8CGJ
 
 | | Streptomycin bound to the 30S body | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ... | | 著者 | Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N. | | 登録日 | 2023-02-05 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (1.79 Å) | | 主引用文献 | Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
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6ZB8
 | | Exo-beta-1,3-glucanase from moose rumen microbiome, active site mutant E167Q/E295Q | | 分子名称: | Exo-beta-1,3-glucanase variant E167Q/E295Q, POLYETHYLENE GLYCOL (N=34) | | 著者 | Kalyani, D.C, Reichenbach, T, Aspeborg, H, Divne, C. | | 登録日 | 2020-06-08 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases.
Enzyme.Microb.Technol., 143, 2021
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8CGU
 | | Gentamicin bound to the 30S body | | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | | 著者 | Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N. | | 登録日 | 2023-02-06 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (1.89 Å) | | 主引用文献 | Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
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3NAZ
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6ZCN
 | | Crystal structure of YTHDC1 with m6A | | 分子名称: | N6-METHYLADENOSINE-5'-MONOPHOSPHATE, SULFATE ION, YTHDC1 | | 著者 | Bedi, R.K, Huang, D, Wiedmer, L, Caflisch, A. | | 登録日 | 2020-06-11 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
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3NB8
 | | Crystal structure of oxidized H88Q Synechocystis sp. PCYA | | 分子名称: | 1,2-ETHANEDIOL, BILIVERDINE IX ALPHA, Phycocyanobilin:ferredoxin oxidoreductase | | 著者 | Gae, D.D. | | 登録日 | 2010-06-03 | | 公開日 | 2010-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.
Biochemistry, 49, 2010
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1A71
 | | TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL | | 分子名称: | LIVER ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | | 著者 | Colby, T.D, Bahnson, B.J, Chin, J.K, Klinman, J.P, Goldstein, B.M. | | 登録日 | 1998-03-19 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Biochemistry, 37, 1998
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5KNY
 | | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with (3-((3R,4R)-3-(Guanin-9-yl)-4-((S)-2-hydroxy-2-phosphonoethoxy)pyrrolidin-1-yl)-3-oxopropyl)phosphonic acid | | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid | | 著者 | Eng, W.S, Rejman, D, Keough, D.T, Guddat, L.W. | | 登録日 | 2016-06-28 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with pyrrolidine nucleoside phosphonate
To Be Published
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7KQB
 | | SARS-CoV-2 spike glycoprotein:Fab 5A6 complex I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 5A6 heavy chain, Fab 5A6 light chain, ... | | 著者 | Asarnow, D, Charles, C, Cheng, Y. | | 登録日 | 2020-11-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-06-23 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
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5KOF
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and Acyl Carrier Protein, AcpP | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(prop-2-enoylamino)ethylamino]propyl]amino]butyl] dihydrogen phosphate | | 著者 | Milligan, J.C, Jackson, D.R, Barajas, J.F, Tsai, S.C. | | 登録日 | 2016-06-30 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for interactions between an acyl carrier protein and a ketosynthase.
Nat.Chem.Biol., 15, 2019
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7KZ3
 | | Crystal structure of KabA from Bacillus cereus UW85 in complex with the internal aldimine | | 分子名称: | 1,2-ETHANEDIOL, Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, SODIUM ION | | 著者 | Prasertanan, T, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2020-12-09 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
J.Struct.Biol., 213, 2021
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4ZRO
 | | 2.1 A X-Ray Structure of FIPV-3CLpro bound to covalent inhibitor | | 分子名称: | 3C-like proteinase, Bounded inhibitor of N-(tert-butoxycarbonyl)-L-seryl-L-valyl-N-{(2S)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-leucinamide, DIMETHYL SULFOXIDE | | 著者 | St John, S.E, Mesecar, A.D. | | 登録日 | 2015-05-12 | | 公開日 | 2015-10-14 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.0566 Å) | | 主引用文献 | X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design.
Bioorg.Med.Chem.Lett., 25, 2015
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5A07
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7MQB
 | | Bartonella henselae NrnC bound to pGG. D4 Symmetry | | 分子名称: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQD
 | | Bartonella henselae NrnC complexed with pAGG. D4 symmetry. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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6NOV
 | | A Fab derived from ixekizumab | | 分子名称: | DODECAETHYLENE GLYCOL, Fab Heavy Chain, Fab Light Chain | | 著者 | Durbin, J.D, Clawson, D.K, Lu, F, Tian, Y, Lu, J, Schmitt, M, Atwell, S. | | 登録日 | 2019-01-16 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease.
Mabs, 11, 2019
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5KRP
 | | Frutapin, a lectin from Artocarpus incisa: Cloning, Expressing and Structural Analysis. | | 分子名称: | Frutapin, GLYCEROL | | 著者 | de Sousa, F.D, Coker, A.R, Guan, Y, Guo, J, de Oliveira Monteiro-Moreira, A.C, de Azevedo Moreira, R. | | 登録日 | 2016-07-07 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Frutapin, a lectin fromArtocarpus incisa(breadfruit): cloning, expression and molecular insights.
Biosci. Rep., 37, 2017
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7KZD
 | | Crystal structure of KabA from Bacillus cereus UW85 in complex with the reduced internal aldimine and with bound Glutarate | | 分子名称: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 1,2-ETHANEDIOL, Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme, ... | | 著者 | Prasertanan, T, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2020-12-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
J.Struct.Biol., 213, 2021
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5W0P
 | | Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endolysin,Rhodopsin,S-arrestin | | 著者 | Zhou, X.E, He, Y, de Waal, P.W, Gao, X, Kang, Y, Van Eps, N, Yin, Y, Pal, K, Goswami, D, White, T.A, Barty, A, Latorraca, N.R, Chapman, H.N, Hubbell, W.L, Dror, R.O, Stevens, R.C, Cherezov, V, Gurevich, V.V, Griffin, P.R, Ernst, O.P, Melcher, K, Xu, H.E. | | 登録日 | 2017-05-31 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.013 Å) | | 主引用文献 | Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Cell, 170, 2017
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7MQC
 | | Bartonella henselae NrnC bound to pGG. C1 reconstruction. | | 分子名称: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPM
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5HVQ
 | | Alternative model of the MAGE-G1 NSE-1 complex | | 分子名称: | Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ZINC ION | | 著者 | Newman, J.A, Cooper, C.D.O, Roos, A.K, Aitkenhead, H, Oppermann, U.C.T, Cho, H.J, Osman, R, Gileadi, O. | | 登録日 | 2016-01-28 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | | 主引用文献 | Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
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7MPN
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6NSP
 | | TRK-A IN COMPLEX WITH LIGAND 9 | | 分子名称: | High affinity nerve growth factor receptor, N-(8-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-(3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl)acetamide | | 著者 | Subramanian, G, Brown, D.G. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A ( hTrkA) Inhibitors.
Acs Chem.Biol., 14, 2019
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4U92
 | | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad | | 分子名称: | BARIUM ION, DNA (5'-D(*CP*CP*AP*KP*GP*CP*GP*TP*GP*G)-3'), MAGNESIUM ION | | 著者 | Paukstelis, P.J, Zhang, D, Huang, T, Lukeman, P. | | 登録日 | 2014-08-05 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a DNA/Ba2+ G-quadruplex containing a water-mediated C-tetrad.
Nucleic Acids Res., 42, 2014
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