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PDB: 24 件
3B39
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BU of 3b39 by Molmil
Structure of the DnaG primase catalytic domain bound to ssDNA
分子名称: DNA (5'-D(*DCP*DAP*DAP*DAP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DGP*DGP*DAP*DC)-3'), DNA primase
著者Corn, J.E, Pelton, J.G, Berger, J.M.
登録日2007-10-19
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Identification of a DNA primase template tracking site redefines the geometry of primer synthesis.
Nat.Struct.Mol.Biol., 15, 2008
2AU3
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BU of 2au3 by Molmil
Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)
分子名称: DNA primase, ZINC ION
著者Corn, J.E, Pease, P.J, Hura, G.L, Berger, J.M.
登録日2005-08-26
公開日2005-11-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crosstalk between primase subunits can act to regulate primer synthesis in trans.
Mol.Cell, 20, 2005
8AFI
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BU of 8afi by Molmil
GABARAP in complex with LIR motif of HsATG3
分子名称: ACETATE ION, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ...
著者Farnung, J, Benoit, R.M, Corn, J.E, Bode, J.W.
登録日2022-07-18
公開日2023-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.
Acs Cent.Sci., 9, 2023
3Q9N
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BU of 3q9n by Molmil
In silico and in vitro co-evolution of a high affinity complementary protein-protein interface
分子名称: CARBAMOYL SARCOSINE, COENZYME A, CoA binding protein, ...
著者Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC)
登録日2011-01-09
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A de novo protein binding pair by computational design and directed evolution.
Mol.Cell, 42, 2011
3Q9U
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BU of 3q9u by Molmil
In silico and in vitro co-evolution of a high affinity complementary protein-protein interface
分子名称: COENZYME A, CoA binding protein, consensus ankyrin repeat
著者Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC)
登録日2011-01-10
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A de novo protein binding pair by computational design and directed evolution.
Mol.Cell, 42, 2011
3H08
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BU of 3h08 by Molmil
Crystal structure of the Ribonuclease H1 from Chlorobium tepidum
分子名称: MAGNESIUM ION, Rnh (Ribonuclease H)
著者Ratcliff, K, Corn, J, Marqusee, S.
登録日2009-04-08
公開日2009-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic chlorobium tepidum: comparison with thermophilic and mesophilic homologues.
Biochemistry, 48, 2009
5TOG
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BU of 5tog by Molmil
Room temperature structure of ubiquitin variant u7ub25.2540
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
5TOF
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BU of 5tof by Molmil
Room temperature structure of ubiquitin variant u7ub25
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
4E2K
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BU of 4e2k by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain
分子名称: BENZAMIDINE, DNA primase
著者Rymer, R.U, Solorio, F.A, Clement, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-08
公開日2012-08-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDT
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BU of 4edt by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ppGpp and Manganese
分子名称: BENZAMIDINE, DNA primase, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDR
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BU of 4edr by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to UTP and Manganese
分子名称: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDV
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BU of 4edv by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese
分子名称: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EE1
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BU of 4ee1 by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese
分子名称: BENZAMIDINE, CYTIDINE-5'-TRIPHOSPHATE, DNA primase, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-28
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDK
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BU of 4edk by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese
分子名称: BENZAMIDINE, DNA primase, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDG
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BU of 4edg by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese
分子名称: ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
2M0X
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BU of 2m0x by Molmil
Solution structure of U14Ub1, an engineered ubiquitin variant with increased affinity for USP14
分子名称: engineered ubiquitin variant
著者Phillips, A.H, Fairbrother, W.J, Corn, J.E.
登録日2012-11-08
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LIM
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BU of 4lim by Molmil
Crystal structure of the catalytic subunit of yeast primase
分子名称: DNA primase small subunit, ZINC ION
著者Vaithiyalingam, S, Chazin, W.J, Berger, J.M, Corn, J, Stephenson, S.
登録日2013-07-02
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
2QBY
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BU of 2qby by Molmil
Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 6 homolog 1, Cell division control protein 6 homolog 3, ...
著者Cunningham Dueber, E.L, Corn, J.E, Bell, S.D, Berger, J.M.
登録日2007-06-18
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex.
Science, 317, 2007
7ZKC
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BU of 7zkc by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein
著者Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
登録日2022-04-12
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
7ZHB
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BU of 7zhb by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2)
分子名称: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
登録日2022-04-06
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published
7ZLE
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BU of 7zle by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
登録日2022-04-14
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
To Be Published
6FSN
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BU of 6fsn by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 1)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Roversi, P, Le Cornu, J.D, Hill, J, Alonzi, D.S, Zitzmann, N.
登録日2018-02-19
公開日2019-03-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.
Front Mol Biosci, 2022
7BCV
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BU of 7bcv by Molmil
Brevibacterium linens encapsulin structure
分子名称: Linocin-M18
著者Allende-Ballestero, C, Luque, D, Klem, R, Cornelissen, J.J.L.M, Caston, J.R.
登録日2020-12-21
公開日2022-10-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献Three-dimensional cryoEM structure of Brevibacterium linens encapsulin
To Be Published
7ZXW
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BU of 7zxw by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor
分子名称: 5-(morpholin-4-ylmethyl)quinolin-8-ol, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Le Cornu, J.D, Ibba, R, Roversi, P, Zitzmann, N.
登録日2022-05-23
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.
Front Mol Biosci, 9, 2022

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