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PDB: 263 results

1MFE
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BU of 1mfe by Molmil
RECOGNITION OF A CELL-SURFACE OLIGO-SACCHARIDE OF PATHOGENIC SALMONELLA BY AN ANTIBODY FAB FRAGMENT
Descriptor: IGG1-LAMBDA SE155-4 FAB (HEAVY CHAIN), IGG1-LAMBDA SE155-4 FAB (LIGHT CHAIN), alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose
Authors:Cygler, M.
Deposit date:1993-10-25
Release date:1994-01-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
Science, 253, 1991
2Q1F
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Crystal structure of chondroitin sulfate lyase abc from bacteroides thetaiotaomicron wal2926
Descriptor: CALCIUM ION, Chondroitinase, PHOSPHATE ION
Authors:Shaya, D, Cygler, M.
Deposit date:2007-05-24
Release date:2008-01-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid.
Glycobiology, 18, 2008
6MCQ
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BU of 6mcq by Molmil
L. pneumophila effector kinase LegK7 in complex with human MOB1A
Descriptor: DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ...
Authors:Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M.
Deposit date:2018-09-01
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
7LSV
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BU of 7lsv by Molmil
Non-kinase domain of Legionella effector protein kinase LegK2
Descriptor: Calmodulin-dependent protein kinase, MALONATE ION, SODIUM ION
Authors:Beyrakhova, K.A, van Straaten, K, Cygler, M.
Deposit date:2021-02-18
Release date:2022-01-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Non-kinase domain of Legionella effector protein kinase LegK2
To Be Published
3BFP
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BU of 3bfp by Molmil
Crystal Structure of apo-PglD from Campylobacter jejuni
Descriptor: Acetyltransferase, CITRATE ANION
Authors:Rangarajan, E.S, Watson, D.C, Leclerc, S, Proteau, A, Cygler, M, Matte, A, Young, N.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2007-11-22
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Active Site Residues of PglD, an N-Acetyltransferase from the Bacillosamine Synthetic Pathway Required for N-Glycan Synthesis in Campylobacter jejuni.
Biochemistry, 47, 2008
2AHV
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BU of 2ahv by Molmil
Crystal Structure of Acyl-CoA transferase from E. coli O157:H7 (YdiF)-thioester complex with CoA- 1
Descriptor: COENZYME A, putative enzyme YdiF
Authors:Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2005-07-28
Release date:2005-11-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.
J.Biol.Chem., 280, 2005
5WLW
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BU of 5wlw by Molmil
Crystal Structure of the Human Mitochondrial Cysteine Desulfurase with active Cysteine Loop within ISCU1 active site, coordinating Zn ion. Complexed with human ISD11 and E. coli ACP1 at 3.3A.
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2017-07-27
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.317 Å)
Cite:Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
5WGB
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BU of 5wgb by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2017-07-13
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
3BE6
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BU of 3be6 by Molmil
Crystal structure of FitE (crystal form 2), a group III periplasmic siderophore binding protein
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2007-11-16
Release date:2008-10-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Trapping open and closed forms of FitE-A group III periplasmic binding protein.
Proteins, 75, 2008
4MU6
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BU of 4mu6 by Molmil
Crystal Structure of the N-terminal domain of Effector Protein LegC3 from Legionella pneumophila
Descriptor: Kinectin 1 (Kinesin receptor)
Authors:Yao, D, Cherney, M, Cygler, M.
Deposit date:2013-09-20
Release date:2013-12-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.082 Å)
Cite:Structure of the N-terminal domain of the effector protein LegC3 from Legionella pneumophila.
Acta Crystallogr.,Sect.D, 70, 2014
4WL1
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BU of 4wl1 by Molmil
Structure of WzzE Polysaccharide Co-polymerase
Descriptor: Lipopolysaccharide biosynthesis protein WzzE
Authors:Kalynych, S, Cherney, M, Cygler, M.
Deposit date:2014-10-05
Release date:2014-10-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (5.989 Å)
Cite:Quaternary structure of WzzB and WzzE polysaccharide copolymerases.
Protein Sci., 24, 2015
8EP4
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BU of 8ep4 by Molmil
Structure of Bacple_01703
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ...
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2022-10-05
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
8EW1
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BU of 8ew1 by Molmil
Structure of Bacple_01703-E145L
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2022-10-21
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
4LRZ
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BU of 4lrz by Molmil
Crystal Structure of the E.coli DhaR(N)-DhaL complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PTS-dependent dihydroxyacetone kinase operon regulatory protein, ...
Authors:Shi, R, McDonald, L, Cygler, M, Ekiel, I.
Deposit date:2013-07-21
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR.
Structure, 22, 2014
8SWI
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BU of 8swi by Molmil
Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide
Descriptor: Eukaryotic huntingtin interacting protein B, Histone H3 peptided, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Xu, C, Chung, I.Y.W, Cygler, M.
Deposit date:2023-05-18
Release date:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.
Mbio, 14, 2023
7TZK
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BU of 7tzk by Molmil
EPS8 SH3 Domain with NleH1 PxxDY Motif
Descriptor: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog
Authors:Grishin, A.M, Cygler, M.
Deposit date:2022-02-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli
Proc.Natl.Acad.Sci.USA, 119, 2022
8SR6
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BU of 8sr6 by Molmil
Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Eukaryotic huntingtin interacting protein B, ...
Authors:Xu, C, Chung, I.Y.W, Cygler, M.
Deposit date:2023-05-05
Release date:2024-03-13
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.
Mbio, 14, 2023
7PCK
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BU of 7pck by Molmil
CRYSTAL STRUCTURE OF WILD TYPE HUMAN PROCATHEPSIN K
Descriptor: PROTEIN (PROCATHEPSIN K)
Authors:Sivaraman, J, Lalumiere, M, Menard, R, Cygler, M.
Deposit date:1998-10-21
Release date:1999-10-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of wild-type human procathepsin K.
Protein Sci., 8, 1999
7UPS
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BU of 7ups by Molmil
Structural study of Legionella pneumophila effector DotY (Lpg0294)
Descriptor: 1,2-ETHANEDIOL, DotY (Lpg0294)
Authors:Chung, I.Y.W, Cygler, M.
Deposit date:2022-04-16
Release date:2022-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system.
Acta Crystallogr.,Sect.F, 78, 2022
5FIA
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BU of 5fia by Molmil
Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LpiR1
Authors:Beyrakhova, K, van Straaten, K, Cygler, M.
Deposit date:2015-12-22
Release date:2016-01-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
J.Biol.Chem., 291, 2016
7SNO
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BU of 7sno by Molmil
Structure of Bacple_01701(H214N), a 6-O-galactose porphyran sulfatase
Descriptor: 1,2-ETHANEDIOL, 6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose, Arylsulfatase, ...
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2021-10-28
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
7SNJ
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BU of 7snj by Molmil
Structure of Bacple_01701, a 6-O-galactose porphyran sulfatase
Descriptor: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Arylsulfatase, ...
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2021-10-28
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
7SNK
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BU of 7snk by Molmil
Structure of Bacple_01702, a GH29 family glycoside hydrolase
Descriptor: Alpha-L-fucosidase, PHOSPHATE ION, POTASSIUM ION
Authors:Ulaganathan, T, Cygler, M.
Deposit date:2021-10-28
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations
Biorxiv, 2023
6P0X
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BU of 6p0x by Molmil
Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACRYLIC ACID, GLYCEROL, ...
Authors:Xu, C, Boniecki, M, Cygler, M.
Deposit date:2019-05-17
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2
To Be Published
1HQV
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BU of 1hqv by Molmil
STRUCTURE OF APOPTOSIS-LINKED PROTEIN ALG-2
Descriptor: CALCIUM ION, PROGRAMMED CELL DEATH PROTEIN 6
Authors:Jia, J, Tarabykina, S, Hansen, C, Berchtold, M, Cygler, M.
Deposit date:2000-12-19
Release date:2001-05-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of apoptosis-linked protein ALG-2: insights into Ca2+-induced changes in penta-EF-hand proteins.
Structure, 9, 2001

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