5PEP
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![BU of 5pep by Molmil](/molmil-images/mine/5pep) | X-RAY ANALYSES OF ASPARTIC PROTEASES. II. THREE-DIMENSIONAL STRUCTURE OF THE HEXAGONAL CRYSTAL FORM OF PORCINE PEPSIN AT 2.3 ANGSTROMS RESOLUTION | Descriptor: | PEPSIN | Authors: | Cooper, J.B, Khan, G, Taylor, G, Tickle, I.J, Blundell, T.L. | Deposit date: | 1990-05-30 | Release date: | 1990-07-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution. J.Mol.Biol., 214, 1990
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5ER1
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2ER6
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![BU of 2er6 by Molmil](/molmil-images/mine/2er6) | The structure of a synthetic pepsin inhibitor complexed with endothiapepsin. | Descriptor: | ENDOTHIAPEPSIN, H-256 peptide | Authors: | Cooper, J.B, Foundling, S.I, Szelke, M, Blundell, T.L. | Deposit date: | 1990-10-13 | Release date: | 1991-01-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of a synthetic pepsin inhibitor complexed with endothiapepsin Eur.J.Biochem., 169, 1987
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1IDS
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![BU of 1ids by Molmil](/molmil-images/mine/1ids) | X-RAY STRUCTURE ANALYSIS OF THE IRON-DEPENDENT SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.0 ANGSTROMS RESOLUTIONS REVEALS NOVEL DIMER-DIMER INTERACTIONS | Descriptor: | FE (III) ION, IRON SUPEROXIDE DISMUTASE | Authors: | Cooper, J.B, Mcintyre, K, Wood, S.P, Zhang, Y, Young, D. | Deposit date: | 1994-09-29 | Release date: | 1994-12-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure analysis of the iron-dependent superoxide dismutase from Mycobacterium tuberculosis at 2.0 Angstroms resolution reveals novel dimer-dimer interactions. J.Mol.Biol., 246, 1995
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2ER9
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![BU of 2er9 by Molmil](/molmil-images/mine/2er9) | X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES. | Descriptor: | ENDOTHIAPEPSIN, L363,564 | Authors: | Cooper, J.B, Foundling, S.I, Boger, J, Blundell, T.L. | Deposit date: | 1990-10-20 | Release date: | 1991-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray studies of aspartic proteinase-statine inhibitor complexes. Biochemistry, 28, 1989
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2ER0
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![BU of 2er0 by Molmil](/molmil-images/mine/2er0) | X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES | Descriptor: | ENDOTHIAPEPSIN, L364,099 | Authors: | Cooper, J.B, Foundling, S.I, Boger, J, Blundell, T.L. | Deposit date: | 1990-10-20 | Release date: | 1991-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray studies of aspartic proteinase-statine inhibitor complexes. Biochemistry, 28, 1989
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4P9G
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![BU of 4p9g by Molmil](/molmil-images/mine/4p9g) | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. | Descriptor: | 2,4'-dihydroxyacetophenone dioxygenase, CARBONATE ION, FE (III) ION, ... | Authors: | Keegan, R, Lebedev, A, Erskine, P, Guo, J, Wood, S.P, Hopper, D.J, Cooper, J.B. | Deposit date: | 2014-04-03 | Release date: | 2014-09-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP Acta Crystallogr.,Sect.D, 70, 2014
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4PVM
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![BU of 4pvm by Molmil](/molmil-images/mine/4pvm) | Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue) | Descriptor: | Transthyretin | Authors: | Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T. | Deposit date: | 2014-03-18 | Release date: | 2014-11-12 | Last modified: | 2024-03-20 | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | Cite: | Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1, 2014
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1EPL
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![BU of 1epl by Molmil](/molmil-images/mine/1epl) | A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA | Descriptor: | ENDOTHIAPEPSIN, PS1, PRO-LEU-GLU-PSA-ARG-LEU | Authors: | Al-Karadaghi, S, Cooper, J.B, Strop, P, Blundell, T.L. | Deposit date: | 1994-07-27 | Release date: | 1994-12-20 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica. Protein Sci., 3, 1994
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1EED
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![BU of 1eed by Molmil](/molmil-images/mine/1eed) | X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors | Descriptor: | (2S)-2-[[(3S,4S)-5-cyclohexyl-4-[[(4S,5S)-5-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxidanyl-6-phenyl-hexanoyl]amino]-3-oxidanyl-pentanoyl]amino]-4-methyl-pentanoic acid, ENDOTHIAPEPSIN | Authors: | Blundell, T.L, Frazao, C, Cooper, J.B. | Deposit date: | 1992-06-15 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors. Biochemistry, 31, 1992
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1EPR
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![BU of 1epr by Molmil](/molmil-images/mine/1epr) | ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-135,040 | Descriptor: | ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide | Authors: | Badasso, M, Crawford, M, Cooper, J.B, Blundell, T.L. | Deposit date: | 1994-07-27 | Release date: | 1994-12-20 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica. Protein Sci., 3, 1994
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5A92
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![BU of 5a92 by Molmil](/molmil-images/mine/5a92) | 15K X-ray structure with Cefotaxime: Exploring the Mechanism of beta- Lactam Ring Protonation in the Class A beta-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography | Descriptor: | BETA-LACTAMASE CTX-M-97, CEFOTAXIME, C3' cleaved, ... | Authors: | Vandavasi, V.G, Weiss, K.L, Cooper, J.B, Erskine, P.T, Tomanicek, S.J, Ostermann, A, Schrader, T.E, Ginell, S.L, Coates, L. | Deposit date: | 2015-07-17 | Release date: | 2015-12-16 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Exploring the Mechanism of Beta-Lactam Ring Protonation in the Class a Beta-Lactamase Acylation Mechanism Using Neutron and X-Ray Crystallography. J.Med.Chem., 59, 2016
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5HNR
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![BU of 5hnr by Molmil](/molmil-images/mine/5hnr) | The X-ray structure of octameric human native 5-aminolaevulinic acid dehydratase. | Descriptor: | DELTA-AMINO VALERIC ACID, Delta-aminolevulinic acid dehydratase, SULFATE ION, ... | Authors: | Mills-Davies, N.L, Thompson, D, Shoolingin-Jordan, P.M, Erskine, P.T, Cooper, J.B. | Deposit date: | 2016-01-18 | Release date: | 2016-01-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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7OL1
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7P4R
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![BU of 7p4r by Molmil](/molmil-images/mine/7p4r) | Ultra High Resolution X-ray Structure of Orthorhombic Bovine Pancreatic Ribonuclease at 100K | Descriptor: | ETHANOL, Ribonuclease pancreatic, SULFATE ION | Authors: | Lisgarten, D.R, Palmer, R.A, Cooper, J.B, Naylor, C.E, Howlin, B.J, Lisgarten, J.N, Najmudin, S, Lobley, C.M.C. | Deposit date: | 2021-07-12 | Release date: | 2022-07-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K. BMC Chem, 17, 2023
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5OV6
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![BU of 5ov6 by Molmil](/molmil-images/mine/5ov6) | Bacillus megaterium porphobilinogen deaminase D82N mutant | Descriptor: | 3-[4-(2-hydroxy-2-oxoethyl)-2,5-dimethyl-1~{H}-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Guo, J, Erskine, P, Coker, A.R, Wood, S.P, Cooper, J.B. | Deposit date: | 2017-08-28 | Release date: | 2017-09-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5OT0
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![BU of 5ot0 by Molmil](/molmil-images/mine/5ot0) | The thermostable L-asparaginase from Thermococcus kodakarensis | Descriptor: | 1,2-ETHANEDIOL, L-asparaginase, PHOSPHATE ION, ... | Authors: | Guo, J, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Chohan, S.M, Akhtar, M. | Deposit date: | 2017-08-18 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structure and function of the thermostable L-asparaginase from Thermococcus kodakarensis. Acta Crystallogr D Struct Biol, 73, 2017
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5OV4
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![BU of 5ov4 by Molmil](/molmil-images/mine/5ov4) | Bacillus megaterium porphobilinogen deaminase D82A mutant | Descriptor: | Porphobilinogen deaminase | Authors: | Guo, J, Erskine, P, Coker, A.R, Wood, S.P, Cooper, J.B. | Deposit date: | 2017-08-28 | Release date: | 2017-10-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.692 Å) | Cite: | Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5OT1
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![BU of 5ot1 by Molmil](/molmil-images/mine/5ot1) | The type III pullulan hydrolase from Thermococcus kodakarensis | Descriptor: | CALCIUM ION, Pullulanase type II, GH13 family | Authors: | Guo, J, Coker, A.R, Wood, S.P, Cooper, J.B, Keegan, R, Ahmad, N, Muhammad, M.A, Rashid, N, Akhtar, M. | Deposit date: | 2017-08-18 | Release date: | 2018-04-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and function of the type III pullulan hydrolase from Thermococcus kodakarensis. Acta Crystallogr D Struct Biol, 74, 2018
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5OV5
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![BU of 5ov5 by Molmil](/molmil-images/mine/5ov5) | Bacillus megaterium porphobilinogen deaminase D82E mutant | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase | Authors: | Guo, J, Erskine, P, Coker, A.R, Wood, S.P, Cooper, J.B. | Deposit date: | 2017-08-28 | Release date: | 2017-09-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5L9A
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![BU of 5l9a by Molmil](/molmil-images/mine/5l9a) | L-threonine dehydrogenase from trypanosoma brucei. | Descriptor: | ACETATE ION, L-threonine 3-dehydrogenase | Authors: | Erskine, P.T, Cooper, J.B, Adjogatse, E, Kelly, J, Wood, S.P. | Deposit date: | 2016-06-09 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
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5LC1
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![BU of 5lc1 by Molmil](/molmil-images/mine/5lc1) | L-threonine dehydrogenase from Trypanosoma brucei with NAD and the inhibitor pyruvate bound. | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, L-threonine 3-dehydrogenase, ... | Authors: | Erskine, P.T, Adjogatse, E, Wood, S.P, Cooper, J.B. | Deposit date: | 2016-06-18 | Release date: | 2016-07-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
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1W31
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![BU of 1w31 by Molmil](/molmil-images/mine/1w31) | YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX | Descriptor: | 5-HYDROXYLAEVULINIC ACID, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Beaven, G.D.E, Gill, R, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2004-07-11 | Release date: | 2005-08-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid Acta Crystallogr.,Sect.D, 61, 2005
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5MDN
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![BU of 5mdn by Molmil](/molmil-images/mine/5mdn) | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis | Descriptor: | DNA polymerase, MAGNESIUM ION | Authors: | Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. | Deposit date: | 2016-11-12 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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5MHB
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![BU of 5mhb by Molmil](/molmil-images/mine/5mhb) | Product-Complex of E.coli 5-Amino Laevulinic Acid Dehydratase | Descriptor: | 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, Delta-aminolevulinic acid dehydratase, GLYCEROL, ... | Authors: | Norton, E, Erskine, P.T, Shoolingin-Jordan, P.M, Cooper, J.B. | Deposit date: | 2016-11-23 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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