8EVD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8evd by Molmil](/molmil-images/mine/8evd) | |
7QT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qt6 by Molmil](/molmil-images/mine/7qt6) | Room temperature In-situ SARS-CoV-2 MPRO with bound Z1367324110 | 分子名称: | 1-methyl-3,4-dihydro-2~{H}-quinoline-7-sulfonamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE | 著者 | Horrell, S, Gildae, R.J, Axford, D, Owen, C.D, Lukacik, P, Strain-Damerell, C, Owen, R.L, Walsh, M.A. | 登録日 | 2022-01-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | xia2.multiplex: a multi-crystal data-analysis pipeline. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7QT5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qt5 by Molmil](/molmil-images/mine/7qt5) | Room temperature In-situ SARS-CoV-2 MPRO with bound Z31792168 | 分子名称: | 2-cyclohexyl-~{N}-pyridin-3-yl-ethanamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE | 著者 | Horrell, S, Gildae, R.J, Axford, D, Owen, C.D, Lukacik, P, Strain-Damerell, C, Owen, R.L, Walsh, M.A. | 登録日 | 2022-01-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | xia2.multiplex: a multi-crystal data-analysis pipeline. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7QT7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qt7 by Molmil](/molmil-images/mine/7qt7) | Room temperature In-situ SARS-CoV-2 MPRO with bound Z4439011520 | 分子名称: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-(5-tert-butyl-1,2-oxazol-3-yl)-N-[(1R)-2-[(4-methoxy-2-methylphenyl)amino]-2-oxo-1-(pyridin-3-yl)ethyl]propanamide | 著者 | Horrell, S, Gildae, R.J, Axford, D, Owen, C.D, Lukacik, P, Strain-Damerell, C, Owen, R.L, Walsh, M.A. | 登録日 | 2022-01-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | xia2.multiplex: a multi-crystal data-analysis pipeline. Acta Crystallogr D Struct Biol, 78, 2022
|
|
6MTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mtq by Molmil](/molmil-images/mine/6mtq) | Crystal structure of VRC42.N1 Fab in complex with T117-F MPER scaffold | 分子名称: | Antibody VRC42.N1 Fab heavy chain, Antibody VRC42.N1 Fab light chain, VRC42 epitope T117-F scaffold | 著者 | Kwon, Y.D, Law, W.H, Veradi, R, Doria-Rose, N.A, Kwong, P.D. | 登録日 | 2018-10-21 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity, 50, 2019
|
|
8C67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c67 by Molmil](/molmil-images/mine/8c67) | Crystal structure of Ab25 Fab | 分子名称: | antibody 25 heavy chain, antibody 25 light chain | 著者 | Nyblom, M, Izadi, A, Tang, D, Bahnan, W, Happonen, L, Malmstroem, J, Shannon, O, Malmstroem, L, Nordenfelt, P. | 登録日 | 2023-01-11 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Engineering of IgG1 hinge to the flexible IgG3 hinge enhances immune defense against streptococci To Be Published
|
|
8FWA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwa by Molmil](/molmil-images/mine/8fwa) | Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography | 分子名称: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ... | 著者 | Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A. | 登録日 | 2023-01-20 | 公開日 | 2023-06-28 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme. Lab Chip, 23, 2023
|
|
8HKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hke by Molmil](/molmil-images/mine/8hke) | dsRNA transporter | 分子名称: | RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-25 | 公開日 | 2023-11-29 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1. Nat.Struct.Mol.Biol., 31, 2024
|
|
8TC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tc9 by Molmil](/molmil-images/mine/8tc9) | Human asparaginyl-tRNA synthetase bound to OSM-S-106 | 分子名称: | Asparagine--tRNA ligase, cytoplasmic, GLYCEROL, ... | 著者 | Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | 登録日 | 2023-06-30 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
|
|
8DFR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dfr by Molmil](/molmil-images/mine/8dfr) | REFINED CRYSTAL STRUCTURES OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE. 3 ANGSTROMS APO-ENZYME AND 1.7 ANGSTROMS NADPH HOLO-ENZYME COMPLEX | 分子名称: | CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Matthews, D.A, Oatley, S.J, Burridge, J, Kaufman, B.T, Xuong, N.-H, Kraut, J. | 登録日 | 1989-05-30 | 公開日 | 1989-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Refined Crystal Structures of Chicken Liver Dihydrofolate Reductase. 3 Angstroms Apo-Enzyme and 1.7 Angstroms Nadph Holo-Enzyme Complex To be Published
|
|
8FE4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fe4 by Molmil](/molmil-images/mine/8fe4) | Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody | 分子名称: | Envelope protein E, prM protein, prM13 Fab Heavy Chain, ... | 著者 | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | 登録日 | 2022-12-05 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8FE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fe3 by Molmil](/molmil-images/mine/8fe3) | Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody | 分子名称: | Envelope protein E, prM protein, prM12 Fab Heavy Chain, ... | 著者 | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | 登録日 | 2022-12-05 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (10.2 Å) | 主引用文献 | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6MUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6muh by Molmil](/molmil-images/mine/6muh) | Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation crystallography | 分子名称: | Fluoroacetate dehalogenase | 著者 | Finke, A.D, Wierman, J.L, Pare-Labrosse, O, Sarrachini, A, Besaw, J, Mehrabi, P, Gruner, S.M, Miller, R.J.D. | 登録日 | 2018-10-23 | 公開日 | 2019-03-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fixed-target serial oscillation crystallography at room temperature. IUCrJ, 6, 2019
|
|
8FDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fdp by Molmil](/molmil-images/mine/8fdp) | |
8FDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fdr by Molmil](/molmil-images/mine/8fdr) | Structure of a dodecamer complex: 5'-CGCGAAAAGCCG-3-DB1476 | 分子名称: | 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*TP*TP*TP*CP*GP*CP*G)-3'), ... | 著者 | Ogbonna, E, Wilson, W.D. | 登録日 | 2022-12-04 | 公開日 | 2023-02-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences. Acs Bio Med Chem Au, 3, 2023
|
|
6N1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n1z by Molmil](/molmil-images/mine/6n1z) | |
8DB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8db5 by Molmil](/molmil-images/mine/8db5) | Crystal structure of the GDP-D-glycero-4-keto-d-lyxo-heptose-3,5-epimerase from Campylobacter jejuni, serotype HS:15 | 分子名称: | CHLORIDE ION, GDP-D-glycero-4-keto-d-lyxo-heptose-3,5-epimerase, GUANOSINE-5'-DIPHOSPHATE | 著者 | Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M. | 登録日 | 2022-06-14 | 公開日 | 2022-06-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni . Biochemistry, 61, 2022
|
|
6PHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6phl by Molmil](/molmil-images/mine/6phl) | |
6PK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pk8 by Molmil](/molmil-images/mine/6pk8) | Antibody scFv-M204 dimeric state | 分子名称: | SULFATE ION, scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-06-28 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
|
|
7A2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7a2b by Molmil](/molmil-images/mine/7a2b) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q207D | 分子名称: | MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Bischoff, D, Hermann, J, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-08-17 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
|
|
6PB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pb1 by Molmil](/molmil-images/mine/6pb1) | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 | 分子名称: | CHOLESTEROL, Corticotropin-releasing factor receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Shen, Q, Zhao, L.-H, Mao, C, Zhou, X.E, Shen, D.-D, de Waal, P.W, Bi, P, Li, C, Jiang, Y, Wang, M.-W, Sexton, P.M, Wootten, D, Melcher, K, Zhang, Y, Xu, H.E. | 登録日 | 2019-06-12 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. Mol.Cell, 77, 2020
|
|
7ACF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7acf by Molmil](/molmil-images/mine/7acf) | |
6NKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nkh by Molmil](/molmil-images/mine/6nkh) | |
7QOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qoc by Molmil](/molmil-images/mine/7qoc) | |
8FUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fur by Molmil](/molmil-images/mine/8fur) | Crystal structure of human IDO1 with compound 11 | 分子名称: | Indoleamine 2,3-dioxygenase 1, N-(4-methylphenyl)-N'-[(1P,2'P)-4-propoxy-5-propyl-2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]urea | 著者 | Critton, D.A, Lewis, H.A. | 登録日 | 2023-01-18 | 公開日 | 2023-04-26 | 最終更新日 | 2023-05-03 | 実験手法 | X-RAY DIFFRACTION (2.285 Å) | 主引用文献 | Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1. Bioorg.Med.Chem.Lett., 88, 2023
|
|