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PDB: 52974 件

1TFZ
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Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
分子名称: (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION
著者Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
登録日2004-05-27
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1JWW
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NMR characterization of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis
分子名称: Potential copper-transporting ATPase
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, D'Onofrio, M, Gonnelli, L, Marhuenda-Egea, F, Ruiz-Duenas, F.J.
登録日2001-09-05
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis in the apo and Cu(I) loaded states.
J.Mol.Biol., 317, 2002
5KDL
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Crystal structure of the 4 alanine insertion variant of the Gi alpha1 subunit bound to GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION
著者Kaya, A.I, Lokits, A.D, Gilbert, J, Iverson, T.M, Meiler, J, Hamm, H.E.
登録日2016-06-08
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.665 Å)
主引用文献A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.
J.Biol.Chem., 291, 2016
4IEB
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Crystal Structure of a Gly128Met mutant of the toxoplasma CDPK, TGME49_101440
分子名称: CALCIUM ION, Calmodulin-domain protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wernimont, A.K, Artz, J.D, El Bakkouri, M, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Hui, R, Amani, M, Structural Genomics Consortium (SGC)
登録日2012-12-13
公開日2013-12-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of a Gly128Met mutant of the toxoplasma CDPK, TGME49_101440
To be Published
3EUD
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Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p
分子名称: Protein SHQ1
著者Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J.
登録日2008-10-09
公開日2008-11-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1.
J.Biol.Chem., 284, 2009
1K02
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Crystal Structure of Old Yellow Enzyme Mutant Gln114Asn
分子名称: FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, NADPH DEHYDROGENASE 1
著者Brown, B.J, Hyun, J, Duvvuri, S.D, Karplus, P.A, Massey, V.
登録日2001-09-18
公開日2001-09-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The role of glutamine 114 in old yellow enzyme
J.Biol.Chem., 277, 2002
3EUV
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Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP
分子名称: (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ...
著者Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K.
登録日2008-10-11
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Analysis of the eukaryotic prenylome by isoprenoid affinity tagging
Nat.Chem.Biol., 5, 2009
4R8E
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Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Yersinia pestis
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Himiari, Z, Nanson, J.D, Swarbrick, C.M.D, Forwood, J.K.
登録日2014-09-02
公開日2014-12-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
Sci Rep, 5, 2015
1JTE
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Crystal Structure Analysis of VP39 F180W mutant
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, VP39
著者Hu, G, Oguro, A, Gershon, P.D, Quiocho, F.A.
登録日2001-08-20
公開日2002-07-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap.
Biochemistry, 41, 2002
1SXJ
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Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ...
著者Bowman, G.D, O'Donnell, M, Kuriyan, J.
登録日2004-03-30
公開日2004-06-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature, 429, 2004
2IRV
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Crystal structure of GlpG, a rhomboid intramembrane serine protease
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, DODECYL-BETA-D-MALTOSIDE, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者Bibi, E, Fass, D, Ben-Shem, A.
登録日2006-10-16
公開日2006-10-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for intramembrane proteolysis by rhomboid serine proteases.
Proc.Natl.Acad.Sci.Usa, 104, 2007
6IKG
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Crystal structure of substrate-bound S9 peptidase (S514A mutant) from Deinococcus radiodurans
分子名称: Acyl-peptide hydrolase, putative, GLYCEROL, ...
著者Yadav, P, Kumar, A, Goyal, V.D, Makde, R.D.
登録日2018-10-16
公開日2018-11-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms.
J.Biol.Chem., 294, 2019
2ITF
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Crystal structure IsdA NEAT domain from Staphylococcus aureus with heme bound
分子名称: Iron-regulated surface determinant protein A, PROTOPORPHYRIN IX CONTAINING FE
著者Grigg, J.C, Vermeiren, C.L, Heinrichs, D.E, Murphy, M.E.
登録日2006-10-19
公開日2006-12-26
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Haem recognition by a Staphylococcus aureus NEAT domain.
Mol.Microbiol., 63, 2007
6W2E
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Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
著者Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
登録日2020-03-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
2IUR
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BU of 2iur by Molmil
CRYSTAL STRUCTURE OF N-QUINOL FORM OF AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS, FORM A COCRYSTAL
分子名称: AROMATIC AMINE DEHYDROGENASE ALPHA SUBUNIT, AROMATIC AMINE DEHYDROGENASE BETA SUBUNIT
著者Roujeinikova, A, Scrutton, N, Leys, D.
登録日2006-06-07
公開日2006-09-20
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Atomic Level Insight Into the Oxidative Half-Reaction of Aromatic Amine Dehydrogenase.
J.Biol.Chem., 281, 2006
3ZKV
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Importin13 cytosolic state
分子名称: CADMUS
著者Gruenwald, M, Lazzaretti, D, Bono, F.
登録日2013-01-24
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
1T2F
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Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid
分子名称: 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
登録日2004-04-21
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
5KA6
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HIV-1 gp41 variant Q552R and L555M resistance mutations
分子名称: Transmembrane protein gp41
著者Bhardwaj, A, Khasnis, M.D, Halkidis, K, Root, M.J.
登録日2016-06-01
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
PLoS Pathog., 12, 2016
5K9B
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Azotobacter vinelandii Flavodoxin II
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin-2, MAGNESIUM ION
著者Rees, D.C, Segal, H.M, Spatzal, T.
登録日2016-05-31
公開日2017-08-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.174 Å)
主引用文献Electrochemical and structural characterization of Azotobacter vinelandii flavodoxin II.
Protein Sci., 26, 2017
1JR8
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Crystal Structure of Erv2p
分子名称: Erv2 PROTEIN, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者Gross, E, Sevier, C.S, Vala, A, Kaiser, C.A, Fass, D.
登録日2001-08-13
公開日2001-12-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.
Nat.Struct.Biol., 9, 2002
4RC1
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Structure of the methanofuran/methanopterin biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii with PRPP
分子名称: PHOSPHATE ION, UPF0264 protein MJ1099
著者Bobik, T.A, Morales, E.J, Cascio, D, Sawaya, M.R, Yeates, T.O, Rasche, M.E.
登録日2014-09-14
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii.
Acta Crystallogr F Struct Biol Commun, 70, 2014
5KDD
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Apo-structure of humanised RadA-mutant humRadA22
分子名称: DNA repair and recombination protein RadA, SULFATE ION
著者Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-08
公開日2016-10-19
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
3EKL
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Structural Characterization of tetrameric Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase - substrate binding and catalysis mechanism of a class IIa bacterial aldolase
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, SODIUM ION, ...
著者Pegan, S, Rukseree, K, Franzblau, S.G, Mesecar, A.D.
登録日2008-09-19
公開日2009-02-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
J.Mol.Biol., 386, 2009
2J4E
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THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE
分子名称: INOSINE 5'-TRIPHOSPHATE, INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINIC ACID, ...
著者Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmbergschiavone, L, Hogbom, M, Kotenyova, T, Landry, R, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Schuler, H, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-08-29
公開日2006-09-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
3EIE
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Crystal Structure of S.cerevisiae Vps4 in the SO4-bound state
分子名称: SULFATE ION, Vacuolar protein sorting-associated protein 4
著者Gonciarz, M.D, Whitby, F.G, Eckert, D.M, Kieffer, C, Heroux, A, Sundquist, W.I, Hill, C.P.
登録日2008-09-15
公開日2008-09-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Biochemical and structural studies of yeast vps4 oligomerization.
J.Mol.Biol., 384, 2008

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