5A56
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![BU of 5a56 by Molmil](/molmil-images/mine/5a56) | The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with 1-O-methyl-T-antigen | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ... | 著者 | Gregg, K.J, Suits, M.D.L, Deng, L, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2015-06-16 | 公開日 | 2015-09-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. J.Biol.Chem., 290, 2015
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6ZDQ
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![BU of 6zdq by Molmil](/molmil-images/mine/6zdq) | Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | 分子名称: | RNA, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-15 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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8TYX
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6ZD1
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![BU of 6zd1 by Molmil](/molmil-images/mine/6zd1) | Structure of apo telomerase from Candida Tropicalis | 分子名称: | Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-13 | 公開日 | 2021-04-28 | 最終更新日 | 2021-05-12 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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5A63
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![BU of 5a63 by Molmil](/molmil-images/mine/5a63) | Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Bai, X, Yan, C, Yang, G, Lu, P, Ma, D, Sun, L, Zhou, R, Scheres, S.H.W, Shi, Y. | 登録日 | 2015-06-24 | 公開日 | 2015-08-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | An Atomic Structure of Human Gamma-Secretase Nature, 525, 2015
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6ZD6
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![BU of 6zd6 by Molmil](/molmil-images/mine/6zd6) | Structure of apo telomerase from Candida Tropicalis | 分子名称: | Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-13 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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8TSO
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![BU of 8tso by Molmil](/molmil-images/mine/8tso) | KDL bound, nucleotide-free MsbA in open, outward-facing conformation | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-binding transport protein MsbA, PENTAETHYLENE GLYCOL MONODECYL ETHER | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | 登録日 | 2023-08-11 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8D9Z
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![BU of 8d9z by Molmil](/molmil-images/mine/8d9z) | Crystal structure of Cobra alpha-neurotoxin in complex with Centi-LNX-D09 antibody | 分子名称: | ACETATE ION, Centi-LNX-D09 Fab heavy chain, Centi-LNX-D09 Fab light chain, ... | 著者 | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | 登録日 | 2022-06-12 | 公開日 | 2023-06-14 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Venom protection by antibody from a snakebite hyperimmune subject To Be Published
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7A0S
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![BU of 7a0s by Molmil](/molmil-images/mine/7a0s) | 50S Deinococcus radiodurans ribosome bounded with mycinamicin I | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | 登録日 | 2020-08-10 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida. Nucleic Acids Res., 49, 2021
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5JJK
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![BU of 5jjk by Molmil](/molmil-images/mine/5jjk) | Rho transcription termination factor bound to rA7 and 6 ADP-BeF3 molecules | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Thomsen, N.D, Lawson, M.R, Witkowsky, L.B, Qu, S, Berger, J.M. | 登録日 | 2016-04-24 | 公開日 | 2016-11-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5JVG
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![BU of 5jvg by Molmil](/molmil-images/mine/5jvg) | The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ... | 著者 | Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | 登録日 | 2016-05-11 | 公開日 | 2016-11-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.428 Å) | 主引用文献 | Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding. Proc.Natl.Acad.Sci.USA, 113, 2016
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5LVM
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![BU of 5lvm by Molmil](/molmil-images/mine/5lvm) | Human PDK1 Kinase Domain in Complex with Adenine Bound to the ATP-Binding Site | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENINE, DITHIANE DIOL | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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6YWF
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5CGO
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![BU of 5cgo by Molmil](/molmil-images/mine/5cgo) | Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 13 | 分子名称: | ACPC-13 derivative of Ala-Magainin 2, D-Ala-Magainin 2 | 著者 | Hayouka, Z, Thomas, N.C, Mortenson, D.E, Satyshur, K.A, Weisblum, B, Forest, K.T, Gellman, S.H. | 登録日 | 2015-07-09 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. J.Am.Chem.Soc., 137, 2015
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7ACJ
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![BU of 7acj by Molmil](/molmil-images/mine/7acj) | Structure of translocated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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6QAQ
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![BU of 6qaq by Molmil](/molmil-images/mine/6qaq) | ERK2 mini-fragment binding | 分子名称: | Mitogen-activated protein kinase 1, SULFATE ION, thiophen-3-ylmethylazanium | 著者 | O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. | 登録日 | 2018-12-19 | 公開日 | 2019-03-27 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
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1BL9
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![BU of 1bl9 by Molmil](/molmil-images/mine/1bl9) | CONFORMATIONAL CHANGES OCCURRING UPON REDUCTION IN NITRITE REDUCTASE FROM PSEUDOMONAS AERUGINOSA | 分子名称: | HEME C, HEME D, HYDROXIDE ION, ... | 著者 | Nurizzo, D, Cambillau, C, Tegoni, M. | 登録日 | 1998-07-20 | 公開日 | 1999-04-27 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Conformational changes occurring upon reduction and NO binding in nitrite reductase from Pseudomonas aeruginosa. Biochemistry, 37, 1998
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7ADF
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![BU of 7adf by Molmil](/molmil-images/mine/7adf) | SFX structure of dehaloperoxidase B in the ferric form | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno Chicano, T, Ebrahim, A.E, Axford, D.A, Sherrell, D.A, Sugimoto, H, Tono, K, Owada, S, Worrall, J.W, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2020-09-14 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | SFX structure of dehaloperoxidase B in the ferric form to be published
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7A8Q
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![BU of 7a8q by Molmil](/molmil-images/mine/7a8q) | Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-654 | 分子名称: | 1,2-ETHANEDIOL, 2-cycloheptyl-5-[4-methoxy-3-[[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]methoxy]phenyl]-4,4-dimethyl-pyrazolidin-3-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Singh, A.K, Blaazer, A.R, Zara, L, de Esch, I.J.P, Leurs, R, Brown, D.G. | 登録日 | 2020-08-30 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | hPDE4D2 structure with inhibitor NPD-654 To be published
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8TYY
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7A9V
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![BU of 7a9v by Molmil](/molmil-images/mine/7a9v) | Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-635 | 分子名称: | 1,2-ETHANEDIOL, 1-cycloheptyl-3-[4-methoxy-3-(2-phenylethoxy)phenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Singh, A.K, Blaazer, A.R, Zara, L, de Esch, I.J.P, Leurs, R, Brown, D.G. | 登録日 | 2020-09-02 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | hPDE4D2 structure with inhibitor NPD-635 To be published
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8D78
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7ABZ
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![BU of 7abz by Molmil](/molmil-images/mine/7abz) | Structure of pre-accomodated trans-translation complex on E. coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-09 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7ACP
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![BU of 7acp by Molmil](/molmil-images/mine/7acp) | Serial synchrotron structure of dehaloperoxidase B | 分子名称: | Dehaloperoxidase B, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Moreno Chicano, T, Ebrahim, A.E, Axford, D.A, Sherrell, D.A, Worrall, J.W, Strange, R.W, Owen, R.L, Hough, M.A. | 登録日 | 2020-09-11 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | SFX structure of dehaloperoxidase B in the ferric form to be published
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5LZK
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![BU of 5lzk by Molmil](/molmil-images/mine/5lzk) | Structure of the domain of unknown function DUF1669 from human FAM83B | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Protein FAM83B | 著者 | Pinkas, D.M, Bufton, J.C, Williams, E.P, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2016-09-29 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.575 Å) | 主引用文献 | Structure of the domain of unknown function DUF1669 from human FAM83B To Be Published
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