7A9V

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-635

Summary for 7A9V

Entry DOI	10.2210/pdb7a9v/pdb
Related	6QGP 6QGU 7A28 7A2F 7A8Q
Descriptor	cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
Functional Keywords	phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	171870.93
Authors	Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2020-09-02, release date: 2021-10-06, Last modification date: 2024-01-31)
Primary citation	Singh, A.K.,Brown, D.G. hPDE4D2 structure with inhibitor NPD-635 To be published,
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation