9ICD
 
 | | CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES | | 分子名称: | ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Hurley, J.H, Dean, A.M, Koshland Jr, D.E, Stroud, R.M. | | 登録日 | 1991-07-29 | | 公開日 | 1991-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes.
Biochemistry, 30, 1991
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4TTL
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8THX
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9B7C
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8WNU
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8W68
 | | Crystal structure of Q9PR55 at pH 6.0 (use NMR model) | | 分子名称: | Uncharacterized protein UU089.1 | | 著者 | Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. | | 登録日 | 2023-08-28 | | 公開日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot.
J.Biol.Chem., 300, 2023
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9AUC
 | | Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin gene-related peptide 1, ... | | 著者 | Cao, J, Belousoff, M.J, Wootten, D.L, Sexton, P.M. | | 登録日 | 2024-02-28 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein.
Biochemistry, 63, 2024
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4TRQ
 | | Crystal structure of Sac3/Thp1/Sem1 | | 分子名称: | 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... | | 著者 | Hellerschmied, D, Schneider, S, Kohler, A, Clausen, T. | | 登録日 | 2014-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.
Cell, 162, 2015
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8WO4
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8VEI
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8W1V
 | | The beta2 adrenergic receptor bound to a bitopic ligand | | 分子名称: | (2S)-1-[(3-{1-[4-(4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butyl]-1H-1,2,3-triazol-4-yl}propyl)amino]-3-(2-propylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Endolysin, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Gaiser, B, Danielsen, M, Xu, X, Jorgensen, K, Fronik, P, Marcher-Rorsted, E, Wrobe, T, Hirata, K, Liu, X, Mathiesen, J, Pedersen, D. | | 登録日 | 2024-02-19 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Bitopic Ligands Support the Presence of a Metastable Binding Site at the beta 2 Adrenergic Receptor.
J.Med.Chem., 67, 2024
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4RUF
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9EZZ
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8THY
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8UC7
 | | HCN1 complex with propofol | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,6-BIS(1-METHYLETHYL)PHENOL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Kim, E.D, Nimigean, C.M. | | 登録日 | 2023-09-25 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants
Nature, 2024
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9BC6
 | | HCN1 M305L with propofol | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,6-BIS(1-METHYLETHYL)PHENOL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Kim, E.D, Nimigean, C.M. | | 登録日 | 2024-04-07 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants
Nature, 2024
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9BC7
 | | HCN1 M305L holo | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Kim, E.D, Nimigean, C.M. | | 登録日 | 2024-04-08 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants
Nature, 2024
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4RN5
 | | B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site | | 分子名称: | ACETATE ION, GLYCEROL, Neuropilin-1, ... | | 著者 | Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. | | 登録日 | 2014-10-23 | | 公開日 | 2015-10-28 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Conserved water molecules in a ligand-binding site of neuropilin-1
To be Published
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4S0I
 | | Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79S, and 123A mutant | | 分子名称: | Threonine--tRNA ligase | | 著者 | Pearson, A.D, Mills, J.H, Song, Y, Nasertorabi, F, Han, G.W, Baker, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2014-12-31 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Transition states. Trapping a transition state in a computationally designed protein bottle.
Science, 347, 2015
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113D
 | | THE STRUCTURE OF GUANOSINE-THYMIDINE MISMATCHES IN B-DNA AT 2.5 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*TP*GP*CP*G)-3') | | 著者 | Hunter, W.N, Brown, T, Kneale, G, Anand, N.N, Rabinovich, D, Kennard, O. | | 登録日 | 1993-01-04 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of guanosine-thymidine mismatches in B-DNA at 2.5-A resolution.
J.Biol.Chem., 262, 1987
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4RO9
 | | 2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae | | 分子名称: | GLYCEROL, Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
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4RWI
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12CA
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138L
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139L
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