2QFD
 
 | | Crystal structure of the regulatory domain of human RIG-I with bound Hg | | Descriptor: | MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58 | | Authors: | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | | Deposit date: | 2007-06-27 | | Release date: | 2008-02-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
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2QFB
 | | Crystal structure of the regulatory domain of human RIG-I with bound Zn | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, ZINC ION | | Authors: | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | | Deposit date: | 2007-06-27 | | Release date: | 2008-02-12 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
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3OCI
 | | Crystal structure of TBP (TATA box binding protein) | | Descriptor: | 1,2-ETHANEDIOL, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | | Authors: | Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P. | | Deposit date: | 2010-08-10 | | Release date: | 2011-07-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.899 Å) | | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
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3EIK
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3K1K
 | | Green fluorescent protein bound to enhancer nanobody | | Descriptor: | Enhancer, Green Fluorescent Protein | | Authors: | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | | Deposit date: | 2009-09-28 | | Release date: | 2009-12-08 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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5GNB
 | | Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 2.3 angstrom, native-SAD phasing) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Guan, H, Wojdyla, J.A, Wang, M, Cui, S. | | Deposit date: | 2016-07-20 | | Release date: | 2017-06-07 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
Nat Commun, 8, 2017
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5GRB
 | | Crystal structure of 2C helicase from enterovirus 71 (EV71) bound with ATPgammaS | | Descriptor: | EV71 2C ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION | | Authors: | Guan, H.X, Tian, J, Qin, B, Wojdyla, J, Wang, M.T, Cui, S. | | Deposit date: | 2016-08-09 | | Release date: | 2017-05-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.803 Å) | | Cite: | Crystal structure of 2C helicase from enterovirus 71
SCI ADV, 3, 2017
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5YBH
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8YG1
 | | The Dimer Structure of DSR2 alone | | Descriptor: | SIR2-like domain-containing protein | | Authors: | Gao, X, Zhu, H, Cui, S. | | Deposit date: | 2024-02-26 | | Release date: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Activation of the bacterial defense-associated sirtuin system.
Commun Biol, 8, 2025
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8YGA
 | | The tetramer Structure of DSR2 alone | | Descriptor: | SIR2-like domain-containing protein | | Authors: | Gao, X, Zhu, H, Cui, S. | | Deposit date: | 2024-02-26 | | Release date: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (4.53 Å) | | Cite: | Activation of the bacterial defense-associated sirtuin system.
Commun Biol, 8, 2025
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8YGM
 | | The cryo-EM Structure of SPR | | Descriptor: | SPR | | Authors: | Gao, X, Zhu, H, Cui, S. | | Deposit date: | 2024-02-26 | | Release date: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Activation of the bacterial defense-associated sirtuin system.
Commun Biol, 8, 2025
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8YGN
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8YGO
 | | The complex by DSR2-CTD-SPR with NAD | | Descriptor: | SIR2-like domain-containing protein, SPR | | Authors: | Gao, X, Zhu, H, Cui, S. | | Deposit date: | 2024-02-26 | | Release date: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Activation of the bacterial defense-associated sirtuin system.
Commun Biol, 8, 2025
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8YGP
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8YGC
 | | The Dimer Structure of DSR2-SPR | | Descriptor: | SIR2-like domain-containing protein, SPR | | Authors: | Gao, X, Zhu, H, Cui, S. | | Deposit date: | 2024-02-26 | | Release date: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Activation of the bacterial defense-associated sirtuin system.
Commun Biol, 8, 2025
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8YGK
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8YGF
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8YQQ
 | | Structure of HKU1B RBD with TMPRSS2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, Transmembrane protease serine 2 | | Authors: | Gao, X, Cui, S, Ding, W, Zhu, K, Shang, K, Zhu, H. | | Deposit date: | 2024-03-19 | | Release date: | 2024-08-28 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.95 Å) | | Cite: | Structural basis for the interaction between human coronavirus HKU1 spike receptor binding domain and its receptor TMPRSS2.
Cell Discov, 10, 2024
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8YOY
 | | Structure of HKU1A RBD with TMPRSS2 | | Descriptor: | Spike protein S1, Transmembrane protease serine 2 | | Authors: | Gao, X, Cui, S, Ding, W, Shang, K, Zhu, H, Zhu, K. | | Deposit date: | 2024-03-14 | | Release date: | 2024-08-28 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structural basis for the interaction between human coronavirus HKU1 spike receptor binding domain and its receptor TMPRSS2.
Cell Discov, 10, 2024
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6JIJ
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8K88
 | | Structure of procaryotic Ago | | Descriptor: | DNA (41-mer), DNA/RNA (21-mer), MAGNESIUM ION, ... | | Authors: | Gao, X, Sun, D, Cui, S, Wang, Y. | | Deposit date: | 2023-07-29 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Nucleic acid-induced NADase activation of a short Sir2-associated prokaryotic Argonaute system.
Cell Rep, 43, 2024
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8K87
 | | Dimer structure of procaryotic Ago | | Descriptor: | DNA (41-mer), MAGNESIUM ION, Piwi domain protein, ... | | Authors: | Gao, X, Sun, D, Cui, S, Wang, Y. | | Deposit date: | 2023-07-29 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Nucleic acid-induced NADase activation of a short Sir2-associated prokaryotic Argonaute system.
Cell Rep, 43, 2024
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8K9G
 | | Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | | Descriptor: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | | Deposit date: | 2023-08-01 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute.
Nature, 625, 2024
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2W4R
 | | Crystal structure of the regulatory domain of human LGP2 | | Descriptor: | MERCURY (II) ION, PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, SULFATE ION | | Authors: | Pippig, D.A, Hellmuth, J.C, Cui, S, Kirchhofer, A, Lammens, K, Lammens, A, Schmidt, A, Rothenfusser, S, Hopfner, K.P. | | Deposit date: | 2008-12-01 | | Release date: | 2009-02-24 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
Nucleic Acids Res., 37, 2009
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5H7Y
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