Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH1143 |
| A | HOH1210 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1143 |
| A | HOH1199 |
| A | HOH1283 |
| A | ASP710 |
| A | HOH1122 |
| A | HOH1125 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1003 |
| Chain | Residue |
| A | GLU768 |
| A | GAI1007 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 1004 |
| Chain | Residue |
| A | GLU765 |
| A | ALA767 |
| A | GLU768 |
| A | HOH1164 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1005 |
| Chain | Residue |
| A | ASP606 |
| A | HOH1211 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GAI A 1006 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | ARG769 |
| A | LEU915 |
| A | HOH1173 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GAI A 1007 |
| Chain | Residue |
| A | GLU696 |
| A | FMT1003 |
| B | TYR686 |
| B | TYR691 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 1008 |
| Chain | Residue |
| A | VAL597 |
| A | LEU598 |
| A | CYS600 |
| A | ARG634 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 1009 |
| Chain | Residue |
| A | VAL610 |
| A | TRP899 |
| A | HOH1225 |
| A | HOH1259 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH1130 |
| B | HOH1228 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | ASP710 |
| B | HOH1130 |
| B | HOH1165 |
| B | HOH1179 |
| B | HOH1200 |
| B | HOH1237 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue GAI B 1003 |
| Chain | Residue |
| B | VAL610 |
| B | HOH1239 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 1004 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | LEU894 |
| B | GLN895 |
| B | GLY896 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 1005 |
| Chain | Residue |
| B | ARG660 |
| B | TYR663 |
| B | ARG664 |
| B | ASN665 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue 863 B 1006 |
| Chain | Residue |
| B | MET785 |
| B | ASN825 |
| B | VAL840 |
| B | GLN874 |
| B | HOH1218 |
| B | HOH1261 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
