12CA

ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121

Summary for 12CA

DescriptorCARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (4 entities in total)
Functional Keywordslyase(oxo-acid)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P00918
Total number of polymer chains1
Total molecular weight29527.01
Authors
Nair, S.K.,Christianson, D.W. (deposition date: 1991-10-01, release date: 1992-10-15, Last modification date: 2017-11-29)
Primary citation
Nair, S.K.,Calderone, T.L.,Christianson, D.W.,Fierke, C.A.
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.
J.Biol.Chem., 266:17320-17325, 1991
PubMed: 1910042 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers170.8%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution