6QGU

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1361

Summary for 6QGU

• Entry DOI: 10.2210/pdb6qgu/pdb
• Related: 6QGP
• Descriptor: Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 82454.22

Authors

Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2019-01-13, release date: 2020-02-05, Last modification date: 2024-01-24)

• Primary citation: Singh, A.K.,Brown, D.G.; Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1361; To be published,

Experimental method

X-RAY DIFFRACTION (1.77 Å)