6QGU
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1361
Summary for 6QGU
Entry DOI | 10.2210/pdb6qgu/pdb |
Related | 6QGP |
Descriptor | Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (8 entities in total) |
Functional Keywords | parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 82454.22 |
Authors | Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2019-01-13, release date: 2020-02-05, Last modification date: 2024-01-24) |
Primary citation | Singh, A.K.,Brown, D.G. Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1361 To be published, |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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