1JMW
 
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4IOY
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6VVE
 | | Legionella pneumophila Lpg2603 kinase bound to IP6, Mn2+, and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Tomchick, D.R, Tagliabracci, V.S, Park, B.C. | | 登録日 | 2020-02-17 | | 公開日 | 2020-04-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | ALegionellaeffector kinase is activated by host inositol hexakisphosphate.
J.Biol.Chem., 295, 2020
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1SSW
 | | Crystal structure of phage T4 lysozyme mutant Y24A/Y25A/T26A/I27A/C54T/C97A | | 分子名称: | BETA-MERCAPTOETHANOL, Lysozyme | | 著者 | He, M.M, Baase, W.A, Xiao, H, Heinz, D.W, Matthews, B.W. | | 登録日 | 2004-03-24 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation
Protein Sci., 13, 2004
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4IOH
 | | Crystal Structure of the Tll1086 protein from Thermosynechococcus elongatus, Northeast Structural Genomics Consortium Target TeR258 | | 分子名称: | Tll1086 protein | | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, X, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2013-01-07 | | 公開日 | 2013-01-30 | | 最終更新日 | 2013-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Crystal Structure of the Tll1086 protein from Thermosynechococcus elongatus.
To be Published
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7ZQA
 | | VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=3* VLP) | | 分子名称: | VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR | | 著者 | Kingston, N.J, Grehan, K, Snowden, J.S, Alzahrani, J, Ranson, N.A, Rowlands, D.J, Stonehouse, N.J. | | 登録日 | 2022-04-29 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | VelcroVax: a "Bolt-On" Vaccine Platform for Glycoprotein Display.
Msphere, 8, 2023
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4R4Q
 | | Crystal structure of RPA70N in complex with 5-(3-((N-(4-(5-carboxyfuran-2-yl)benzyl)acetamido)methyl)phenyl)-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid | | 分子名称: | 5-[4-({acetyl[4-(5-carboxyfuran-2-yl)benzyl]amino}methyl)phenyl]-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit | | 著者 | Feldkamp, M.D, Waterson, A.G, Kennedy, J.P, Patrone, J.D, Pelz, N.F, Frank, A.O, Vangamudi, B, Sousa-Fagundes, E.M, Rossanese, O.W, Fesik, S.W, Chazin, W.J. | | 登録日 | 2014-08-19 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Diphenylpyrazoles as replication protein a inhibitors.
ACS Med Chem Lett, 6, 2015
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1JKT
 | | TETRAGONAL CRYSTAL FORM OF A CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE | | 分子名称: | DEATH-ASSOCIATED PROTEIN KINASE | | 著者 | Tereshko, V, Teplova, M, Brunzelle, J, Watterson, D.M, Egli, M. | | 登録日 | 2001-07-13 | | 公開日 | 2002-04-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression.
Nat.Struct.Biol., 8, 2001
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5K1B
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1TK9
 | | Crystal Structure of Phosphoheptose isomerase 1 | | 分子名称: | Phosphoheptose isomerase 1 | | 著者 | Rajashankar, K.R, Solorzano, V, Kniewel, R, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-06-08 | | 公開日 | 2004-06-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of two putative phosphoheptose isomerases.
Proteins, 63, 2006
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6VYD
 | | Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Benzyltriethylammonium cation | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Herbst-Gervasoni, C.J, Christianson, D.W. | | 登録日 | 2020-02-26 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases.
Nat Commun, 11, 2020
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1TLB
 | | Yeast coproporphyrinogen oxidase | | 分子名称: | Coproporphyrinogen III oxidase, SULFATE ION | | 著者 | Phillip, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | 登録日 | 2004-06-09 | | 公開日 | 2004-07-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the oxygen-dependent coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
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5KEV
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7B4J
 | | Thermostable omega transaminase PjTA-R6 variant W58M/F86L/R417L engineered for asymmetric synthesis of enantiopure bulky amines | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, SUCCINIC ACID | | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | | 登録日 | 2020-12-02 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
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1T2B
 | | Crystal Structure of cytochrome P450cin complexed with its substrate 1,8-cineole | | 分子名称: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Meharenna, Y.T, Li, H, Hawkes, D.B, Pearson, A.G, De Voss, J, Poulos, T.L. | | 登録日 | 2004-04-20 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam
Biochemistry, 43, 2004
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1T35
 | | CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN YVDD- A PUTATIVE LYSINE DECARBOXYLASE | | 分子名称: | HYPOTHETICAL PROTEIN YVDD, Putative Lysine Decarboxylase, SULFATE ION | | 著者 | Rajashankar, K.R, Kniewel, R, Solorzano, V, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-04-23 | | 公開日 | 2004-05-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Crystal Structure of a Hypothetical Protein Yvdd - Putative Lysine Decarboxylase
To be Published
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3EDZ
 | | Crystal structure of catalytic domain of TACE with hydroxamate inhibitor | | 分子名称: | ADAM 17, CITRIC ACID, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... | | 著者 | Mazzola, R.D, Zhu, Z, Sinning, L, McKittrick, B, Lavey, B, Spitler, J, Kozlowski, J, Neng-Yang, S, Zhou, G, Guo, Z, Orth, P, Madison, V, Sun, J, Lundell, D, Niu, X. | | 登録日 | 2008-09-03 | | 公開日 | 2008-09-23 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket.
Bioorg.Med.Chem.Lett., 18, 2008
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4IC0
 | | Crystal Structure of PAI-1 in Complex with Gallate | | 分子名称: | 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1 | | 著者 | Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D. | | 登録日 | 2012-12-09 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Crystal Structure of PAI-1 in Complex with Gallate
To be Published
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7B4I
 | | Thermostable omega transaminase PjTA-R6 variant W58G engineered for asymmetric synthesis of enantiopure bulky amines | | 分子名称: | Aspartate aminotransferase family protein, PYRIDOXAL-5'-PHOSPHATE, SUCCINIC ACID | | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | | 登録日 | 2020-12-02 | | 公開日 | 2021-09-01 | | 最終更新日 | 2021-09-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Computational Redesign of an omega-Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines.
Acs Catalysis, 11, 2021
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6W1Z
 | | ClpAP Engaged1 State bound to RepA-GFP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | | 登録日 | 2020-03-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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6IGQ
 | | Crystal structure of inactive state of S9 peptidase from Deinococcus radiodurans R1 (PMSF treated) | | 分子名称: | Acyl-peptide hydrolase, putative, GLYCEROL, ... | | 著者 | Yadav, P, Goyal, V.D, Kumar, A, Makde, R.D. | | 登録日 | 2018-09-25 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms.
J.Biol.Chem., 294, 2019
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6W26
 | | Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Imidazole | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, IMIDAZOLE, ... | | 著者 | Herbst-Gervasoni, C.J, Christianson, D.W. | | 登録日 | 2020-03-05 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases.
Nat Commun, 11, 2020
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6W3G
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1JYT
 | | Solution structure of olfactory marker protein from rat | | 分子名称: | Olfactory Marker Protein | | 著者 | Baldisseri, D.M, Margolis, J.W, Weber, D.J, Koo, J.H, Margolis, F.M. | | 登録日 | 2001-09-13 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction.
J.Mol.Biol., 319, 2002
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8A9B
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