7A9X
| Structure of yeast Rmd9p in complex with 16nt target RNA | 分子名称: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | 著者 | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | 登録日 | 2020-09-02 | 公開日 | 2021-04-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
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7B3D
| Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with AMP at position -4 (structure 3) | 分子名称: | RNA (5'-R(P*CP*UP*AP*CP*GP*CP*AP*GP*UP*G)-3'), RNA (5'-R(P*UP*GP*CP*AP*CP*UP*GP*CP*GP*UP*AP*G)-3'), SARS-CoV-2 RNA-dependent RNA polymerase nsp12, ... | 著者 | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | 登録日 | 2020-11-30 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
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7B3B
| Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) | 分子名称: | DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... | 著者 | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | 登録日 | 2020-11-30 | 公開日 | 2020-12-23 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
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7B3C
| Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -4 (structure 2) | 分子名称: | DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*A)-D(P*(RMP))-R(P*GP*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... | 著者 | Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. | 登録日 | 2020-11-30 | 公開日 | 2020-12-23 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
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7B0Y
| Structure of a transcribing RNA polymerase II-U1 snRNP complex | 分子名称: | 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... | 著者 | Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. | 登録日 | 2020-11-23 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
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7B7U
| Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Fianu, I, Dienemann, C, Aibara, S, Schilbach, S, Cramer, P. | 登録日 | 2020-12-11 | 公開日 | 2021-05-19 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Commun Biol, 4, 2021
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1YKE
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1YKH
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4A3G
| RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2012-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A3F
| RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A93
| RNA Polymerase II elongation complex containing a CPD Lesion | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ... | 著者 | Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M. | 登録日 | 2011-11-23 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage. Mol.Cell, 46, 2012
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4A3J
| RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP | 分子名称: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
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1ZP2
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4A3I
| RNA Polymerase II binary complex with DNA | 分子名称: | 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2012-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A3E
| RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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1Y14
| Crystal structure of yeast subcomplex of Rpb4 and Rpb7 | 分子名称: | DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II 32 kDa polypeptide | 著者 | Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. | 登録日 | 2004-11-17 | 公開日 | 2004-12-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7 J.Biol.Chem., 280, 2005
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4A3M
| RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A3B
| RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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1Y1V
| Refined RNA Polymerase II-TFIIS complex | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | 著者 | Kettenberger, H, Armache, K.-J, Cramer, P. | 登録日 | 2004-11-19 | 公開日 | 2004-12-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
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4A3L
| RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A3K
| RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
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4A3C
| RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-11-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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4A3D
| RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | 登録日 | 2011-09-30 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
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2C5Z
| Structure and CTD binding of the Set2 SRI domain | 分子名称: | SET DOMAIN PROTEIN 2 | 著者 | Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P. | 登録日 | 2005-11-03 | 公開日 | 2005-11-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription. J. Biol. Chem., 281, 2006
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1RNI
| Bifunctional DNA primase/polymerase domain of ORF904 from the archaeal plasmid pRN1 | 分子名称: | ORF904, ZINC ION | 著者 | Lipps, G, Weinzierl, A.O, von Scheven, G, Buchen, C, Cramer, P. | 登録日 | 2003-12-01 | 公開日 | 2004-01-27 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a bifunctional DNA primase-polymerase Nat.Struct.Mol.Biol., 11, 2004
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