5LC1
L-threonine dehydrogenase from Trypanosoma brucei with NAD and the inhibitor pyruvate bound.
Summary for 5LC1
Entry DOI | 10.2210/pdb5lc1/pdb |
Descriptor | L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ... (7 entities in total) |
Functional Keywords | dehydrogenase, holo-enzyme, rossman fold, oxidoreductase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 6 |
Total formula weight | 220064.09 |
Authors | Erskine, P.T.,Adjogatse, E.,Wood, S.P.,Cooper, J.B. (deposition date: 2016-06-18, release date: 2016-07-27, Last modification date: 2024-01-10) |
Primary citation | Adjogatse, E.,Erskine, P.,Wells, S.A.,Kelly, J.M.,Wilden, J.D.,Chan, A.W.E.,Selwood, D.,Coker, A.,Wood, S.,Cooper, J.B. Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74:861-876, 2018 Cited by PubMed: 30198897DOI: 10.1107/S2059798318009208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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