3
DownloadVisualize
BU of 6qn3 by Molmil
Structure of the Glutamine II Riboswitch
Descriptor: BROMIDE ION, GLUTAMINE, MAGNESIUM ION, ...
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2019-02-08
Release date:2019-06-12
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and ligand binding of the glutamine-II riboswitch.
Nucleic Acids Res., 47, 2019
8FD9
DownloadVisualize
BU of 8fd9 by Molmil
Structure of BTK kinase domain with the second-generation inhibitor acalabrutinib
Descriptor: 4-[(4S)-8-amino-3-{(2S)-1-[(2E)-but-2-enoyl]pyrrolidin-2-yl}imidazo[1,5-a]pyrazin-1-yl]-N-(pyridin-2-yl)benzamide, BROMIDE ION, Tyrosine-protein kinase BTK
Authors:Lin, D.Y, Andreotti, A.H.
Deposit date:2022-12-02
Release date:2023-07-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.
Plos One, 18, 2023
6QN7
DownloadVisualize
BU of 6qn7 by Molmil
Structure of bovine anti-RSV hybrid Fab B4HC-B13LC
Descriptor: Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13
Authors:Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019

236371

數據於2025-05-21公開中

PDB statisticsPDBj update infoContact PDBjnumon