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PDB: 53526 件

5EPW
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C-Terminal Domain Of Human Coronavirus Nl63 Nucleocapsid Protein
分子名称: Nucleoprotein
著者Szelazek, B, Kabala, W, Kus, K, Zdzalik, M, Golik, P, Florek, D, Burmistrz, M, Pyrc, K, Dubin, G.
登録日2015-11-12
公開日2017-02-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Characterization of Human Coronavirus NL63 N Protein.
J. Virol., 91, 2017
6DMJ
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A multiconformer ligand model of inhibitor 53W bound to CREB binding protein bromodomain
分子名称: 5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[2-(4-methoxyphenyl)ethyl]-1-[2-(morpholin-4-yl)ethyl]-1H-benzimidazole, Bromodomain-containing protein 4
著者Hudson, B.M, van Zundert, G, Keedy, D.A, Fonseca, R, Heliou, A, Suresh, P, Borrelli, K, Day, T, Fraser, J.S, van den Bedem, H.
登録日2018-06-05
公開日2018-12-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps.
J. Med. Chem., 61, 2018
5EI3
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Co-crystal structure of eIF4E with nucleotide mimetic inhibitor.
分子名称: Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation initiation factor 4E, SULFATE ION, ...
著者Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M.
登録日2015-10-29
公開日2016-09-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.
Eur.J.Med.Chem., 124, 2016
5EEK
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trichostatin A
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-23
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
5EEF
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 in complex with trichostatin A
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, HDAC6, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-22
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
4LOI
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Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p]
分子名称: 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, PHOSPHATE ION, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2013-07-12
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
6D7H
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CTX-M-14 Apoenzyme
分子名称: Beta-lactamase, PHOSPHATE ION, POTASSIUM ION
著者Kemp, M, Nichols, D, Chen, Y.
登録日2018-04-24
公開日2019-07-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献The Role of Asp-Asp Short Hydrogen Bond in Maintaining Active Site Integrity of CTX-M Beta-Lactamase
To be Published
5EJ0
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The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ...
著者Singh, K, Gittis, A.G, Gitti, R.K, Ostazesky, S.A, Su, H.P, Garboczi, D.N.
登録日2015-10-30
公開日2016-03-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-Glucose.
J.Virol., 90, 2016
7WZM
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Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis in complex with Oleic acid
分子名称: OLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450
著者Kim, V.C, Kim, D.G, Lee, S.G, Lee, G.H, Lee, S.A, Kang, L.W.
登録日2022-02-18
公開日2023-02-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis in complex with Oleic acid
To Be Published
5EEN
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat
分子名称: Belinostat, CHLORIDE ION, Hdac6 protein, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-23
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.861 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
2FQA
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Violacin A
分子名称: violacin 1
著者Ireland, D.C, Craik, D.J, Daly, N.L.
登録日2006-01-17
公開日2006-01-31
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Discovery and Characterization of a Linear Cyclotide from Viola odorata: Implications for the Processing of Circular Proteins
J.Mol.Biol., 357, 2006
5EFK
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (Y745F mutant) in complex with alpha tubulin K40 tripeptide substrate
分子名称: 1,2-ETHANEDIOL, 7-AMINO-4-METHYL-CHROMEN-2-ONE, DI(HYDROXYETHYL)ETHER, ...
著者Hai, Y, Christianson, D.W.
登録日2015-10-23
公開日2016-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Nat.Chem.Biol., 12, 2016
2FWT
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Crystal structure of DHC purified from Rhodobacter sphaeroides
分子名称: DHC, diheme cytochrome c, HEME C
著者Leys, D.
登録日2006-02-03
公開日2006-05-23
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Studies on DHC, the Diheme Cytochrome c from Rhodobacter sphaeroides, and Its Interaction with SHP, the sphaeroides Heme Protein
Biochemistry, 45, 2006
4W88
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Crystal structure of XEG5A, a GH5 xyloglucan-specific endo-beta-1,4-glucanase from ruminal metagenomic library, in complex with a xyloglucan oligosaccharide and TRIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, Xyloglucan-specific endo-beta-1,4-glucanase, ...
著者Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
6DFT
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BU of 6dft by Molmil
Trypanosoma brucei deoxyhypusine synthase
分子名称: Deoxyhypusine synthase, Deoxyhypusine synthase regulatory subunit, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Tomchick, D.R, Phillips, M.A, Afanador, G.A.
登録日2018-05-15
公開日2018-08-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs.
Structure, 26, 2018
5EK5
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BU of 5ek5 by Molmil
STRUCTURAL CHARACTERIZATION OF IRMA FROM ESCHERICHIA COLI
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ...
著者Heras, B, Moriel, D.G, Paxman, J.J, Schembri, M.A.
登録日2015-11-03
公開日2016-03-09
最終更新日2016-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein.
Mbio, 7, 2016
4M6U
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P. putida mandelate racemase co-crystallized with tartronic acid
分子名称: MAGNESIUM ION, Mandelate racemase, TARTRONATE
著者Lietzan, A.D, St.Maurice, M.
登録日2013-08-11
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode.
Biochemistry, 53, 2014
5EE7
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Crystal structure of the human glucagon receptor (GCGR) in complex with the antagonist MK-0893
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, 3-[[4-[(1~{S})-1-[3-[3,5-bis(chloranyl)phenyl]-5-(6-methoxynaphthalen-2-yl)pyrazol-1-yl]ethyl]phenyl]carbonylamino]propanoic acid, Glucagon receptor,Endolysin,Glucagon receptor, ...
著者Jazayeri, A, Dore, A.S, Lamb, D, Krishnamurthy, H, Southall, S.M, Baig, A.H, Bortolato, A, Koglin, M, Robertson, N.J, Errey, J.C, Andrews, S.P, Brown, A.J.H, Cooke, R.M, Weir, M, Marshall, F.H.
登録日2015-10-22
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Extra-helical binding site of a glucagon receptor antagonist.
Nature, 533, 2016
8TVB
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Ghanaian virus fusion glycoprotein (GhV F)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-17
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVI
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Langya Virus G glycoprotein (LayV G) with stabilizing mutations
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment glycoprotein G, ZINC ION
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-08-18
公開日2024-05-01
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
4W8B
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Crystal structure of XEG5B, a GH5 xyloglucan-specific beta-1,4-glucanase from ruminal metagenomic library, in complex with XXLG
分子名称: Exo-xyloglucanase, GLYCEROL, SULFATE ION, ...
著者Santos, C.R, Cordeiro, R.L, Wong, D.W.S, Murakami, M.T.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Basis for Xyloglucan Specificity and alpha-d-Xylp(1 6)-d-Glcp Recognition at the -1 Subsite within the GH5 Family.
Biochemistry, 54, 2015
2FOT
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Crystal structure of the complex between calmodulin and alphaII-spectrin
分子名称: CALCIUM ION, Calmodulin, alpha-II spectrin Spectrin
著者Simonovic, M, Zhang, Z, Cianci, C.D, Steitz, T.A, Morrow, J.S.
登録日2006-01-13
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
4LOL
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Crystal structure of mSting in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2013-07-12
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA.
Cell(Cambridge,Mass.), 154, 2013
8TVH
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Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ...
著者Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-08-18
公開日2024-05-08
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
5EMV
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Crystal structure of the palmitoylated human TEAD2 transcription factor
分子名称: Transcriptional enhancer factor TEF-4
著者Noland, C.L, Gierke, S, Schnier, P.D, Murray, J, Sandoval, W.N, Sagolla, M, Dey, A, Hannoush, R.N, Fairbrother, W.J, Cunningham, C.N.
登録日2015-11-06
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling.
Structure, 24, 2016

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件を2024-10-09に公開中

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